Table of Contents - WOC 2012

FP-RET-TH 22 (5)
Advantages of Subthreshold Micropulse 577 nm Yellow Laser
Combined with Intravitreal Ranibizumab in Comparison with
Ranibizumab as Monotherapy in Cystoid Macular Edema Secondary
to Branch Retinal Vein Occlusion
Saksonov Stanislav (1) , Suk Sviatoslav (1) , Rykov Sergiy (1) , Kuznetsova
Tatyana (1) , Shevchenko Vadym (1)
1. Eye Microsurgery Center
Purpose: To compare the efficacy of subthreshold micropulse (s.micr.p.) 577
laser photocoagulation and no ophthalmoscopically visible endpoint combined
with intravitreal (IVT) ranibizumab to IVT ranibizumab as monotherapy in the
treatment of cystoid macular edema (CME) secondary to branch retinal vein
occlusion(BRVO).
Methods: 42 patients(pat.)(42 eyes) with CME due to BRVO. In the control
group (22pat.-22 eyes)laser treatment was performed as monotherapy with
3 consecutive IVT.In the main group (20pat.-20 eyes) modified s.micr.p.laser
treatment with 577 laser was performed in combination with 1 IVT ranibizumab.
Visual acuity(VA),contrast sensitivity, biomicroophthalmoscopy, fundus
photography, fluorescein angiography(FA) and central macular thickness(CMT)
at optical coherence tomography(OCT)were evaluated at baseline,month
1,3,6,12.
Results: 9 months from treatment, the main group: VA increased in 17 eyes
(85%), stable in 2 eyes(10%),worsened 1eye(5%) with respect to baseline. The
control group: VA increased in 16 eyes (73%), stable in 4 eyes(18%),worsened
in 2eyes(9%). Mean CMT according to was 237 µm in the main group, 259
µm in the control group(p=0,05). Regression of retinal thickness was achieved
in 19 eyes (95%) in the main group and in 20eyes (90%)of the control group
(p