Table of Contents - WOC 2012

PO-RET-152
Comparison of internal limiting membrane peeling with and without
indocyanine green during vitrectomy for idiopathic macular holes - Is
indocyanine green harmless? -
Ishida Masahiro (1) , Ichikawa Yoshikazu (1) , Ishikawa Atsushi (1) , Imamura
Yutaka (1) , Takeuchi Shinobu (2)
1. Teikyo University Mizonokuchi Hospital
2. Takeuchi Eye Clinic
Purpose: To compare surgical results of vitrectomy for idiopathic macular hole
1) without internal limiting membrane (ILM) peeling, 2) with ILM peeling using
indocyanine green (ICG), and 3) with ILM peeling without the use of any dyes.
Methods: One hundred eyes of 97 patients with idiopathic macular hole with at
least 1 year follow-up after vitrectomy were examined retrospectively. Surgical
procedures were divided into three groups: 1) vitrectomy without ILM peeling
(ILM-, n=8), 2) vitrectyomy with ILM peeling with ICG (ILM+ICG+, n=19), and
3) vitrectomy with ILM peeling without any dyes (ILM+ICG-, n=73).
Results: Initial and final anatomical macular hole closure was obtained in
75%/100% (initial/final) in ILM-, 89%/100% in ILM+ICG+, and 99%/99% in
ILM+ICG-. There was a significant difference in initial hole closure rate between
ILM- and ILM+ICG- (p=0.025). Best postoperative visual acuity of 1.0 or better
was obtained 50% in ILM-, 31% in ILM+ICG+, and 59% in ILM+ICG-. This rate
was significantly higher in ILM+ICG- than ILM+ICG+ (p=0.031).
Conclusion: ILM peeling without ICG was associated with higher initial closure
rates than the vitrectomy without ILM peeling. ILM peeling without ICG was
associated with better postoperative visual acuity than ILM peeling with ICG.
PO-RET-153
Carotid Artery Echo grapy in Neovascular Glaucoma Complicated
with Proliferative Diabetic Retinopathy
Watanabe Hiroshi (1) , Ooi Aya (1) , Yamazaki Nanae (1) , Tochikubo Tetsuo (1)
1. Toho University Omori medical center
Purpose: There is case that only one eye develops in neovascular glaucoma
complicated with proliferative diabetic retinopathy that the photocoagulation
and vitreous surgery were performed in the same way to the both eyes .To
evaluate the carotid artery disease and the association with NVG onset.
Method: 13 cases that only one eye developed NVG complicated with PDR
that was treated in the same way to both eyes.Carotid artery intima-media
thickness (IMT) and plaque score (PS) were measured using ultrasonic
diagnostic equipment XG (Toshiba).
Results: IMT of onset eyes and non-onset eyes was 2.1 ± 0.9,1.8 +-0.6, and, in
the PS, 4.1+-1.6mm, 3.6+-1.6 and a vascular disorder risk tended to be high.
Conclusions: It was suggested that carotid artery disease was associate with
the onset of NVG complicated with PDR and carefully follow up is necessary
for NVG onset in strong carotid artery disease.
PO-RET-154
Photodynamic therapy combined with intravitreal injection of
ranibizumab for naive polypoidal choroidal vasculopathy
Nemoto Rey (1) , Miura Masahiro (1) , Tsukahara Rintaro (1) , Iwasaki Takuya (1) ,
Goto Hiroshi (2)
1. Ophthalmology Tokyo medical university ibaraki medical center
2. Ophthalmology Tokyo medical university
Purpose: To evaluate the efficacy of combined verteporfin photodynamic
therapy (PDT) with intravitreal injection of ranibizumab (IVR) for the treatment
of naïve polypoidal choroidal vasculopathy (PCV).
Methods: Prospective, non-comparative, consecutive case series study.
Twenty five eyes of 25 patients (mean 74.2±7.4 years) with naïve PCV were
treated with PDT combined with IVR. Patients were followed 12 months with
best-corrected visual acuity (BCVA) in ETDRS letters and central retinal
thickness (micrometer).
Results: The mean BCVA were 46±21 letters at baseline, 49±28 letters at
Month 3, 48±29 letters at Month 6, and 45±29 letters at Month 12. Central
retinal thickness reduced from 250±117 at baseline to 145±78 at Month 3 (P =
0.0001), 150±80 at Month 6 (P = 0.001), and 166±94 at Month 12 (P =0.005).
The mean number of IVR and PDT were 4.5 and 1.2, respectively.
Conclusions: Combined PDT and IVR maintained visual acuity and reduced
CRT at 12 months.
WOC2012 Abstract Book
PO-RET-155
Changes in Visual Function Following Surgery for Macula-on Retinal
Detachment
Okamoto Fumiki (1) , Sugiura Yoshimi (1) , Okamoto Yoshifumi (1) , Hiraoka Takahiro
(1) , Oshika Tetsuro (1)
1. Department of Ophthalmology, Institute of Clinical Medicine, University of
Tsuku
Purpose: To evaluate the changes in contrast sensitivity (CS) following surgery
for macula-on rhegmatogenous retinal detachment (RD).
Methods: This study included 65 eyes of 65 patients with unilateral macula-on
RD undergoing primary scleral buckling or pars plana vitrectomy. We examined
the best-corrected visual acuity (BCVA) and CS before and after surgery. BCVA
and CS in the contralateral normal eyes were also measured to serve as the
normal controls. Clinical data were collected, including age, gender, surgical
procedures, number of retinal tears, circumferential dimension of retinal tears,
and area of RD.
Results: Preoperative BCVA and CS were significantly worse in eyes with RD
than in the normal eyes. CS decreased significantly after surgery, but BCVA
did not change by surgery. Postoperative CS was significantly lower in RD
eyes than in the control, but postoperative BCVA was not different between
the two eyes. Multiple regression analysis revealed that postoperative CS had
significant correlation with circumferential dimension of retinal tears, while no
clinical parameters were significantly associated with postoperative BCVA.
Conclusions: Surgery for macula-on RD did not change visual acuity, whereas
CS was significantly influenced by surgery, with which the extent of retinal tears
was associated.
PO-RET-156
Timing, Patience and Expertise: all needed in Disaster Management
Shah Mehul (1) , Shah Shreya (1) , Gupta Ashish (1) , Patel Utsav (1)
1. Drashti Netralaya
Objective: To highlight the importance of timely intervention in patient with
acute post- surgical endophthalmitis Method: One eyed patient operated for
senile immature cataract having pre-operative BCVA 6/12. SICS was done and
surgery went uneventful. On 3rd post- operative day, patient presented with
sudden diminution of vision .On examination there was lid swelling,corneal
edema hypopyon thick membrane covering PCIOL ,pupil and iris. On USG
there were vitreous opacities in ant and mid vitreous cavity.Visual acuity was
PL +ve. Immediate intravitreal antibiotics were given and decision of urgent
vitrectomy was taken according to guidelines of Endophthalmitis Vitrectomy
Study. Anterior chamber clearance was done with minimal iris handling
followed by standard 3 port pars plana vitrectomy.Surgery went uneventful
according to plan.
Result: On one month follow-up, patient is maintaining BCVA 6/9 with clear
PCIOL and normal fundus.
Conclusion: Endophthalmitis which is called nightmare for an ophthalmologist
can be managed if intervened in time with patience and expertise.
637