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Table of Contents - WOC 2012

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PO-RET-79<br />

Valsalva Retinopathy during labor<br />

Monica Orozco-Carroll (1) , Ricardo Agurto-Rivera (2)<br />

1. Ocuclinika<br />

2. Clinica Alemana de Santiago<br />

Objective: To present a valsalva retinopathy case during labor in a 29 years old<br />

female.<br />

Methods: Case Report<br />

Results: A 29-year-old woman during labor presented with a history <strong>of</strong><br />

decreased vision in her right eye. Examination <strong>of</strong> the affected eye showed<br />

best corrected visual acuity <strong>of</strong> hand movement, and fundus examination<br />

revealed an extensive pre-retinal hemorrhage covering almost all the macula.<br />

We performed a successfull hialoidectomy with ND:YAG laser and the vitreous<br />

hemorrhage created was selfsolved within one week. final best corrected<br />

visual acuity <strong>of</strong> the affectd eye was 20/25 and in the funfus examinations a<br />

epiretinal membrane was found.<br />

Conclusion: There are a few cases <strong>of</strong> valsalva retinopathy reported in the<br />

literature, none as extensive as this case, in all cases, the Nd:YAG laser<br />

treatment were susccessfull. As our patient, all <strong>of</strong> the patients developed<br />

epiretinal membrane<br />

PO-RET-80<br />

Morphological changes <strong>of</strong> the retina in occult macular dystrophy<br />

Sekiryu Tetsuju (1) , Sugano Yukinori (1) , Ichiro Maruko (1) , Iida Tomohiro (1)<br />

1. Fukushima medical university<br />

Purpose : To assess morphological changes <strong>of</strong> the retina in occult macular<br />

dystrophy (OMD) by using spectral domain optical coherence tomography<br />

(SD-OCT).<br />

Methods: Retrospective observational study. We evaluated the findings <strong>of</strong> SD-<br />

OCT in five patients who had a normal ocular examination and low voltage<br />

in multifocal electroretinograms. Central foveal thickness (CFT) and outer<br />

nuclear thickness (ONT) in OMD was measured and compared to that in<br />

normal volunteers.<br />

Results: The mean CFT and ONT in the patients were 143.2 ?m ± 20.2 (SD)<br />

and 80.3?m ± 15.73 (SD) and significantly thinner than those in 35 normal<br />

volunteers. The intermediate line between layers <strong>of</strong> the retinal pigment<br />

epithelium disappeared in all eyes <strong>of</strong> the patients.<br />

Conclusion:?The photoreceptor cells including the outer segment are affected<br />

in the eyes with OMD. OCT findings are valuable to improve the accuracy <strong>of</strong><br />

diagnosis and elucidate the pathogenesis <strong>of</strong> OMD.<br />

PO-RET-81<br />

Influence <strong>of</strong> intravitreal injections <strong>of</strong> anti-VEGF agents and antibiotic<br />

eye drops to the stability <strong>of</strong> tear film and dry eye.<br />

Radecka Liga (1) , Laganovska Guna (1) , Kozlova Kristine (1)<br />

1. Riga Stradins University<br />

Purpose: To evaluate and analyse changes <strong>of</strong> tear film break-up time (BUT)<br />

after intravitreal injections <strong>of</strong> anti-VEGF (Bevacizumab) and prophylactic use<br />

<strong>of</strong> broad spectrum antibiotic eye drops (Lev<strong>of</strong>loxacinum).<br />

Methods: In the study group we included 30 eyes treated with anti-VEGF and<br />

in control group we included the fellow eyes. We examine BUT and compare<br />

results <strong>of</strong> both groups.<br />

Results: In the study we included 30 patients (13 - male, 17 - female) from age<br />

36 to 92 (average - 73 years). The number <strong>of</strong> intravitreal injections was from<br />

1 to 22 (median - 3). The mean tear film break-up time in the study group was<br />

8,23seconds (SD - 1,74), but in control group the mean BUT was 8,00 seconds<br />

(SD - 1,86).<br />

Conclusion: Our results show that use <strong>of</strong> intravitreal anti-VEGF agents and<br />

prophylactic use <strong>of</strong> broad spectrum antibiotics do not have essential impact on<br />

the tear film stability and dry eye.<br />

<strong>WOC</strong><strong>2012</strong> Abstract Book<br />

PO-RET-82<br />

Observational study on the role <strong>of</strong> presenting vision on visual<br />

outcome in Wet Age-related Macular Degeneration (AMD) in a onestop<br />

district general hospital in UK<br />

Ranganath Akshatha (1) , Gerges Sami (1)<br />

1. Ophthalmology Department, Barnsley District General Hospital<br />

Objectives: To determine importance <strong>of</strong> presenting vision in patients with wet<br />

AMD and to assess it›s effect on visual prognosis following treatment.<br />

Methods: Retrospective study <strong>of</strong> 167 patients (201 eyes) treated for wet-AMD<br />

between February 2009 to August 2010 in a secondary care retinal practice. All<br />

patients included in the study received at least 3 loading doses <strong>of</strong> Ranibizumab<br />

at 4 weeks interval after confirming diagnosis by clinical examination, Fundus<br />

Fluorescein Angiography & Optical Coherence Tomography. A trained nurse<br />

specialist recorded Best Corrected Visual Acuity (BCVA) using the Early<br />

Treatment <strong>of</strong> Diabetic Retinopathy (ETDRS) vision chart at first visit and then<br />

at subsequent visits.<br />

Results: 187 eyes met the inclusion criteria. In patients with presenting vision<br />

between 75-45 letters (0.3 - 0.8 Log MAR) 61% showed an improvement in<br />

vision and 17% worsened. Among those with < 45 letters (0.8 Log MAR), only<br />

28% improved and 51% deteriorated even after treatment irrespective <strong>of</strong> the<br />

type <strong>of</strong> lesion.<br />

Conclusions: Increase in BCVA after Ranibizumab treatment is well established.<br />

This study highlights that visual prognosis is much better in patients with<br />

presenting vision >45 letters. The beneficial effects <strong>of</strong> ranibizumab are more<br />

significant when treatment is started early and prompt referral pathways are<br />

crucial to avoid delay in assessment and treatment <strong>of</strong> wet AMD.<br />

PO-RET-83<br />

Outcome <strong>of</strong> Peripapillary LASER and Gas tamponade for<br />

maculopathy associated with Optic disc pit<br />

Fegde Sachin (1) , Haldipurkar Suhas (1) , Shetty Vijay (1) , Giridhar A (1)<br />

1. Laxmi Eye Institute<br />

Purpose : To evaluate the efficacy <strong>of</strong> peripapillary laser treatment and gas<br />

tamponade as a treatment modality for macular detachment associated with<br />

optic disc pit Design : Noncomparative, interventional case series involving 8<br />

consecutive patients presenting with unilateral macular detachment associated<br />

with an Optic disc pit Intervention : LASER photocoagulation to the area <strong>of</strong> pit<br />

and intravitreal injection <strong>of</strong> 0.3 cc C3F8 gas with face down positioning for 10<br />

days. OCT used to monitor the anatomic changes, with a follow-up <strong>of</strong> 3 months<br />

to 12 months (mean 6.5 months). Results : Complete retinal reattachement<br />

was observed 6 out <strong>of</strong> 8 eyes. The mean pretreatment BCVA was 0.88 logMAR<br />

units and mean posttreatment BCVA was 0.40 logMAR units. More than 3 lines<br />

<strong>of</strong> BCVA gain was observed in 4 out <strong>of</strong> 8 eyes. Secondary Glaucoma was<br />

observed in 1 eye and none <strong>of</strong> the eyes required retreatment.<br />

Conclusion : Results suggest that peripapillary laser and gas tamponade is<br />

successful in treatment <strong>of</strong> macular detachment, improving central vision in<br />

patients with Optic Disc Pit.<br />

621

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