Table of Contents - WOC 2012

FP-ONC-MO 404 (9)
Plaque Therapy for Ocular Tumors: Middle East - Single Institute
Preliminary Results
Jaradat Imad (1) , Mula-Hussain Layth (2) , Wadi-Ramahi Shada (1) , Mehyar
Mustafa (1) , Nawaiseh Ibrahim (1)
1. King Hussein Cancer Center
2. University of Mosul, College of Medicine
Purpose: To analyze the three years experience and results of the Plaque
Therapy (PT) in Ocular Tumors (OT) at single institute (King Hussein Cancer
Center-KHCC-) in a developing country (Jordan) from the Middle East region.
Methods: A review of our early results of PT service at KHCC.
Results: During Mar. 2008 till Nov. 2010, the team did twelve procedures for
different cases of OT; 25% Retinoblastoma in children and 75% Choroidal
Melanoma in adults, treated with a prescribed dose of 4400cGy and 8500cGy
respectively, 75% were Jordanian and 25% were from neighboring countries.
The 2-years eye preservation rate was (92%), dose to optic disk and to macula
were inversely related to the distance between the tumor edge and the optic
disk and the macula (P=0.012 and 0.006; respectively).
Conclusions: PT was successfully implemented at KHCC and this service can
be applied easily in other developing countries. This service helped our national
patients and those from neighboring countries. Close integration with other
advanced programs is mandatory for this implementation in order to safely and
correctly transfer this technology. Our preliminary results were encouraging
and were similar to other programs worldwide.
FP-ONC-MO 404 (10)
No Chlamydiae or Helicobacter Pylori is Detectable in a Cohort of
Chinese Patients with Conjunctival MALT Lymphoma
Cai Jiping (1)
1. Department of Ophthalmology, Shanghai Changzheng Hospital, Second
Medical University
Purpose: To detect microbial pathogens in conjunctival mucosa-associated
lymphoid tissue (MALT) lymphoma specimens in an attempt to find out possible
associations between conjunctival MALT lymphoma and microbial infections.
Methods: Using the PCR technique, freshly obtained tumor specimens from
16 cases of conjunctival MALT lymphoma as confirmed by postoperative
pathology were detected for DNA of Chlamydia psittaci (Cp), Chlamydia
trachomatis (Ct), Chlamydia pneumoniae (Cpn) and Helicobacter pylori (Hp).
Synthetic Cp, Ct, Cpn and Hp DNAs were used as positive control, and blank
plasmid DNA as negative control.
Results: Electrophoresis showed that no bands corresponding to the positive
control were observed in the specimens, indicating that no DNA of the four
microbials was detected in the specimens of the 16 cases of conjunctival MALT
lymphoma.
Conclusion: The PCR technique was able to detect the positive control quickly
and accurately, but the results of PCR in detecting the 16 specimens were
negative, indicating that there is no association between conjunctival MALT
lymphoma and the four microbials in Chinese patients.
FP-ONC-MO 404 (11)
Brachytherapy for Ocular Melanoma During Pregnancy
Aljamal Rana›a (1) , Kaleeva Elvera (1) , Kivelä Tero (1)
WOC2012 Abstract Book
1. Helsinki University Central Hospital, Department of Ophthalmology
Objective: To report the outcome of brachytherapy for uveal melanoma during
pregnancy.
Methods: A case report of two white females aged 21 and 26 years, who
presented during their 15th and 22nd week of gestation with choroidal
melanoma, respectively. B-scan ultrasonography showed a tumor 8.5 and 10.1
mm in height and 12.3 and 14.1 mm in diameter, respectively, there was no
extraocular extension. Iodine brachytherapy of 80 and 70 Gy was delivered in
138 and 266 hours, respectively.
Results: The fetal doze in the first case was estimated to be 1-2 mSv by the
National Radiation Safety Authority. In the second case the plaque was
irradiating directly away from the fetus and the fetal dose was close to nil.
One patient delivered a full-term normal baby, the other twins. Both choroidal
melanomas responded well and one year after treatment tumor height was 5.8
mm and 4.6 mm, respectively. However, both patients later developed liver
metastasis and one subsequently died of progressive metastasis. No local
tumor recurrence has taken place.
Conclusion: Brachytherapy of selected tumors is safe to the fetus, provided
that calculation of the fetal dose is done.
Free Paper: New Technology and Alternative Medicine
Mon 20 Feb 13:30 - 15:00 Conference Room B2
FP-TEC-MO 405 (1)
Prognostic Factor Analysis in Vitreoretinal Surgery for Retinal
Detachment Attributable to Macular Hole in High Myopia
Chen Song (1) , Xu Yan (1)
1. Tianjin Eye Hospital
2. Tianjin Eye Hospital
Objective: To detect the prognostic factors associated with initial reattachment
after vitreoretinal surgery for retinal detachment attributable to macular hole
(MHRD) in high myopia.
Methods: This study included 85 eyes of 84 patients with MHRD in high
myopia (diopter more than -8.0 or axial length more than 26.0mm). We
performed multivariate logistic regression analysis to assess the influence of
each preoperative factor on initial success.
Results: Success rate of initial reattachment was 83.53%. Postoperative bestcorrected
visual acuity (BCVA) of 71 eyes with initial success was significantly
better than those of 14 eyes with initial failure (P