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Friday, June 26th, 2009<br />

Discussion: As expected, strength and endurance training led to large training-specific improvements in muscle strength and aerobic<br />

performance. Combined strength and endurance training improved both neuromuscular and aerobic performance and also increased<br />

total body lean mass. Nutrition intake did not change during training. Typical Finnish diet was sufficient during high-intensity training<br />

which led to large improvements in physical fitness and to minor changes in serum basal hormones in middle-aged and older adults.<br />

RELATIONSHIP BETWEEN PHYSICAL ACTIVITY AND HEALTH IN GERMAN ADOLESCENTS – FINDINGS FROM THE KIGGS-<br />

AND THE MOMO-STUDY<br />

TITTLBACH, S., SYGUSCH, R., BREHM, W., BÖS, K.<br />

1. UNIVERSITY OF BAYREUTH, 2. UNIVERSITY OF MAINZ, 3. UNIVERSITY OF KARLSRUHE<br />

Introduction: The German Health Interview and Examination Survey for Children and Adolescents (KiGGS) is a representative, nationwide<br />

cross-sectional study on the health status <strong>of</strong> children and adolescents from ages 0 – 17. It was conducted by the Robert-Koch Institute <strong>of</strong><br />

Berlin (RKI). The KiGGS study was complemented by the Motoric-Module (MoMo) for the more differentiated recording <strong>of</strong> physical activity<br />

and physical fitness.<br />

A broad conceptualization was used in KiGGS for the assessment <strong>of</strong> health. In this understanding health is subdivided in health resources<br />

(e.g. fitness, self-esteem), risk factors and complaints (e.g. BMI, emotional problems) and a subjective over-all health measure.<br />

The analyses presented will focus on adolescents. We aim to answer the questions, (a) if there are any positive associations between<br />

physical activity and different health measures, and (b) if there are stronger associations between physical activity and health resources<br />

than between physical activity and risk factors.<br />

Methods: The common sample <strong>of</strong> the KiGGS- and the MoMo-study consists <strong>of</strong> 4,529 children and adolescents from 4-17 years <strong>of</strong> age.<br />

Subjects were randomly selected from the KiGGS-study. Focusing on the links between adolescents’ physical activity and health, a sub<br />

sample <strong>of</strong> N= 2,281 adolescents (M= 14.13, SD= 1.97; range 11-17 years <strong>of</strong> age; 50.5% boys) was used. The recording <strong>of</strong> physical activity,<br />

psychosocial health resources, physical and psychosocial complaints as well as over-all health measure was done by means <strong>of</strong> self<br />

assessment <strong>of</strong> the adolescents via questionnaire and that <strong>of</strong> the socio demographic characteristics by means <strong>of</strong> a questionnaire for<br />

parents. Physical risk factors were assessed by medical examination respectively lab findings and physical health resources by <strong>sport</strong>motor<br />

tests. Hierarchical re-gression analyses were carried out for statistical evaluation.<br />

Results: The data reveal that (highly) active adolescents have better results in most health parameters than somewhat or never physically<br />

active adolescents. Regression analyses reveal that physical activity explains up to 10% <strong>of</strong> variance in physical health resources (endurance,<br />

strength) and psychosocial health resources (self-perception <strong>of</strong> physical fitness), but is only slightly related to risk factors and complaints<br />

(e.g. BMI, cholesterol) and overall subjective health measures (e.g. wellbeing).<br />

Discussion: The results correspond to international reports, which also found only weak links between physical activity and health parameters,<br />

especially risk factors (e.g. Biddle et al., 2004). Our findings show that the relationship between physical activity and health<br />

should be conceptu-alized not only under the perspective <strong>of</strong> reducing risk factors, but rather should focus on the enhancement <strong>of</strong> physical<br />

and psychosocial resources.<br />

References<br />

Biddle SJ, Gorely T, Stensel DJ (2004). J Sports Sci 22(8), 679–701.<br />

17:15 - 18:45<br />

Invited symposia<br />

IS-BC03 The role <strong>of</strong> the inflammation process in exercised muscles<br />

INFLAMMATORY REACTIONS IN MUSCLE AFTER EXERCISE: ARE HUMANS AND ANIMALS ALIKE?<br />

PEAKE, J.<br />

QUEENSLAND ACADEMY OF SPORT<br />

Researchers have investigated inflammatory reactions to exercise-induced muscle damage in both humans and animals, using a variety<br />

<strong>of</strong> methods to induce muscle damage and assess inflammation. In humans, muscle damage is induced using downhill running, boxstepping,<br />

drop-jumps and exercise on an isokinetic dynamometer. In rats, mice and rabbits, muscle damage is induced using downhill<br />

running, electrically-stimulated lengthening muscle contractions, and local injection <strong>of</strong> cardiotoxin or snake venom. In humans, researchers<br />

have investigated alterations in leukocyte infiltration in skeletal muscle after exercise from several different perspectives, including the<br />

effects <strong>of</strong> sex, age, repeated bouts <strong>of</strong> muscle damage, exercise intensity, antioxidant supplements, and drugs (e.g., calcium channel<br />

blockers, analgesics, non-steroidal anti-inflammatory drugs). Data from these studies indicate that sex, age and repeated bouts <strong>of</strong> muscle<br />

damage influence leukocyte infiltration. Research into the relationship between leukocyte infiltration, delayed onset muscle soreness<br />

(DOMS) and changes in muscular strength is inconsistent. The effects <strong>of</strong> multiple muscle biopsies on leukocyte infiltration following exercise-induced<br />

muscle damage are also questionable. In general, animal research has produced more consistent findings concerning the<br />

effects <strong>of</strong> sex, age, oestrogen, repeated bouts <strong>of</strong> muscle damage and non-steroidal anti-inflammatory drugs. Animal models <strong>of</strong> muscle<br />

damage and inflammation provide some advantages over research involving humans. In particular, animal models allow the removal <strong>of</strong><br />

whole muscle, and more direct interventions to modulate leukocyte infiltration (e.g., gene knockout, antibodies against macrophages and<br />

neutrophils, clodronate). Comparisons between humans and animals are limited, however, for several reasons. First, fibre type distribution,<br />

oxygen delivery, oxidative potential and enzyme activity differ between human and animal muscle tissue (1). Second, the physical<br />

stress resulting from downhill running in humans likely differs from the physical stress that caged animals experience when running1.<br />

Last, electrically-stimulated contractions and injections <strong>of</strong> cardiotoxin or snake venom typically induce considerably greater muscle damage<br />

than voluntary exercise1. In summary, we can potentially learn more about muscle damage and inflammation from animal studies<br />

than we can from human studies, but caution is advised when translating animal physiology to human physiology.<br />

1. C. Malm. (2001). Acta Physiol Scand. 3: 233&#61485;239.<br />

OSLO/NORWAY, JUNE 24-27, 2009 487

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