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Table of Contents - WOC 2012

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<strong>WOC</strong><strong>2012</strong> Abstract Book<br />

PO-RET-55<br />

Prepapillary vascular loops<br />

Radhakrishnan Meenambigai (1) , Fonseka Charith (1) , Dissanayaka Mangala (1)<br />

1. National Eye Hospital<br />

A case report <strong>of</strong> a 26 years old woman with bilateral multiple prepapillary<br />

vascular loops and vitreous haemorrhage in the left eye. Colour fundus<br />

photograph and fluoresceine angiography <strong>of</strong> the condition are presented.<br />

These loops are normal retinal blood vessels that have grown into the<br />

Bergmeister papillae before returning to the optic disc. The loops are 0.5mm<br />

to 5mm in length. They are congenital in origin. Spontaneous resorption <strong>of</strong><br />

vitreous haemorrhage is the rule and the prognosis is excellent.<br />

PO-RET-56<br />

Blue Peak Aut<strong>of</strong>luorescence - An Insight into the Metabolic Activity<br />

in Retinal Disease<br />

Gopalakrishnan Mahesh (1) , Vyas Jyotiprakash (1) , Giridhar Anantharaman (1)<br />

1. Giridhar eye institute.<br />

PURPOSE: Togive an overview <strong>of</strong> blue peak fundus aut<strong>of</strong>luorescence (FAF)<br />

imaging and its applications in evaluation <strong>of</strong> retinal diseases MATERIALS AND<br />

Methods:FAF imaging was performed in normal eyes in all age groups (30-<br />

70yrs) and also in various retinal diseases.<br />

Results:Blue peak aut<strong>of</strong>luorescence pattern is a combination <strong>of</strong> blue laser and<br />

confocal scanning, which helps in mapping <strong>of</strong> lip<strong>of</strong>ucsin, a naturally occurring<br />

metabolic indicator found in retinal pigment epithelial(RPE) cells. As various<br />

hereditary and acquired retinal disorders manifest with altered metabolic<br />

activity <strong>of</strong> the RPE-photoreceptor complex, FAF helps in identifying the<br />

changes in FAF pattern in these disorders.<br />

Conclusion: Blue peak aut<strong>of</strong>luorescence serves as a newer non-invasive<br />

diagnostic modality which helps to diagnose and provide an insight into the<br />

visual prognosis <strong>of</strong> macular disorders.<br />

PO-RET-57<br />

Bilateral neurosensory detachment in macular area simulating<br />

central serous chorioretinopathy in a patient with Chronic Myeloid<br />

Leukemia with ongoing treatment - a case report.<br />

Addoor Krishna rao (1) , Kamath Ajay (1) , K Ravi Chandra (1) , G Lavanya Rao (1)<br />

1. MANIPAL UNIVERSITY<br />

Case report : A 30 year old male patient <strong>of</strong> Chronic Myeloid Leukemia, on<br />

Imatinib Mesylate since 5 months presented to us with bilateral diminution <strong>of</strong><br />

vision <strong>of</strong> 2 weeks duration.His best corrected visual acuity was [RE] 6/18 and<br />

[LE] 6/24.On examination, anterior segment was normal in [BE] and fundus<br />

showed bilateral serous elevation <strong>of</strong> macula with subretinal precipitates<br />

and retinal folds.FFA showed small multiple hyperfluorescent spots in the<br />

perifoveal area increasing in size and intensity with subretinal pooling <strong>of</strong> dye<br />

in late phases, simulating central serous chorioretinopathy.OCT confirmed<br />

the findings. Discussion : Central serous chorioretinopathy like picture in this<br />

patient may be due to fluid retention,an adverse effect <strong>of</strong> Imatinib Mesylate.<br />

There are very few cases <strong>of</strong> subretinal fluid retention reported s<strong>of</strong>ar.Causes<br />

are speculative,may be due to downregulation <strong>of</strong> kinases like Platelet Derived<br />

Growth Factor Receptor, which are expressed in retina.<br />

616<br />

PO-RET-58<br />

A case <strong>of</strong> cone dystrophy with initial diagnosis <strong>of</strong> congenital<br />

nystagmus<br />

Yokochi Midori (1) , Li Danjie (1) , Ikeda Fumiko (1) , Kishi Shoji (1)<br />

1. Department <strong>of</strong> Ophthalmology, Gunma University School <strong>of</strong> Medicine<br />

Objective: To report a case <strong>of</strong> congenital nystagmus whose cone dystrophy<br />

was revealed at age 4 years by electroretinogram (ERG) and spectral domain<br />

optical coherence tomography (OCT). Case report: A 4-months-old male<br />

baby referred to us with congenital nystagmus. The baby was born normal<br />

delivery and had no familiar history. The nystagmus was involunlary, repetitive,<br />

to-and-fro oscillation. His refractive state was 3.5~4.0D hyperopia in both<br />

eyes. Anterior ocular segment and ocular fundus were normal in both eyes by<br />

ophthalmologic examination. He was treated with glasses under diagnosis <strong>of</strong><br />

ametropic amblyopia at age 2 and half years. His visual acuity was 0.09 in both<br />

eyes at age 4 and half years. ERG revealed that rod and maximal responses<br />

was normal or slightly decreased, but the cone and 30Hz flicker responses<br />

were flat. At age 5 years, OCT revealed that reflection <strong>of</strong> photoreceptor inner<br />

and outer segment junction was unclear in the macular area. At age 6 years,<br />

the visual acuity remained 0.07 in right, 0.09 in left eye. Cone and flicker<br />

responses were non recordable in both eyes.<br />

Conclusion: Cone dystrophy was diagnosed by ERG and OCT in a baby with<br />

congenital nystagmus whose fundus appeared normal.<br />

PO-RET-59<br />

Central serous Retinopathy-A rare presentation in Pregnancy<br />

Pai Shobha (1) , Kamath Gurudutt, Karat Shubashree, Pai Ajay<br />

1. Kasturba Medical College,Manipal University<br />

Introduction: Central serous retinopathy although not typical has been reported<br />

to occur during pregnancy and is known to be self limiting. Case report: A 27<br />

year old female presented with blurred vision and distortion <strong>of</strong> images in her<br />

left eye since one week in the seventh month <strong>of</strong> her second pregnancy. On<br />

examination the visual acuity <strong>of</strong> right eye was 6/6 and in the involved left eye<br />

it was 6/12. Amsler grid <strong>of</strong> right eye was normal, left eye showed distortion<br />

<strong>of</strong> the central area. Dilated fundus examination revealed a normal right eye<br />

and left eye showed a round, serous elevation <strong>of</strong> the retina measuring two<br />

disc diameters in size involving foveal center with subretinal exudates. OCT<br />

showed a serous retinal detachment at macula. A week later patient reported<br />

an improvement in vision but distortion persisted. A month later visual acuity<br />

improved to 6/9. Fundus examination and OCT showed resolving serous<br />

detachment with persisting subretinal exudates.<br />

Conclusion: CSR in pregnancy is rare, 61% <strong>of</strong> which occurs in the third<br />

trimester. The condition resolves spontaneously in the first few months postpartum.<br />

This case report reaffirms the self limiting nature <strong>of</strong> the disease even<br />

in pregnancy.<br />

PO-RET-60<br />

A case <strong>of</strong> toxic optic neuropathy with methanol<br />

Magori Mikiya (1) , Shimoda Yukitoshi (1) , Hashimoto Hideaki (1) , Sano Morihiko<br />

(1) (1)<br />

, Kishi Shoji<br />

1. Department <strong>of</strong> Ophthalmology, Gunma University School <strong>of</strong> Medicine<br />

Introduction: We report a case <strong>of</strong> toxic optic neuropathy caused by a window<br />

washer fluid containing methanol. Case: A 47 - year-old male had alcoholism.<br />

He drank alcohol for a week and took a window washer fluid on the last two<br />

days. He became ill due to acidosis and his visual acuity fell to light sense in<br />

both eyes. Fundus showed swelling <strong>of</strong> the optic disc but the macula appeared<br />

normal. MRI revealed a high signal in bilateral basal ganglia in his brain, which<br />

suggested methanol toxicity. High concentration <strong>of</strong> methanol was detected in<br />

his urine. Emergent dialysis was performed. At day 8, best corrected visual<br />

acuity (BCVA) improved to 1.2 in both eyes. At day 40, spectral domain optical<br />

coherence tomography showed thinning <strong>of</strong> inner retina and retinal nerve fiber<br />

layer defect in the macula. Optic disc swelling disappeared and optic disc<br />

cupping was enlarged. At 7 months, right BCVA was 0.2 and left was 0.02.<br />

Both optic discs were atrophic. Visual field was constricted in the right eye and<br />

a central scotoma remained in the left eye.<br />

Conclusion: Methanol optic neuropathy involved retinal nerve fiber layer defect<br />

and thinning <strong>of</strong> inner retina.

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