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Table of Contents - WOC 2012

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<strong>WOC</strong><strong>2012</strong> Abstract Book<br />

PO-RET-175<br />

Hospitalized patients with endogenous MRSA endophthalmitis and<br />

unable to undergo vitrectomy may achieve a good outcome with<br />

bedside intravitreal antibiotic injection alone<br />

DAHR SAM (1)<br />

1. RETINA CENTER OFOKLAHOMA<br />

Purpose: to demonstrate that severely ill hospitalized patients with endogenous<br />

methicillin resistant staphylococcus aureus (MRSA) endophthalmitis may<br />

achieve a good outcome with bedside therapy alone.<br />

Methods: interventional case series.<br />

Results: Three patients (ages 52, 63, and 64) presented with culture proven<br />

MRSA bacteremia and endogenous endophthalmitis. Two patients presented<br />

unilaterally and one patient presented bilaterally. The unilateral patients were<br />

treated with intravitreal antibiotic injection alone and the infection subsequently<br />

cleared. The bilateral patient was treated in one eye with vitrectomy and in the<br />

other eye with antibiotic injection alone; both eyes cleared but the vitrectomized<br />

eye subsequently developed a retinal detachment.<br />

Conclusion: Endogenous MRSA endophthalmitis may develop in patients with<br />

MRSA bacteremia. These patients may be too ill to undergo vitrectomy or<br />

vitrectomy may be unavailable at the facility. These patients may still achieve<br />

good outcomes with intravitreal antibiotic injection alone.<br />

PO-RET-176<br />

Incidence <strong>of</strong> posterior synechia after pars plana vitrectomy for<br />

vitreoretinal disorders<br />

Okamoto Yoshifumi (1) , Okamoto Fumiki (1) , Minamikawa Yuka (1) , Oshika<br />

Tetsuro (1)<br />

1. Department <strong>of</strong> Ophthalmology, Institute <strong>of</strong> Clinical Medicine, Univ. <strong>of</strong> Tsukuba<br />

Purpose The development <strong>of</strong> posterior synechia <strong>of</strong> the iris interferes with<br />

postoperative visualization <strong>of</strong> the retina and patients› visual function. We<br />

examined factors influencing the development <strong>of</strong> posterior synechia after pars<br />

plana vitrectomy (PPV) for vitreoretinal disorders. Methods We retrospectively<br />

reviewed the records <strong>of</strong> 421 eyes <strong>of</strong> 356 patients who received PPV by the<br />

same surgeon for vitreoretinal disorders. The frequency <strong>of</strong> posterior synechia<br />

was assessed, and multivariate analysis was performed to investigate the<br />

relationship between various explanatory factors and the development <strong>of</strong><br />

posterior synechia. Explanatory factors included age, sex, operating time,<br />

combined cataract surgery, gauge <strong>of</strong> vitrectomy system, performance <strong>of</strong> scleral<br />

compression, number <strong>of</strong> laser photocoagulation, usage <strong>of</strong> gas tamponade,<br />

steroid, and atropine ointment, postoperative factors (existence <strong>of</strong> vitreous<br />

hemorrhage, anterior chamber fibrin, and hyphema). Results Posterior<br />

synechia was found in 10.7% (45 <strong>of</strong> 421 eyes), and patients with proliferative<br />

diabetic retinopathy showed the highest incidence (16.8%). The explanatory<br />

factors associated with posterior synechia were operating time and number <strong>of</strong><br />

laser photocoagulation. Conclusion The incidence <strong>of</strong> posterior synechia after<br />

PPV may be reduced by minimizing the degree <strong>of</strong> operative invasion to the<br />

eye.<br />

642<br />

PO-RET-177<br />

Role <strong>of</strong> intravitreal bevacizumab administrated preoperatively in<br />

patients with proliferative diabetic retinopathy<br />

Josifova Tatjana (1) , Henrich Paul Bernhard (1) , Guber Josef (1)<br />

1. University Hospital, Eye Clinic<br />

Purpose: To evaluate the efficiency and safety <strong>of</strong> 3 and 5-7 days preoperative<br />

intravitreal bevacizumab administration in patients with proliferative diabetic<br />

retinopathy (PDR).<br />

Methods: Retrospective study for PDR patients who underwent 20 and 23G.<br />

pars plana vitrectomy (ppv). Bevacizumab (1.25 mg/0,05 ml) was injected 3<br />

days preoperatively in Group A (12 patients) and 5-7 days preoperatively in<br />

Group B (14 patients). Both groups were matched for: age, diagnosis, systemic<br />

diseases and underwent preoperative systematic controls.<br />

Results: Vitreous haemorrhage (VH) during the operation in Group A was<br />

present in 3/12 patients ( 25% ) while in Group B none <strong>of</strong> the patients showed<br />

VH. First week postoperative VH in Group A was noted in 3 patients compared<br />

to Group B with 2 patients. No retinal detachment as a complication after<br />

bevacizumab administration was observed.<br />

Conclusion: Preoperative intravitreal injection <strong>of</strong> bevacizumab appears to be<br />

safe and effective way <strong>of</strong> reducing the incidence <strong>of</strong> intraoperative and early<br />

postoperative VH. Although the study includes small group <strong>of</strong> patients and with<br />

no significant difference between the groups we still encourage bevacizumab<br />

administration between 5-7 days, preoperatively. Further randomised studies<br />

should be performed to evaluate the optimal timing <strong>of</strong> preoperative drug<br />

administration.<br />

PO-RET-178<br />

Non sclerotomy silicone oil removal-a pilot study<br />

Deka Satyen, Bhattacharjee Harsha, Barman Manab, Das Shrutanjoy,<br />

Saibum Ronel<br />

1. Sri Sankaradeva Nethralaya<br />

AIM: Efficacy and safety <strong>of</strong> non sclerotomy transpupillary Silicone Oil Removal<br />

(SOR) and combined phacoemulsification.<br />

Methods: In this pilot study (January- May 2010) five eyes <strong>of</strong> four candidate<br />

patients for SOR and cataract extraction underwent transpupillary<br />

removal <strong>of</strong> silicone oil through planned posterior capsular opening after<br />

phacoemulsification. No sclerotomy was made and the anterior chamber<br />

canula was used for intraocular infusion. Intraocular lens implanted at the end<br />

<strong>of</strong> SOR and patients were followed up for 6 months. RESULTS All patients had<br />

a favorable surgical outcome with attached retina postoperatively without any<br />

complication.<br />

Conclusion: This is an effective and safe technique that <strong>of</strong>fers the main<br />

advantage <strong>of</strong> diminished surgical trauma.<br />

PO-RET-179<br />

Multiple subretinal cysticercosis: a case report<br />

Singh Bhupesh, Majji Ajit Babu<br />

1. LV PRASAD EYE INSTITUTE<br />

Purpose: To report a rare case <strong>of</strong> multiple subretinal cysticercosis Method: A<br />

26-year-young male presented with complaints <strong>of</strong> decreased vision in the<br />

right eye since 20 days. Visual acuity <strong>of</strong> right eye was perception <strong>of</strong> light with<br />

accurate projection <strong>of</strong> rays and in the left eye was 20/20. Right eye anterior<br />

segment was within normal limits and dilated fundus examination showed<br />

localized retinal detachment with two large subretinal cysts measuring 5x6<br />

mm with spontaneous movements on exposure to light. Clinical diagnosis <strong>of</strong><br />

subretinal multiple cysticercosis in right eye was made. B-scan <strong>of</strong> the right<br />

eye showed two cysts with hyperechoic foci within the cyst suggestive <strong>of</strong><br />

scolex <strong>of</strong> cysticercosis. CT scan <strong>of</strong> head and orbit ruled out the presence <strong>of</strong><br />

neurocysticercosis. A standard 3 port 20G pars plana vitrectomy with cyst<br />

removal was performed. Histopathology showed the parasite with 3 layers <strong>of</strong><br />

cuticle and protoscolex with a branching body cavity confirming the morphology<br />

<strong>of</strong> Cysticercus.<br />

Result: There was no significant improvement in the visual acuity due to<br />

extensive scarring in macular area.<br />

Conclusion: Multiple subretinal cysticercosis can be present and should be<br />

kept in mind. Visual outcome depends upon cyst location and secondary<br />

scarring.

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