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Encyclopedia of Evolution.pdf - Online Reading Center

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DNA comparisons between humans and Neandertals have<br />

been performed three times, with the same results (see figure<br />

on page 130). James Noonan and others working with Pääbo<br />

at the Max Planck Institute have begun an analysis <strong>of</strong> the<br />

nuclear DNA <strong>of</strong> Neandertals, and hope to complete a rough<br />

Neandertal genome by about 2008. Because nuclear DNA<br />

evolves more slowly than mtDNA, there is a much greater<br />

similarity (over 99%) <strong>of</strong> human and Neandertal nuclear<br />

DNA than <strong>of</strong> mtDNA. Geneticist Edward Rubin is pursuing<br />

similar research.<br />

Native American origins. The mitochondrial DNA <strong>of</strong><br />

tribes native to North and South America clusters into three<br />

groups. The first group is the Amerindians, which constitute<br />

most <strong>of</strong> the Native American tribes, and which may have been<br />

the first group <strong>of</strong> immigrants from Siberia into the New World<br />

after the most recent <strong>of</strong> the ice ages. The second group is the<br />

Inuit, also called Eskimos, whose ancestors arrived later, and<br />

remained in northern North America. The third group is the<br />

Na-Dene, which include the Apache and Navaho tribes. There<br />

is no clear archaeological evidence that the ancestors <strong>of</strong> the<br />

Apache and Navaho arrived in North America later than the<br />

other Native American tribes, although Navaho oral tradition<br />

indicates that when they arrived, the cliff dwellings <strong>of</strong> earlier<br />

people had already been abandoned. Their DNA reveals this<br />

important part <strong>of</strong> their history.<br />

Human linguistic diversity. Geneticist Luigi Luca Cavalli-<br />

Sforza has compared genetic variability (first <strong>of</strong> proteins, later<br />

<strong>of</strong> DNA) and patterns <strong>of</strong> linguistic diversity among human<br />

groups. The major genetic lineages <strong>of</strong> the human species correspond<br />

roughly to the major language groups in the world<br />

(see language, evolution <strong>of</strong>).<br />

Other Uses <strong>of</strong> DNA Evidence<br />

Genetic variability <strong>of</strong> endangered populations. The quantification<br />

<strong>of</strong> DNA variability is also useful to assess how much<br />

genetic variability is present in a population. Populations need<br />

genetic variability in order for natural selection to occur, and<br />

to avoid inbreeding depression. Endangered species and subspecies<br />

<strong>of</strong>ten suffer from inbreeding depression (see extinction).<br />

Also, when habitats are fragmented into small bits by<br />

human activity, such as when one big forest becomes many<br />

small woodlots surrounded by civilization, the small populations<br />

in the fragments may suffer the loss <strong>of</strong> genetic variability.<br />

DNA studies are now performed to determine the amount<br />

<strong>of</strong> genetic variability within populations <strong>of</strong> endangered species<br />

or in fragmented habitats. Without genetic variation, the<br />

evolutionary future, and therefore the future, <strong>of</strong> these populations<br />

and species is likely to be hopeless. In order to qualify<br />

for governmental protection, a population must be shown to<br />

be genetically different from other populations in order to<br />

qualify as a distinct species or subspecies.<br />

Genes and archaeology. DNA from human remains can<br />

help to identify the origins <strong>of</strong> archaeological artifacts and<br />

help reconstruct recent human prehistory. The result is a new<br />

branch <strong>of</strong> research called “bio-archaeology.” Bio-archaeology<br />

uses the analysis <strong>of</strong> DNA traces to determine what people ate,<br />

what people hunted, how they cooked, and how long ago<br />

humans domesticated various animals.<br />

DNA (raw material <strong>of</strong> evolution)<br />

Noncoding DNA, though <strong>of</strong> limited and possibly <strong>of</strong> no<br />

use to the organism, turns out to be very useful in evolutionary<br />

studies.<br />

Further <strong>Reading</strong><br />

Carroll, Sean B. The Making <strong>of</strong> the Fittest: DNA and the Ultimate<br />

Forensic Record <strong>of</strong> <strong>Evolution</strong>. New York: Norton, 2006.<br />

Cavalli-Sforza, Luigi Luca. “Genes, peoples, and languages.” Proceedings<br />

<strong>of</strong> the National Academy <strong>of</strong> Sciences USA 94 (1997):<br />

7,719–7,724.<br />

Freeman, Scott, and Jon C. Herron. “The evidence for evolution.”<br />

Chap. 2 in <strong>Evolution</strong>ary Analysis, 3rd ed. Upper Saddle River,<br />

N.J.: Pearson Prentice Hall, 2004.<br />

Friedberg, Felix, and Allen Rhoads. “Calculation and verification <strong>of</strong><br />

the ages <strong>of</strong> retroprocessed pseudogenes.” Molecular Phylogenetics<br />

and <strong>Evolution</strong> 16 (2000): 127–130.<br />

Golenberg, E. M., et al. “Chloroplast DNA sequence from a Miocene<br />

Magnolia species.” Nature 344 (1990): 656–658.<br />

Gould, Stephen Jay. “Hen’s teeth and horse’s toes.” Chap. 14 in<br />

Hen’s Teeth and Horse’s Toes: Further Reflections in Natural History.<br />

New York: Norton, 1983.<br />

Jones, Martin. The Molecule Hunt: Archaeology and the Search for<br />

Ancient DNA. New York: Arcade Publishing, 2002.<br />

Krings, Matthias, H. Geisert, Ralf Schmitz, Heike Krainitzki, Mark<br />

Stoneking, and Svante Pääbo. “DNA sequence <strong>of</strong> the mitochondrial<br />

hypervariable region II from the Neanderthal type specimen.”<br />

Proceedings <strong>of</strong> the National Academy <strong>of</strong> Sciences USA 96<br />

(1999): 5,581–5,585.<br />

———, Anne Stone, Ralf Schmitz, Heike Krainitzki, Mark Stoneking,<br />

and Svante Pääbo. “Neanderthal DNA sequences and the<br />

origin <strong>of</strong> modern humans.” Cell 90 (1997): 19–30.<br />

Lindsay, Jeff. “Does DNA evidence refute the book <strong>of</strong> Mormon?” Available<br />

online. URL: http://www.jefflindsay.com/LDSFAQ/DNA.shtml.<br />

Accessed April 18, 2006.<br />

Marks, Jonathan. What It Means to Be 98 Percent Chimpanzee:<br />

Apes, People, and Their Genes. Berkeley: University <strong>of</strong> California<br />

Press, 2002.<br />

Murphy, William J., et al. “Dynamics <strong>of</strong> mammalian chromosome<br />

evolution inferred from multispecies comparative maps.” Science<br />

309 (2005): 613–617.<br />

Noonan, James P. et al. “Sequencing and analysis <strong>of</strong> Neanderthal<br />

genomic DNA.” Science 314 (2006): 1113–1118.<br />

Pennisi, Elizabeth. “The dawn <strong>of</strong> stone age genomics.” Science 314<br />

(2006): 1068–1071.<br />

Soltis, Pamela S., Douglas E. Soltis, and C. J. Smiley. “An rbcL<br />

sequence from a Miocene Taxodium (bald cypress).” Proceedings<br />

<strong>of</strong> the National Academy <strong>of</strong> Sciences USA 89 (1992): 449–451.<br />

Wallace, Douglas C., and A. Torroni. “American Indian prehistory as<br />

written in the mitochondrial DNA: A review. Human Biology 64<br />

(1992): 403–416.<br />

Watson, James D., with Andrew Berry. DNA: The Secret <strong>of</strong> Life.<br />

New York: Knopf, 2003.<br />

Wells, Spencer. The Journey <strong>of</strong> Man: A Genetic Odyssey. Princeton,<br />

N.J.: Princeton University Press, 2003.<br />

Wilson, Allan C., and Rebecca L. Cann. “The recent African genesis<br />

<strong>of</strong> humans.” Scientific American 266 (1992): 68–73.<br />

DNA (raw material <strong>of</strong> evolution) DNA is the molecule<br />

by which information passes from one generation to the next.

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