Table of Contents - WOC 2012

WOC2012 Abstract Book
PO-COR-30
Ocular Manifestations in a Patient with Ectrodactyly-Ectodermal
Dysplasia-Cleft Syndrome.
Garza-Leon Manuel (1,2) , Morales-Ochoa Hortencia (3)
1. Destellos de Luz non profit Fundation
2. Instituto para Preservacion de la vision
3. Instituto Mexicano del Seguro Social
Purpose: To report the clinical characteristics in a case of ectodermal dysplasia,
ectrodactyly and clefting syndrome (EEC).
Method: Case report.
Results: We present a case of female patients, who complains of decreased
vision and photophobia of 6 years, ophthalmic evaluation shows absence of
the meibomian glands and madarosis. Corneal manifestations were bilateral
central vascularized corneal scars. Skeletal anomalies were ectrodactyly
and lobster-claw deformity of both hands; facial anomalies were scare in the
superior lip secondary to the surgical repair of the cleft lip and palate. With
the systemic findings a diagnosis of ectodermal dysplasia, ectrodactyly and
clefting syndrome was made.
Conclusion: It is important to make a full ophthalmic and systemic evaluation in
all patients with corneal scars to rule out associated systemic diseases.
Ectodermal dysplasia, ectrodactyly and clefting syndrome can produce corneal
neovascularization and scar secondary to chronic alterations of the surface
and adnexae produced by the obstructed tear ducts; secondary tear film lipid
layer deficiency; and primary corneal epithelial defects, usually in the early
adulthood.
PO-COR-31
Use of Systemic Interferon Alpha-2a for the Treatment of Severe Dry
Eye Due to Hepatitis C Infection
Gracia García Alicia (1) , Calvo Andrés Ramon (1) , Navarro Palop Catalina (1) ,
Domenech Aracil Nuria (1) , Cervera Taulet Enrique (1)
1. Hospital General Universitario Valencia
Purpose: To report a case presentation that the clinical management of the dry
eye improved with systemic interferon.
Methods: To report a clinical case of a 64-year-old woman with severe dry eye
syndrome associated with chronic hepatitis C. Subjective symptoms of ocular
dryness, signs were scored (corneal fluorescein staining, tear film break-up
time, standard Schirmer test) and best-corrected visual acuity (BCVA) was
measured. Topical treatment was started with high density artificial tears,
dexpantenol ophthalmic ointment and cloranfenicol. Six weeks after the ocular
symptoms started, the patient received subcutaneous interferon ?-2a therapy
(180 mcg/week) with ribavirin 1000 mg/day orally for the initial treatment of
patients with chronic hepatitis C.
Results: The patient received interferon therapy during six months. She was
examined one month before and one, three and six months after the beginning
of the treatment. Three months later, the ulcer layer epithelized totally and all
dry eye parameters improved. The BCVA increased from counting fingers to
20/100.
Conclusions: Systemic interferon alpha-2a treatment might be an effective
therapeutic strategy in patients with severe dry eye syndrome due to hepatitis
C infection. Its use could improve autoimmune and inflammatory factors that
can predispose to conventional dry eye treatment failure.
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PO-COR-32
New Surgical Technique for Trimming Glaucoma Tubes in
Complicated Cornea and Aphakic Eyes- The NECKLACE Technique
Wang Jenn Chyuan (1)
1. Singapore National Eye Centre
Objective: To describe a new surgical technique which allows safe and efficient
way to shorten and remove the intra-ocular portion of the glaucoma drainage
tube in conditions of media opacity and previous complicated cataract surgery.
Methods: Demonstration of surgical technique in a single case of pseudophakic
eye with bullous keratopathy undergoing Descemet Stripping Endothelial
Keratoplasty Surgery. A Ethicon CTC-6 needle is used to pierce through the
distal end of the of silicone tube. The needle exists through the main wound.
The other end of the suture is retrieved via the main wound using a Kelman
forceps. Both ends of the suture provide countertraction when the tube is cut,
using an intra-ocular scissors, to the desired length.
Results: The cut end is withdrawn safely out of the eye together with the suture.
Conclusion: This simple technique provides a simple, safe and efficient way to
shorten the glaucoma drainage tube conditions of media opacity and previous
complicated cataract surgery.
PO-COR-33
Intacs SK IntraCorneal Ring Segment in the Management of
Keratoconus
Khan Mohammad Irfan (1) , Injarie Anas (1) , Muhtaseb Mohammed (1)
1. Singleton Hospital Abertawe Bro Morgannwg University NHS Trust
Purpose: To report the safety and efficacy of Intacs SK in the management of
keratoconus.
Methods: Retrospective non-randomized study of patients who had Intacs SK
implanted manually for moderate to severe keratoconus and contact lens
intolerance or ineffectiveness. Patients were seen at 0.5, 1, 3, 6, 9 and 12
months post operatively. Outcome measures included uncorrected (UCVA)
and best corrected (BCVA) visual acuity, refraction, corneal topography and
slit lamp examination.
Results: 31 eyes of 29 patients were evaluated. The mean UCVA was
significantly better at 12 months postoperatively than preoperatively (0.88
LogMAR versus 1.4 LogMAR) (P=0.001), as was the mean BCVA (0.29
LogMAR versus 0.44 LogMAR) (P=0.04). The mean keratometry readings
were reduced from 52.07 D (range 45.9 to 63.1D) to 46.15D (range 39.2 to
52.9D) for K1 (P