Table of Contents - WOC 2012

Free Paper: Retina - Medical
Mon 20 Feb 13:30 - 15:00 Hall 7 - Tokyo Hall
FP-RET-MO 396 (1)
Chronic Ocular Ischemia and Carotid Vascular Disease
Biseria Swarna (1) , Gupta Rachna (1) , Gupta Mohit (1)
1. L N Medical College
Aim: To detect and categorize the severity of carotid artery atherosclerosis by
performing spectral analysis of the pulsed Doppler velocity signal and B- Mode
USG in patients of ocular vascular occlusion.
Methods: Two groups of 25 each were made, patients with ocular vascular
disease as case group and those of normal as control group. All patients in
both groups were evaluated for carotid artery disease by using ultrasound
duplex scanning.
Results: Carotid artery stenosis was seen in 16 patients of case group and 8
patients of control group. Intima medial thickness was increased in 16 patients
of case group and 8 patients of control group. Duplex scanning and B mode
USG correctly detected the presence of disease in 16 of 25 carotid arteries
studied.
Conclusion: The technique is useful in individualizing the specific pattern of
occlusive changes, may be directed towards prevention of stroke or may be
indicated primarily for reversal of ocular ischemia and prevention of blindness
secondary to neovascular glaucoma.
FP-RET-MO 396 (2)
Intravitreal Injection of Bevacizumab for Treatment of Idiopathic
Choroidal Neovascularization in Chinese
Gao Lei (1) , L.V. Chunyan (2) , Liu Wenjie (3) , Lin Xuming (1) , Jiang Kai (1)
1. Antai Yuhuangding Hospital, Affiliated Hospital of Medical College
2. Haiyang Hospital of Chinese Traditional Chinese Medicine
3. Shouguang People›s Hospital
Purpose: To evaluate the safety and efficacy of intravitreal injection of
bevacizumab (IVB, 2.5mg) in Chinese patients with idiopathic choroidal
neovascularization (ICNV).
Methods: The patients treated with IVB for ICNV were reviewed. Repeated IVB
occurred if there were signs of persistent or recurrent exudation. Changes in
best corrected visual acuity (BCVA), central foveal thickness (CFT) over at
least 6 months were the main outcome measures.
Results: Forty eyes of 40 patients with the average of 33±6.8 years were
included. The mean baseline of BCVA and CFT were 0.66±0.35 and
275.39±107.59?m, respectively. One month after injection, the mean BCVA
(logMAR 0.30±0.29, P =0.000) and CFT (185.39±45.77, P =0.000) were
significantly improved. At the last visit of 9.2 months follow up, both BCVA
(logMAR 0.31±0.38, P =0.000) and CFT (192.38±55.52, P =0.000) showed
significant improvements over baseline values. A total of 52 injections were
performed in the group. About 63.6% of re-injections gained at least two lines
of vision improvement one month following the re-treatment.
Conclusion: IVB for ICNV in Chinese was well tolerated with an improvement
in BCVA, CFT over the mean 9.2 months follow-up period. Re-injection of
intravitreal bevacizumab should be administered as needed.
WOC2012 Abstract Book
FP-RET-MO 396 (3)
Primary Intravitreous Injection of Bevacizumab Combined with
Photocoagulation for Macular Edema Following Branch Retinal Vein
Occlusion
Muramatsu Daisuke (1) , Wakabayashi Yoshihiro (1) , Kimura Keisuke (1) , Agawa
Tsuyoshi (1) , Goto Hiroshi (1)
1. Tokyo Medical University
Purpose: To assess the efficacy of primary intravitreous injection of
bevacizumab (IVB) combined with photocoagulation in patients with macular
edema (ME) following branch retinal vein occlusion (BVO).
Method: Retrospective case series. Fourty nine eyes of 49 patients with
macular edema following BVO received primary IVB 1.25mg. Additional
photocoagulation and IVB was performed when Best corrected visual acuity
(BCVA; log MAR) was decreased more than 2 lines and central retinal
thickness (CRT) was increased over 20%. CRT was measured by optical
coherence tomography. The outcome was evaluated at 6, 12, 18 months after
primary IVB.
Result: Baseline BCVA and CRT were 0.54±0.32 and 536.7±142.7?m
respectively. At month 6, BCVA had improved to 0.30±0.28 (p=0.0003) and CRT
decreased to 360.7±124.9?m (p