Table of Contents - WOC 2012

IS-TEC-FR 139 (2)
Future Therapeutic Modalities for Corneal Endothelial Dysfunction
Kinoshita Shigeru (1)
1. Kyoto Prefectural University of Medicine
Abstract not available
IS-TEC-FR 139 (3)
Confocal Microscopy for Assessing Ocular Surface Inflammation
Baudouin Christophe (1)
1. Quinze-Vingts Hospital
The recently developed in vivo confocal microscopy technologies may provide
in a noninvasive way excellent histologic-like patterns of the ocular surface
structures, showing high-resolution images of the corneal, limbal and
conjunctival epithelia, dendritic cells, new blood vessels, and in specific
indications some infectious agents. Many ocular surface diseases may find
important applications, such as dry eye, allergy, refractive surgery, glaucoma,
infections, corneal neovascularization or limbic pathologies. This technology
could thus become a new routine method to explore ocular surface disorders.
IS-TEC-FR 139 (4)
High Resolution Imaging of the Trabecular Outflow System
Castillejos Alfredo (1)
1. NYEEI / HOL / CPO
Due to technical difficulties of histological studies and the limited resolution of
previous imaging technologies; the main outflow route, the trabecular pathway,
remains poorly understood as a unit. We developed a new imaging technique
using high definition anterior segment Fourier-domain OCT that combines
radial and tangential scans allowing clear visualization and in vivo evaluation
of all the microstructures comprising the trabecular pathway in normal and
glaucomatous eyes. A brief review of the latest imaging modalities is also
discussed.
The Impact of Aging: The Changing Epidemiology of Vision Loss
Fri 17 Feb 15:30 - 17:00 Conference Room A4
IS-EPI-FR 140 (1)
Progress in Technology for Changing Epidemiology - SdOCT and
AMD Classification
Kaluzny Jakub, Sikorski Bartosz L., Burduk Mateusz
1. Collegium Medicum, Nicolaus Copernicus, University
Macular degeneration is a common problem of the ageing population.
Concerning the use of Spectral domain Optical Coherence Tomography
(SdOCT) in clinical practice it seems reasonable to find new classification
of choroidal neowascularisation (CNV) associated with age-related macular
degeneration (AMD) based on SdOCT image. The purpose of the study is to
divide CNV according to characteristic features in SdOCT examination and to
correlate this classification with fluorescein angiography, and eventually help
the diagnostics in the future. In 89 eyes with CNV of diameter not exciding
2 DD fluorescein angiography and SdOCT were performed. All eyes were
divided according to position of CNV in respect to retinal pigment epithelium
(RPE) and localization of exudates. These results were correlated with
traditional classification based on fluorescein angiography. The most common
abnormality in SdOCT was CNV under RPE regardless the type of CNV in
fluorescein angiography. In eyes with classic component the CNV over
RPE was reported in 94 % of eyes. The SdOCT can reduce the number of
fluorescein angiographies in patients with AMD. However due to only good
level of correlation this examination cannot be completely replaced by SdOCT
at the current stage.
IS-EPI-FR 140 (2)
Is it Cost-Efficient to Treat AMD in Developing Countries?
Lansingh Van (1)
1. IAPB
WOC2012 Abstract Book
AMD is increasing with the aging of the world’s population; this is particularly
true in developing countries. The most effective treatment for neovascular AMD
is intravitreal injection of anti-VEGF agents. Economic analysis in developed
countries has shown a wide variation with cost-utility studies of ranibizumab
often showing an unacceptable cost per QALY. However, we are lacking longterm
efficacy and safety data for accurate modeling over 5-20 years.
IS-EPI-FR 140 (3)
Changing Epidemiology of Posterior Segment Eye Diseases in
Africans
Mathenge Ciku (1)
1. Fred Hollows Foundation
Posterior segment eye diseases (PSED), the leading causes of blindness in
high-income countries are becoming more common in Africa. This presentation
provides evidence from one of the largest population based studies in Africa,
of the high prevalence and impact on vision of AMD, diabetic retinopathy and
glaucoma in Africans. PSED present a double burden on African communities
and eye services that are yet to control anterior segment diseases. This data is
useful for planning and designing intervention strategies in Africa.
IS-EPI-FR 140 (4)
Presbyopia - Is This Really a Vision Loss?
Radu Simona
1. EURO-OPTICS
Presbyopia is a part of the natural aging process. Despite modern investigation
techniques, presbyopia›s exact mechanisms are not known with certainty; the
research evidence supports a loss of elasticity of the crystalline lens, changes
in the lens›s curvature and axial thickness and also in the ciliary body. Although
presbyopia is not defined as a life- or vision threatening condition, the different
options available (spectacles, contact lenses, surgery) for restoring near-vision
may also decrease the quality of distance vision, as well as stereopsis.
IS-EPI-FR 140 (5)
Tear Film and Quality of Vision in Aging Subjects
Grupcheva Christina
1. Medical University and Specialised Eye Hospital
Dry eye is a common ophthalmic problem of the ageing population. Discomfort
and decreased visual quality are the most disturbing symptoms. Both of those
are associated with significantly decreased quality of life. Regardless of the
high incidence and penetrance in the ageing population today we have no
universal diagnostic method. There are many methods to evaluate and
diagnose dryness, however, most of them are difficult on application to the busy
clinic, some are very expensive, and majority are very difficult to standardize.
Following diagnosis, the practitioner must select a proper therapeutic regimen.
The most commonly used medications are tear film substitutes. They may be
drops, gels and even spray. Recently some peroral medications are also used.
The second line measures are to prevent drainage by temporary or permanent
punctual occlusion. In evaporative dry eye one of the most important treatment
modality is lid hygiene. To treat dry eye practitioner must be familiar with all
diagnostic methods, apply them properly, identify the underlying reason(s)
for dry eye and treat the condition with the best possible therapy. Treatment
should be titrated individually, as dry eye is dependent on many environmental,
biological and other factors. One of the most important factors is ageing.
IS-EPI-FR 140 (6)
Changing Epidemiology of Vision Loss in Children and its Life
Impact
Aclimandos Wagih (1)
1. King›s College Hospital, Royal College of Ophthalmologists
The causes of visual impairment amongst children in various parts of the world
will be presented and compared. Changing patterns will be highlighted. The
impact of visual loss on children at various stages of their development will be
discussed. The potential implications on the child›s interaction with society at
large and their families in particular will be analysed. The general management
of children with visual impairment and recommendations for few specific
conditions will be discussed.
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