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european college of sport science

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10:15 - 11:45<br />

Invited symposia<br />

IS-SM06 Neuromuscular Adaptation in Disuse and Ageing (JSPFSM Exchange Symposium)<br />

IS-SM06 Neuromuscular Adaptation in Disuse and Ageing (JSPFSM Exchange Symposium)<br />

RESISTANCE EXERCISE TRAINING-INDUCED MUSCLE HYPERTROPHY WAS ASSOCIATED WITH REDUCTION OF IN-<br />

FLAMMATORY MARKERS IN VERY OLD WOMEN.<br />

OGAWA, K., SANADA, K., MACHIDA, S., OKUTSU, M., SHINKAI, S., SUZUKI, K.<br />

TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY<br />

Aging is associated with low-grade inflammation, which is implicated in a variety <strong>of</strong> diseases. We investigated the effects <strong>of</strong> low-intensity<br />

resistance training on changes in physical fitness, muscle hypertrophy, and circulating growth factors and markers <strong>of</strong> inflammation in<br />

very old women. Methods: Twenty-one very old women (mean age and SD, 85.0±4.5 years) participated in 12 weeks <strong>of</strong> low-intensity<br />

resistance exercise training, which were included four types <strong>of</strong> whole body strength training once a week. Physical performance test,<br />

muscle thickness, circulating levels <strong>of</strong> C-reactive protein (CRP), serum amyloid A (SAA), heat shock protein (HSP)70, tumor necrosis factor<br />

(TNF)-α, interleukin (IL)-1, IL-6, monocyte chemotactic protein (MCP-1), insulin, insulin like growth factor (IGF)-I, and vascular endothelial<br />

growth factor (VEGF) were measured before and after the exercise training. Results: The 12 weeks <strong>of</strong> low-intensity resistance training<br />

increased abdominal (P

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