Table of Contents - WOC 2012

WOC2012 Abstract Book
PO-STR-06
Genetic Diagnosis from Buccal Cells in Patients with
Ophthalmoplegia
Torii Kaoruko (1) , Negishi Takashi (1,2) , Hosono Katsuhiro (1) , Sawada Mayu (1) ,
Hikoya Akiko (1) , Sato Miho (1) , Hotta Yoshihiro (1)
1. Hamamatsu University School of Medicine
2. Juntendo University
Purpose: Chronic progressive external ophthalmoplegia (CPEO) is frequently
associated with a large deletion of the mitochondrial DNA (mtDNA). Recent
report shows that PCR of buccal cells is a less invasive method for the
diagnosis of CPEO. We performed genetic diagnosis of the mtDNA from buccal
cells in patients with opththalmoplegia.
Methods: Case 1 is a 26-year-old male with exotropia and ptosis. He had a
history of ptosis repair. Eye movement was limited in all directions except
abduction. Case 2 is a 71-year-old female with a history of strabismus surgery
for exotropia 3 times and a ptosis repair. She had adduction weakness. Case
3 is a 74-year-old male who had exotropia with weakness of adduction and
infraduction and ptosis. DNA was extracted from buccal cells and amplified
between nucleotide position 4621 and 16449 of the mtDNA by PCR
amplification after the informed consent. Several additional PCR amplifications
were performed encompassing deletion suspected area and estimated the
deletion size.
Results: We detected about 5 kbp deletion only in case 1. Both normal and
abnormal bands were detected in PCR product suggesting the heteroplasmy.
Conclusion: Genetic diagnosis from buccal cells can be used for the diagnosis
of CPEO.
PO-STR-07
To evaluate the surgical outcome of suspension recession technique
of inferior oblique in the management of V pattern associated with
Inferior oblique overaction ( IOOA)
(1) (2) (3) (4)
Kamlesh
1. Maulana Azad Medical College
Objective: To evaluate the surgical outcome of suspension recession technique
of inferior oblique in the management of V pattern associated with Inferior
oblique overaction ( IOOA) Material & Methods : Inferior oblique suspension
recession technique was tried in 30 patients in children above the age of five
yearsin Vpattern associated with IOOA. Results ; Vpattern was corrected in
90% patients
Conclusion : inferior oblique suspension recession techniques is an easy
,quick and effective landmark free technique for cases of V pattern with IOOA.
This procedure has an an extra advantage of per operative and postoperative
customization of the inferior oblique muscle.
PO-STR-08
TELEVISION GAMES AS NEAR VISUAL ACTIVITIES IN THE
TREATMENT OF AMBLYOPIA IN CHILDREN AGED 4-7 YRS
dadeya subhash (1) , Dangda Sonal (2) (3) (4)
, Sinha Ekta
1. Maulana Azad Medical College
2. Guru Nanak Eye Center
3. Guru Nanak Eye Center
aim: To study the role of television games in amblyopia treatment.
Methods: Forty children aged 4 to 7 years, with amblyopia were divided into
two groups of twenty each and were given full time occlusion of better eye
according to thumb age rule. Patients in group B were given additional near
visual activities with the aid of television games at a distance of 1 mt. for half
an hour every week for twelve weeks. Study visits were scheduled at 3, 6,
9 and 12 weeks.RESULTS: Statistically significant improvement in visual
acuity (distance and near) was noted in both the groups but the difference in
improvement, between the two groups, in terms of mean visual acuity (0.38 vs
0.31for dist and 8.9 vs 6.3 for near) and lines of improvement (2.5 vs 1.6 dist,
p value 0.005) ( 2.85 vs 1.6 near, p value 0.000) was greater in patching with
near exercises (television games) group as compared to patching alone group
at all the follow up visits.CONCLUSION: Near visual activities in the form of
television games are beneficial in amblyopia treatment.
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PO-STR-09
Psychosocial and functional value of strabismus surgery in adults.
Perez-Flores Ines (1) , Lorenzo-Carrero Jose (1) , García Marta (2) , Cores Javier
(3)
1. Department of Ophthalmology. Hospital POVISA
2. Department of Ophthalmology. Hospital Xeral-Cies
3. Department of Ophthalmology. Hospital Provincial
PURPOSE To evaluate the impact of strabismus and strabismus surgery in
adults from the patient perspective. METHOD In a prospective study we asked
24 adults (?16 years old), diagnosed of esotropia (ET) or exotropia (XT) to
complete a psychosocial and functional questionnaire preoperatively and
postoperatively (1month). RESULTS Preoperatively, 14 (58%) patients claimed
that they felt rejected, and 12 (52.1%) affirmed that they had had working
troubles. After surgery 24 (100%) patients felt better with their appearance;
21(87.5%) felt more confident in personal relationship and 18 (78.2%) well
considered and more comfortable at work. Preoperatively no patient showed
torticollis or diplopia, although 18 (75%) affirmed that they turned head/face to
see better and 16(66,7%) needed wink his eye. After surgery this complaint
was present in only 12 (50%) and 11 (45,9%) patients, respectively. Six (25%)
patients felt that his visual field had increased and 4(16.7%) believed that they
could calculate distance and depth better than before surgery. CONCLUSION
Strabismus surgery increases self-confidence, improves personal and working
relationship in adults with strabismus. From the functional point of view some
patients increased their fusional ability and their visual field. Ophthalmologist
must be learned about the potential benefits of strabismus surgery in adults.
PO-STR-10
Our experience with monocular elevation deficit syndrome patients
Shah Shreya (1) , Shah Mehul (1) , Appalware Adway (1) , Kalyani Janak (1)
1. Drashti Netralaya
PURPOSE : To share experience regarding management & results of patients
with Monocular Elevation Deficit Syndrome (MEDS). METHOD :14 patients
having MEDS were examined thoroughly& surgical correction done. strabismus
, ptosis , ocular motility & Bell›s phenomena. Forced Duction Test were taken
into account.Ptosis correction done by frontalis sling or LPS Resection &
amount of Bell›s phenomena taken into account to prevent exposure keratitis.
RESULTS : 8 ptients have good Bell›s phenomena & ortho position in primary
gaze, 2 patients have poor Bell›s phenomena & hypotropia 10 ^ in primary
gaze, 3 patients awaited for follow up, 1 lost to follow up,
Conclusion : MEDS is a treatable entity & can give reasonably good outcomes
when tackeled systematically using the above criteria.
PO-STR-11
Extraocular muscle surgery for conjugate deviation
Kimura Akiko (1) , Mimura Osamu (1) , Masuda Akiko (1) , Nakamura Yumiko (1) ,
Kimura Naoki (1)
1. Hyogo College of Medicine
Objective) In conjugate deviation, both eyes deviate in one direction and gaze
palsy toward the opposite side occurs, which causes the abnormal head
posture of widely turning the face. In this study, we investigated the effect
of the extraocular muscle sugery for conjugate deviation in 11 patients.
Methods) The subjects were 11 patients (aged 21-74 years) who underwent
the extraocular muscle surgery for conjugate deviation at Hyogo College of
Medicine Hospital between November 2005 and January 2011. The extraocular
muscle sugery was basically performed based on the Anderson procedure:
Recession of the horizontal contralateral synergists on the side of conjugate
deviation and shortening of the contralateral synergists on the contralateral
side of conjugate deviation were performed simultaneously or stepwisely. The
surgical procedure, postoperative free head posture, and surgical effect were
investigated. Results) The mean angles of pre- and postoperative abnormal
head postures were 23 and 3 (0-10) degrees, respectively, showing that the
abnormal head posture was mostly resolved in all patients. No abnormal head
posture was improved by the Anderson procedure alone. Conclusion) Surgery
of the extraocular muscles for conjugate deviation was effective and resolved
an abnormal head posture.