Table of Contents - WOC 2012

WOC2012 Abstract Book
PO-RET-157
Young patients under 30 years old with central retinal vein occlusion
Watanabe Hiroshi (1) , Suzuki Yuka (1) , Tanaka Kumiko (1) , Kumashiro Syun (1) ,
Tochikubo Tetuo (1)
1. Toho University Omori Medical Center
PURPOSE: Central retinal vein occlusion (CRVO) is commonly encountered in
older patients with vascular disease. We report CRVO in under 30years old
patients. CASES: A male and three females (21 ~ 29 years old). Observation
period was 6 ~42 months. At the first visit, all patients underwent a detailed
ophthalmic and medical history and a comprehensive ophthalmic evaluation
.Ophthalmic examination revealed non-ischemic CRVO. All patients had no
systemic disease like diabetes, hypertension, and hyperlipidemia; a patient had
chronic renal failure. Laboratory studies including anti-neutrophilic cytoplasmic
antibody (ANCA) and anticardiolipin immunoglobulin G and immunoglobulin
M antibodies were preformed in all cases, but no abnormal finding was seen.
As all cases were getting worse slowly, fibrinolysis therapyEintravenous drop
of steroid were performed. Additional therapy of photocoagulation for turned
worse ischemic CRVO and anti-VEGF therapy for macular edema. Final visual
acuity of three cases was over (0.7) and a case with chronic renal failure was
under (0.1).
Conclusion: Three cases with no clear risk factors had good visual acuity, but
a case with systemic disease like chronic renal failure had poor visual acuity in
under 30 years old patients with CRVO.
PO-RET-158
Time course of changes in aqueous flare intensity after vitrectomy
for proliferative diabetic retinopathy
Hoshi Sujin (1) , Okamoto Fumiki (1) , Hasegawa Yumi (1) , Sugiura Yoshimi (1) ,
Oshika Tetsuro (1)
1. Department of Ophthalmology, Institute of Clinical Medicine, Tsukuba University
purpose: To investigate the changes in aqueous flare intensity (AFI) after
vitrectomy for proliferative diabetic retinopathy (PDR) and to determine the
clinical factors related to an increase in AFI.
Methods: This study included 74 eyes with PDR undergoing primary vitrectomy.
AFI was measured preoperatively and at 1, 2 weeks, 1, 3, and 6 months
postoperatively using the laser flare meter. Clinical data were collected,
including age, fasting serum glucose, glycatedhemoglobin, severity of PDR,
presence of iris neovascularization, administration of hemodialysis therapy,
number of photocoagulation, operation time, performance of combined cataract
surgery, occurrence of postoperative vitreous hemorrhage, occurrence of
postoperative fibrin formation.
Results: Vitrectomy increased AFI, and the peak was observed at the first
postoperative week. AFI decreased to a stable level at 3 months postoperatively,
but remained significantly higher than that of preoperative eyes throughout the
observation period. Multiple regression analysis revealed that AFI at 3 months
postoperatively had significant correlation with the preoperative AFI, number of
photocoagulation, and operation time.
Conclusion: AFI after vitrectomy for PDR returned to a stable level 3 months
postoperatively, but remained significantly higher than the normal level. The
degree of preoperative blood-aqueous barrier disruption and surgical invasion
were associated with the increase in AFI.
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PO-RET-159
Changes in Intraoperative Intraocular Pressure During 20-gauge Pars
Plana Vitrectomy Using the Vented Gas Forced Infusion System
Sugiura Yoshimi (1) , Okamoto Fumiki (1) , Okamoto Yoshifumi (1) , Hiraoka Takahiro
(1) , Oshika Tetsuro (1)
1. Department of Ophthalmology, Institute of Clinical Medicine, University of
Tsuku
Purpose: To measure changes in intraoperative intraocular pressure (IOP)
during 20-gauge pars plana vitrectomy using the Vented Gas Forced Infusion
(VGFI) system, and to investigate IOP fluctuations during various vitrectomy
manipulations.
Methods: In porcine eyes, after core vitrectomy was performed using 20-gauge
system, by The IOP fluctuations were recorded during various surgical
manipulations, including vitreous cutting, aspiration, and scleral compression.
Results: It took 0.8 sec for IOP to rise from 30 to 60 mmHg when the VGFI
setting was changed, and 3.9 sec to drop from 30 to 10 mmHg. By vitreous
cutting with aspiration pressure of 200 mmHg and 300 mmHg, IOP decreased
from 30 to 13.7 mmHg in 0.9 sec, and to 8.3 mmHg in 1.9 sec. By aspiration
with 200 mmHg pressure, IOP decreased from 30 to 0 mmHg in 3.0 sec.
Scleral compression without aspiration rapidly increased IOP to 90.9 mmHg
and release of compression decreased IOP to 3.9 mmHg in 0.2 sec.
Conclusion: IOP fluctuations were assessed during 20-gauge vitrectomy with
the VGFI system. There was a considerable time lag between the timing
of VGFI setting change and actual IOP change. Vitrectomy manipulations
induced significant and varied amount of fluctuations in IOP.
PO-RET-160
Analysis on the correlative factors and therapeutic efficacy of
secondary high intraocular pressure after vitreoretinal surgery for
proliferative diabetic retinopathy
Chen Song (1) , Meng Li-Zhu (1)
1. Tianjin Eye Hospital
Objective To discuss the correlative factors and therapeutic efficacy of
secondary high intraocular pressure(IOP) after vitreoretinal surgery (VRS)for
proliferative diabetic retinopathy PDR Methods 161 eyes of 136 consecutive
patients with type 2 PDR were analyzed retrospectively. The IOP, retinal
anatomic reattachment and best-corrected visual acuity(BCVA) were
observed.Multivariate analysis with logistic regression was used to determine
the influencing factors of high IOP after VRS.Results Forty-three eyes of 43
patients experienced postoperative high IOP, with the incidence of 26.7%%
(43/161). Multivariate logistic regression revealed postoperative inflammatory
reaction (OR=3.027) and fasting blood glucose(FBG) (OR=2.866)were two
independent risk factors to lead to high IOP. However, it was not related to
the practice of intraocular tamponade, the combined performance of crystal
surgery and scleral buckle. Conclusion The visual prognosis may be evaluated
via the preoperative natural factors and post-operative complications. This
study also revealed the recurrence of RD and optic nerve atrophy were two
independent risk factors in poor BCVA