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Table of Contents - WOC 2012

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<strong>WOC</strong><strong>2012</strong> Abstract Book<br />

IS-RET-MO 355 (2)<br />

Surgical Approach to Retinal and Choroidal Biopsy<br />

Elliot Dean (1)<br />

1. Massachusetts Eye & Ear Infirmary, Harvard Medical School<br />

Chorioretinal biopsy is a useful procedure in cases <strong>of</strong> retinal and/or choroidal<br />

infiltration <strong>of</strong> unknown etiology. With the assistance <strong>of</strong> a skilled pathologist,<br />

the procedure increases the likelihood <strong>of</strong> diagnosing or excluding certain<br />

conditions such as infection and lymphoma. With proper surgical technique,<br />

the complication rate is low. This presentation will utilize surgical videos to<br />

demonstrate the technique <strong>of</strong> chorioretinal biopsy in cases that present a<br />

diagnostic challenge.<br />

IS-RET-MO 355 (3)<br />

Processing <strong>of</strong> the Vitreous, Retina and Choroidal Biopsy<br />

Edward Deepak (1,2)<br />

1. Wilmer Eye Institute, Johns Hopkins University<br />

2. King Khaled Eye Specialist Hospital<br />

The diagnosis <strong>of</strong> vitreous, retinal and choroidal diseases that are inflammatory,<br />

infectious or neoplastic in nature, can be challenging. Tissue biopsies are<br />

<strong>of</strong>ten necessary and are valuable in the diagnosis <strong>of</strong> such conditions. This<br />

presentation will highlight the methods <strong>of</strong> obtaining biopsies from these tissues<br />

that are acceptable to the pathologists. The presentation will also include<br />

methods <strong>of</strong> collection, transportation and specific histologic and molecular<br />

tests each <strong>of</strong> which will be illustrated using clinical examples.<br />

IS-RET-MO 355 (4)<br />

Choroidal Biopsy in Diagnosis <strong>of</strong> Uveal Neoplasia<br />

Coupland Sarah (1)<br />

1. University <strong>of</strong> Liverpool<br />

Aims: To report our experience in choroidal intraocular biopsy for diagnosis <strong>of</strong><br />

uveal neoplasia. Methods: Intraocular biopsy may be required to establish the<br />

diagnosis <strong>of</strong> clinically uncertain choroidal tumours, in particular to differentiate<br />

between primary choroidal and secondary choroidal malignancies. These<br />

biopsies vary in size and complexity, ranging from fine needle aspiration,<br />

25-guage biopsies, endoresections to local resection specimens.<br />

Results: ‹Tips and tricks› for the fixation and processing <strong>of</strong> intraocular tissue<br />

biopsies are provided. Most solid tissue samples can be placed in buffered<br />

formalin, with the exception <strong>of</strong> those requiring RNA-based molecular<br />

techniques, here fresh tissue being preferable. The importance <strong>of</strong> incorporating<br />

data from all investigations and summarizing them as an integrated report is<br />

emphasized. The pitfalls <strong>of</strong> using any single test (e.g. a molecular genetic test)<br />

as a ‹stand alone› investigation emphasised.<br />

Conclusion: Communication with relevant clinical information between surgeon<br />

and pathologist is essential at each stage: for sample delivery, for exclusion<br />

<strong>of</strong> differential diagnoses and for rapid result transmission. The current<br />

immunohistochemical and molecular genetic techniques for lymphoma and for<br />

uveal melanoma prognostication are summarized, and how their data can be<br />

used for instigation <strong>of</strong> individualized management plans for patients discussed<br />

IS-RET-MO 355 (5)<br />

Retinal Biopsy Pathology in Diagnosis <strong>of</strong> Retina Neoplasia and<br />

Infections<br />

Vitor Vasconcelos Santos Daniel (1)<br />

1. Universidade Federal de Minas Gerais<br />

Retinal biopsy is an important alternative for the definite diagnosis and<br />

adequate management <strong>of</strong> atypical cases <strong>of</strong> intraocular inflammation, particularly<br />

those associated with neoplasia or infection. The role <strong>of</strong> retinal biopsy in such<br />

setting will be discussed, emphasizing the main indications, proper processing<br />

<strong>of</strong> the specimens and interpretation <strong>of</strong> the microscopic findings. Illustrative<br />

cases will clinicopathological correlation will also be presented and discussed.<br />

338<br />

Asian Eyelid Surgery: Pearls and Pitfalls<br />

Mon 20 Feb 8:30 - 10:00 Hall 9<br />

IS-OCP-MO 356 (1)<br />

Finesse in Asian Upper Blepharoplasty<br />

Chee Chew Yip (1)<br />

1. Khoo Teck Puat Hospital Singapore<br />

Asian upper blepharoplasty poses a different surgical challenge to the<br />

oculoplastic surgeon. It is crucial that the anatomical differences between an<br />

Oriental and Occidental eyelid be appreciated so that unique features <strong>of</strong> the<br />

Asian eyelid are preserved. Careful pre-operative assessment <strong>of</strong> the patient›s<br />

eyelid anatomy and associated pathology is mandatory. The treatment should<br />

be customised to correct the underlying problems and cater to the patient›s<br />

expectations. Suture blepharoplasty may not always achieve a long lasting or<br />

effective result in some patients.<br />

IS-OCP-MO 356 (2)<br />

Managing the Epicanthal Fold: Considerations and Techniques<br />

Tomoyuki Kashima (1)<br />

1. Gunma University<br />

Recurrence <strong>of</strong> lash globe contact after surgical correction for epiblepharon with<br />

co-existing epicanthic fold had been reported to be high. Prominent epicanthic<br />

folds would aggravate the rolling-in <strong>of</strong> cilia. We used the Uchida›s method for<br />

epicanthoplasty in Down›s syndrome and Z-plasty for severe epiblepharon,<br />

and combining with the modified Hotz procedure as epiblepharoplasty, and<br />

had achieved successful surgical outcomes. Skin incision is to be carefully<br />

planned and so is meticulous- tissue manipulation, so as to minimize the risks<br />

<strong>of</strong> unsightly cutaneous scarring post operation.<br />

IS-OCP-MO 356 (3)<br />

Surgical Pearls in the Treatment <strong>of</strong> Cicatricial Entropion<br />

Dong-Mei Li (1)<br />

1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University<br />

Retrospectively evaluate 34 cases with cicatrical entropin. The Hotz tarsotomy<br />

is used in cases <strong>of</strong> entropion caused by thickening and distortion <strong>of</strong> tarsus, and<br />

gray-line incision was combined to correct the severe entropion or with topical<br />

misdirection <strong>of</strong> the eyelashes, some grafts were implanted into dissected grayline.<br />

In patients caused by tarsocojunctival shortening, the involved tarsus<br />

replaced by autogenous tarsocojunctival grafts or allogeneic scleral grafts are<br />

curative. Tarsotomy combined everting sutures allows the eyelids positions<br />

stabilized in the entropion caused by topical cicatricial traction.<br />

IS-OCP-MO 356 (4)<br />

Optimising the Success <strong>of</strong> Congenital Ptosis Surgery<br />

Seah Lay-Leng (1)<br />

1. Singapore National Eye Centre<br />

Long-term success in functional and cosmetic improvements, following<br />

Congenital Ptosis repair, are important for both patients and surgeons. To<br />

achieve a desired post-operative outcome, it is crucial to ensure: accurate preoperative<br />

assessment, appropriate choice <strong>of</strong> procedures, meticulous tissue<br />

dissection, accurate lid height adjustment, and a good post-operative care. A<br />

thorough pre-operative counseling to manage patients’ expectations, involving<br />

communicating the limitations and risks <strong>of</strong> surgery, are to be undertaken. Any<br />

co-existing strabismus, refractive error and amblyopia should be treated early.

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