Table of Contents - WOC 2012

WOC2012 Abstract Book
Resistance.
FP-COR-SU 268 (2)
Cisternoplasty, The Easiest Surgical Technique to Improve Patients
with Dry Eye
Murube Juan (1)
1. University of Alcala
Objective: The surfocular cistern is the anatomical and functional space
located in the lateral canthus of the eyelids. Its main function is to retain tears
for distribution along the lower lid meniscus and ocular surface when blinking.
To increase the lacrimal cistern (cisternoplasty) is an easy means of allowing it
to retain larger quantities of natural tears and substitutive collyria.
Methods: The lacrimal cistern may be enlarged with various techniques: 1.A
cutaneous flap may be constructed to cover the antero-lateral part of the natural
cistern, 2. A lamellar flap of the lateral lid rim may be rotated externalizing it,
3.Tarsal tissue of the upper lid in the lateral canthus may be removed, or 4.
Combinations of these techniques may be used.
Results: A drop of artificial tears contains about 30 µ l of fluid. The lacrimal
basin (between lids and ocular surface) usually only admits about 8 µ l.
Therefore a drop of artificial tear is overflowed in about 5 minutes, when the
lacrimal basin recovers its normal 8 µ l volume. A cisternoplasty may increase
the volume of the lacrimal cistern up to 20-25 l. This increased volume of liquid
retention maintains the effect of the natural or artificial tears up to six times
longer.
Conclusion: Cisternoplasty is an easy and short surgery that benefits the state
of patients with dry eyes.
FP-COR-SU 268 (3)
Comparison of Role of Voriconazole and Natamycin in Management
of Fungal Keratitis
Saha Suman (1) , Sengupta Jayangshu (2) , Banerjee Debdulal (3) , Khetan
Archana (2)
1. Ocular Microbiology Division, Priyamvada Birla Aravind Eye Hospital
2. Cornea Clinic, Priyamvada Birla Aravind Eye Hospital
3. Department of Microbiology, Vidyasagar University
Objective: To compare the effects of voriconazole 2% with natamycin 5%
eyedrops for topical monotherapy of fungal keratitis.
Methods: This is a retrospective comparative case series involving patients
with culture positive fungal keratitis between April 2008 and March 2010. 144
eyes were selected for analysis. Two groups were identified- Group 1 (66 eyes)
receiving Voriconazole (2%) and Group 2 (78 eyes) receiving Natamycin (5%).
The groups were analyzed for cure rate, treatment failure and time to complete
healing.
Results: 39 cases (59.09%) in Group 1 including Aspergillus sp (37.87%),
Fusarium sp (7.57%), Demateceous (6% ), Penicillium sp (3.03%) and
unidentified sp (4.54%) showed healing with corneal scar formation. Similar
response was obtained in 40 cases (51.28%) in Group 2 including Aspergillus
sp (34.61% %), Fusarium sp (12.82 %) and Demateceous (3.84%). Among the
non responders, Group 1 consisted of Aspergillus sp (7.57%), Fusarium sp
(10.6%) Demateceous (3%), Penicillium (2cases) and Candida(16.6%) while
Group 2 included Aspergillus sp 17.9% Fusarium sp 20.5% and Demateceous
in 10.25%. Mean resolution time in Group 1was 34.31 days and in Group 2
was 44.31 days.
Conclusion: Voriconazole has promising activity against filamentous fungi and
may prove useful in the management of fungal keratitis.
260
FP-COR-SU 268 (4)
Microbial Keratitis After Manual Descemet Stripping Endothelial
Keratoplasty
Saha Suman (1) , Sengupta Jayangshu (2) , Khetan Archana (2) ,
Banerjee Debdulal (3)
1. Ocular Microbiology Division, Priyamvada Birla Aravind Eye Hospital
2. Cornea Clinic, Priyamvada Birla Aravind Eye Hospital
3. Department of Microbiology, Vidyasagar University
Objective: To report cases of infective keratitis following Descemet Stripping
Endothelial Keratoplasty (DSEK).
Methods: One hundred thirteen eyes that had undergone DSEK between
March 2008 to February 2011 were retrospectively analyzed for the occurrence
of infectious keratitis. 6 cases were identified and included in this study. All
patients had a detailed clinical evaluation followed by corneal scraping. The
scraping material was sent for detail microbiology workup. The initial medical
treatment was based on microbiology report with appropriate topical antibiotics.
Results: The incidence of infectious keratitis following DSEK was 5.3%. All the
six eyes developed bacterial keratitis with isolation of Pseudomonas aeruginosa
in 4 patients and Staphylococcus aureus in 2 patients. All the cases developed
within the first 3 months of surgery. The most significant predisposing factor
was use of bandage contact lens and abnormal lid hygiene. Complete
resolution of infection occurred in all the cases; however the graft failed in 2
cases necessitating conventional full thickness keratoplasty.
Conclusion: Infective keratitis following DSEK is rare but can lead to graft
failure. Postoperative control of risk factors and early recognition of infectious
complications may decrease the incidence of severe microbial keratitis after
DSEK.
FP-COR-SU 268 (5)
Pathogenetic Aspects of Crystalline Keratipathy After Re-
Keratoplasty
Shamurat Amansakhatov (1) , Larisa Shetinina (1) , Maya Zhutdieva (1)
1. Ministry of Health Care
Purpose: To study the mechanism of crystalline keratopathy development after
re-keratoplasty.
Methods: Within the period since 2006 till 2010, in 3 patients, after rekeratoplasty,
we observed the development of crystalline keratopathy. For
differential diagnosis of pathologic deposits in transplantat crystallographic
analyses(CA), crystallochemical analyses (CCA) as well as spectrophotometric
analyses (SPA) of fragments from the surface layers of the transplantat and
crystallized lacrimal liquid(LL) has been carried out.
Results: CA of the material having got out from the surface layers of the
transplantat showed, that there are crystal-like structures of abnormal form
different size and dissimilar by the ability to make the light out. CA, CCA
and SPA of the material investigated, taken from the surface layers of the
transplantat show the absence of true crystals in crystalline edge, which is
considered to be the main structural element.
Conclusion: So, CA, CCA and SPA of the material investigated showed the
existence of cholesterin ethers and lypoproteids’ high ratio in crystals and
lacrimal liquid.