Table of Contents - WOC 2012

FP-TRA-SU 269 (4)
The role of Amyloidosis in the Accelerated Ageing of the Ocular
Fundic Tissues in the Time of Age-Related Macular Degeneration
Combined with Alzheimer›s Disease
Ermilov Victor (1) , Makhonina Oksana (1)
1. Volgograd State Medical University
Objective: Amyloidosis and aging is a fundamental biological problem. The role
of amyloidosis in the mechanism of accelerated ageing of the ocular fundic
tissues combined with senile cerebral amyloidosis has not yet been investigated.
The aim of the given investigation is to study the morphological picture of the
ocular fundic tissues in cases of age-related macular degeneration (AMD)
combined with Alzheimer›s disease (AD).
Methods: There have been 188 enucleated eyes investigated, brain and other
internal organs of people who had died in homes for elderly people and in
asylums. The following methods have been used: histological, histochemical,
electron microscopic studies and selective tests for amyloid.
Results: Amyloid deposits have been found in the vessels of choroid, in the
vessels of arterial circle of Zinn-Haller, in Bruch›s membrane and sclera. A
relationship between the degree of pigment epithelium degeneration and
accumulation of amyloid in the fundus oculi was revealed.
Conclusions: The disfunctioning of the exchange in the ocular fundic tissues
plays a great role in the accelerated development of the process of ageing.
Although there is mounting and persuasive evidence of primary pathogenic
role for A? in AD, it is premature to suggest that A? plays a similar role in AMD.
FP-TRA-SU 269 (5)
Orbital Fractures: Clinical Features and Surgical Outcome
Meena Manju (1) , Medsinghe Anagha (2) , Naik Milind (2) , Honavar Santosh (2)
1. L V Prasad Eye Institute
2. L V Prasad Eye Institute
Objective: Clinical manifestations and outcome of orbital fractures repair.
Methods: Retrospective series of 98 consecutive patients.
Results: Orbital floor was fractured in 78%, diplopia was the most common
symptom (42%) and motility restriction (80%) was the most common sign.
Significant enophthalmos (>3mm) was seen in 35%. Muscle incarceration &
diplopia (29%) were indications for early surgery (