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Thursday, June 25th, 2009<br />

logical stimuli. To assess these stimuli and characterize subsequent adaptations, not only the character <strong>of</strong> exercise but also recovery<br />

should be considered when developing new training strategies.<br />

HIGH INTENSITY PHYSICAL ACTIVITY CORRELATES WITH IMPROVEMENT IN VASCULAR FUNCTION IN 9-11 YEAR OLDS.<br />

HOPKINS, N., STRATTON, G., TINKEN, T.M., MCWHANNELL, N., RIDGERS, N., GRAVES, L.E.F.<br />

LIVERPOOL JOHN MOORES UNIVERSITY<br />

Background. The prevalence <strong>of</strong> obesity and physical inactivity in Western countries has increased in recent years. Both are modifiable risk<br />

factors for cardiovascular disease. Endothelial dysfunction has its origins in childhood and plays a fundamental role in the development<br />

<strong>of</strong> the atherosclerotic disease process. However little is known about the factors which modify endothelial function in children. The present<br />

study therefore aimed to examine the relationships between change in artery health and its predictors in children.<br />

Methods This was an observational cohort study. We studied 116 nine-eleven year old children (70 female, 46 male). Flow mediated<br />

dilation (FMD), an index <strong>of</strong> vascular health, was assessed in the brachial artery and normalised for differences in its eliciting shear rate<br />

stimulus (FMD/SRAUC). Body composition was assessed by dual energy X-ray absorptiometry (DXA) and peak VO2 determined on a<br />

treadmill ergometer. Physical activity (PA) was assessed over 5 second epochs using uniaxial accelerometry across a 7 day period. All<br />

measurements were taken at baseline and repeated 16 weeks later, in order to assess whether changes in the above variables impacted<br />

upon FMD. Change scores were calculated, correlations performed and stepwise backwards linear regression used to identify<br />

predictors <strong>of</strong> change in FMD.<br />

Results No sex differences existed so data was pooled. Change in FMD/SRAUC was correlated with change in high intensity PA (r=0.3,<br />

p=0.002), change in average counts per minute (r=0.25, p=0.009) and change daily steps (p=0.202, r=0.034). Regression analysis revealed<br />

that change in high intensity PA was the only predictor <strong>of</strong> change FMD/SRAUC (r2=0.126, p=0.001).<br />

Conclusions FMD was not significantly related to changes in body composition, cardiorespiratory fitness levels or low to moderate intensity<br />

PA. The significant association between change in FMD and change in high intensity physical activity suggests that future interventions<br />

should focus on encouraging this form <strong>of</strong> behaviour.<br />

AEROBIC INTERVAL TRAINING VERSUS STRENGTH TRAINING AS A TREATMENT FOR THE METABOLIC SYNDROME<br />

STENSVOLD, D., TJØNNA, A.E., SKAUG, E.A., WISLØFF, U., SLØRDAHL, S.A.<br />

NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY<br />

Background: Physical inactivity and overweight is strongly associated with an increased risk for developing metabolic syndrome. The<br />

syndrome is characterized by a clustering <strong>of</strong> risk factors related to cardiovascular disease and mortality such as increased blood pressure,<br />

impaired glycemic control, excess <strong>of</strong> abdominal fat and dyslipidemia. Regular physical activity followed by increased fitness can<br />

improve the metabolic pr<strong>of</strong>ile and reduce the risk <strong>of</strong> developing cardiovascular diseases, however the optimal training regime for reversing<br />

metabolic syndrome and its associated cardiovascular abnormalities remain undefined.<br />

Methods: Forty subjects were randomized (stratified by gender and age) to either aerobic interval training (AIT, n=11), strength training (ST,<br />

n=10), combination <strong>of</strong> aerobic interval training and strength training (COM, n=9), or a control group (n=10). Training was performed 3<br />

times per week for 12 weeks, and risk factors comprising the metabolic syndrome were measured before and after the intervention in all<br />

four groups.<br />

Results: AIT and COM significantly increased VO2peak (34.2 ± 9.8 to 38.6 ± 11.3 ml•kg-1•min-1 for AIT and 28.4 ± 6.3 to 31.5 ± 10.2<br />

ml•kg-1•min-1 for COM). Maximal strength was significantly increased after COM (EMM 1.8 kg•lbm-0.67, 95% CI, 0.935-2.626) ST (EMM<br />

3.1 kg•lbm-0.67, 95% CI, 2.456-3.765) as well as in the control group (EMM 0.7 kg•lbm-0.67, 95% CI, -0.08-1.431). AIT significantly reduced<br />

triglyceride levels (from 2.27 ± 0.97 to 1.83 ± 0.76 mmol/l) systolic blood pressure (from 140 ± 14.6 134.2 ± 12 mmHg) and diastolic<br />

blood pressure (from 89 ± 8.1 to 85 ± 5.5 mmHg). Only ST reduced waist circumference significantly (from 111.5 ± 10.8 to 110 ± 11 cm).<br />

Endothelial function measured as flow mediated dilatation (FMD) was significantly improved in all three training groups (AIT 7.1 ± 2 to 8.8<br />

± 2.8, COM 7.2 ± 2 to 9.1 ± 2.4 and ST 8.1 ± 3.1 to 11 ± 4.7). No change occurred in weight, fasting plasma glucose, high density lipoprotein<br />

or insulin C-peptide in either group.<br />

Conclusion: Although all three training regimes improved abnormalities associated with the metabolic syndrome, 12 weeks <strong>of</strong> AIT was<br />

superior to both strength training and a combination <strong>of</strong> interval and strength training for improving risk factors related to the metabolic<br />

syndrome. Three out <strong>of</strong> the six risk factors identifying the metabolic syndrome were significantly improved after 12 weeks <strong>of</strong> aerobic<br />

interval training.<br />

EFFECTS OF DIFFERENT WARM UP INTENSITIES ON LACTATE DISTRIBUTION IN DIFFERENT BLOOD COMPARTMENTS<br />

AND POWER OUTPUT<br />

WAHL, P., ZINNER, C., HAEGELE, M., BLOCH, W., MESTER, J.<br />

GERMAN SPORT UNIVERSITY<br />

Introduction: An improved lactate tran<strong>sport</strong> across the red blood cell membrane might be an advantage during high intensity exercise by<br />

increasing the muscle-to-plasma [La] gradient and therefore allowing more lactate/H+ to leave the muscle. It is hypothised that the<br />

bioavailability <strong>of</strong> MCT (Monocarboxylattran<strong>sport</strong>er) may be altered by translocation from cytoplasm to the membrane <strong>of</strong> RBC when it is<br />

needed. Therefore we investigated if lactate tran<strong>sport</strong> across RBC membrane can functionally be influenced after maximal exercise by<br />

previous different warming up protocols (WU).<br />

Methods: At three subsequent visits to the laboratory, subjects performed 30 s lasting maximal sprint tests on a cycle ergometer with<br />

different prior warm up intensities: 1. without prior warming up (W), 2. extensive warm up (E): 12 min cycling at 60% <strong>of</strong> VO2 peak, 3. intensive<br />

warm up (I): 12 min cycling at 60% <strong>of</strong> VO2 peak including three 10 s lasting peaks at 200% <strong>of</strong> VO2 peak. After warming up, subjects<br />

stayed in a sedentary position for 5 min followed by the maximal sprint test. Blood samples were taken under resting conditions, after<br />

warming up, before sprint exercise (pre M) and in minute intervals during recovery (0 min-15 min) to determine lactate concentrations in<br />

whole blood, plasma and RBC.<br />

Results: The initial increments (pre M-0’) in plasma & RBC [La] showed significant differences between W/E and I. The RBC/plasma [La]<br />

ratio <strong>of</strong> the increments (pre M-0’) was significantly lower for I (0.23 ± 0.06) compared to W & E (W: 0.28 ± 0.04 & E: 0.27 ± 0.04). These<br />

OSLO/NORWAY, JUNE 24-27, 2009 275

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