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Table of Contents - WOC 2012

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FP-REF-TH 35 (9)<br />

Orbscan as a Prerequsist for Laser Sub Epithelial Keratomeliuses<br />

Khan Saeed (1) , Saeed Tariq (1)<br />

1. University <strong>of</strong> Punjab<br />

Purpose: To assess the effectiveness and accuracy <strong>of</strong> orb scan in detecting<br />

hidden lesion <strong>of</strong> cornea in treating mild to moderate cases <strong>of</strong> myopia .<br />

Method: 40 patients were selected from the opd <strong>of</strong> Ch Rehmat Memorial<br />

hospital for the correction <strong>of</strong> myopia by lasek technique.<br />

Result: This retrospective study comprised <strong>of</strong> eighty eyes <strong>of</strong> 40 patients; two<br />

groups were made. Eyes belonging to group 1 with pre-operative myopia range<br />

-1.00 to -3.00 diopter with 0.75 to 1.50 diopter cylinder. In group 2 <strong>of</strong> forty eyes<br />

with pre <strong>of</strong> operative myopia range -3.00 to -6.00 diopter with -1.50 to -3.00<br />

diopter cylinder. Thirty two (80%) were female and 8 (20%) were male. Mean<br />

age <strong>of</strong> the patient was 28 years range from 20 to forty years. The orb scan was<br />

used as the mandatory tools for the assessment <strong>of</strong> corneal pathology instead<br />

<strong>of</strong> routine corneal topography. This revealed that in 3 patients had posterior<br />

keratoconous and 1 had pellucid marginal degeneration and 2 with low central<br />

corneal thickness.<br />

Conclusion: Orb scan is an effective tool in pre-operative assessment <strong>of</strong> hidden<br />

corneal defects in cases <strong>of</strong> myopia undergoing LASEK surgery.<br />

FP-REF-TH 35 (10)<br />

Crosslinking Dosage and Safety Optimization for Lasik Xtra<br />

Muller David (1) , Marshall John (1)<br />

1. Avedro<br />

Objective: Several ongoing studies point to corneal crosslinking as a viable<br />

method <strong>of</strong> reversing post-lasik ectasia. This study shows a method to<br />

incorporate crosslinking into a standard lasik procedure as a way to potentially<br />

prevent post-lasik ectasia.<br />

Purpose: To optimize dosage for corneal crosslinking used intra-operatively in<br />

the lasik surgery as a method for the prophylactic prevention <strong>of</strong> post-lasik<br />

ectasia complications (Lasik Xtra)<br />

Methods: Various strength testing methods were used in pre and post-lasik<br />

eyes and in vitro experiments at the Institute <strong>of</strong> Moorfield›s Eye Hospital in<br />

London and at Avedro, Waltham, USA<br />

Results: It was shown that only 30% <strong>of</strong> a normal cross-linking dose is required<br />

to return a post-lasik cornea back to its pre-lasik strength.<br />

Conclusions: Accelerated corneal crosslinking administered intra-operatively<br />

during the lasik procedure appears to be a promising method <strong>of</strong> returning<br />

strength to corneas weakened by lasik, possibly reducing long term instability<br />

and requiring only a minimal interruption to a normal lasik workflow.<br />

<strong>WOC</strong><strong>2012</strong> Abstract Book<br />

Free Paper: Retina - Medical<br />

Thu 16 Feb 14:30 - 16:00 Conference Room A4<br />

FP-RET-TH 36 (1)<br />

Assessment <strong>of</strong> the Safety-enhanced Protocol <strong>of</strong> Photodynamic<br />

Therapy (PDT) in the Management <strong>of</strong> Chronic and Recurrent Cases<br />

<strong>of</strong> Central Serous Chorioretinopathy (CSC)<br />

Kabeel Mamdouh (1)<br />

1. Magrabi Hospital<br />

Central Serous Chorioretinopathy (CSC) is characterized by the development<br />

<strong>of</strong> serous neurosensory retinal detachment at the posterior pole. Two groups<br />

were recruited in this study. Group I includes 10 eyes treated with the modified<br />

PDT protocol. The other group which is group II includes 8 eyes followed up<br />

for another 6 months without any interference. The safety enhanced PDT<br />

protocol using half the normal dose Verteporfin infusion, which was infused<br />

over 8 minutes followed by laser at 692 nm at 10 minutes a total light energy<br />

<strong>of</strong> 50 joules/cm2 over 83 seconds. In group I, By comparing the pre-treatment<br />

BCVA to the post-treatment BCVA, there was a significant difference, also the<br />

pre-treatment to the post treatment CFT was statistically significant difference.<br />

In group II, by comparing the pre-operative to the final follow-up BCVA, there<br />

was no statistical significant difference, also the pre-study with the final CFT<br />

at 6 months, there was also no statistical significant difference. As regards<br />

the complication following the PDT treatment, we only recorded one eye in<br />

group I that developed an area <strong>of</strong> choroidal hypoperfusion. PDT with the safety<br />

enhanced protocol for treatment <strong>of</strong> cases with chronic CSC is superior to nontreatment<br />

option.<br />

FP-RET-TH 36 (2)<br />

Two-Year Outcomes <strong>of</strong> IA-guided PDT Combined with Intravitreal<br />

Bevacizumab and Subtenon Triamcinolone Acetonide for Polypoidal<br />

Choroidal Vasculopathy<br />

Sakai Tsutomu (1) , Ohkuma Yasuhiro (1) , Hayashi Takaaki (1) , Watanabe Akira<br />

(1) (1)<br />

, Tsuneoka Hiroshi<br />

1. Jikei University School <strong>of</strong> Medicine<br />

Purpose: To evaluate the efficacy <strong>of</strong> triple therapy consisting <strong>of</strong> single-session<br />

indocyanine green angiography (IA)-guided photodynamic therapy (PDT),<br />

intravitreal bevacizumab (IVB) and subtenon triamcinolone acetonide (STTA)<br />

as initial therapy in polypoidal choroidal vasculopathy (PCV).<br />

Methods: Best corrected visual acuity and central macular thickness (CMT)<br />

were assessed at 3, 6, 12 and 24 months. Repeat injections <strong>of</strong> IVB<br />

were performed based on fluorescein angiographic findings <strong>of</strong> choroidal<br />

neovascularization leakage.<br />

Results: 15 eyes <strong>of</strong> 15 patients were analyzed. At 24 months, 70% showed<br />

gaining vision and reduction <strong>of</strong> CMT. No one had retreatment <strong>of</strong> triple therapy.<br />

IVB injections were repeated twice in five eyes.<br />

Conclusion: Initial therapy consisting <strong>of</strong> single-session PDT combined with IVB<br />

and STTA improves vision and macular morphology in PCV.<br />

53

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