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Encyclopedia of Evolution.pdf - Online Reading Center

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e exactly the right ones. Bovine insulin, for example, differs<br />

from human insulin by two amino acids (about a four<br />

percent difference) yet for most diabetics bovine insulin<br />

works as well as human insulin. Substitutability <strong>of</strong> different<br />

proteins has been confirmed by genetic engineering, in<br />

which the protein used by one species can substitute for the<br />

corresponding (and structurally different) protein in another<br />

species (e.g., human genes in transgenic mice). Another<br />

example is found in the evolution <strong>of</strong> the eye. Crystallins are<br />

transparent, light-refracting proteins found in the lens <strong>of</strong><br />

an eye. Animal species employ a wide variety <strong>of</strong> different<br />

protein types as crystallins. In all cases, the proteins were<br />

“co-opted” from different sources. In vertebrates, some<br />

crystallins evolved from heat shock and other stress proteins,<br />

while in insects, they evolved from proteins that are<br />

part <strong>of</strong> the external skeleton (see table). ID theory makes<br />

no allowance for the possible substitutability <strong>of</strong> different<br />

components <strong>of</strong> a supposedly “irreducibly complex” system.<br />

• Duplication and horizontal transfer <strong>of</strong> components <strong>of</strong> systems,<br />

or <strong>of</strong> entire systems. New genes can arise from the<br />

duplication and modification <strong>of</strong> old genes (see DNA [raw<br />

material <strong>of</strong> evolution]). Behe mentions this, then ignores<br />

it. Most ID theorists consider photosynthesis to be irreducibly<br />

complex. Photosynthesis <strong>of</strong> cyanobacteria, green algae,<br />

and plants has two phases. Some bacteria, however, have a<br />

simpler version <strong>of</strong> photosynthesis that closely resembles one<br />

<strong>of</strong> these systems (see photosynthesis, evolution <strong>of</strong>). It is<br />

certainly possible that cyanobacteria (the ancestors <strong>of</strong> chloroplasts;<br />

see symbiogenesis) obtained this subcomponent<br />

by horizontal gene transfer from these other bacteria.<br />

Behe admits that prokaryotic cells are simpler, and the role<br />

<strong>of</strong> symbiogenesis in the origin <strong>of</strong> eukaryotic cells, but refuses<br />

to admit this as an explanation for the supposed irreducible<br />

complexity <strong>of</strong> the eukaryotic cell. When Behe describes<br />

the complex cascade <strong>of</strong> reactions involved in the formation<br />

<strong>of</strong> a blood clot, he refers to the proteins involved without<br />

mentioning that these proteins are variant forms <strong>of</strong> serine<br />

proteases, enzymes that have functions other than blood<br />

clotting. The blood clotting genes arose as duplications <strong>of</strong><br />

serine protease genes, followed by mutations.<br />

• A creator. Behe and other ID theorists insist that you need<br />

not specify who or what created the irreducible complexity.<br />

Therefore, ID theorists insist that it is not creationism.<br />

As a result, ID theory posits a very large brick wall<br />

with a sign on it, “No scientific inquiry past this point.”<br />

This is, ultimately, what makes ID nonscientific (see scientific<br />

method). Of what kind <strong>of</strong> Creator might Behe<br />

be trying to persuade his readers? He refers to the cascade<br />

<strong>of</strong> events in blood clotting to be a Rube Goldberg apparatus,<br />

which makes it sound as if the irreducible complexities<br />

<strong>of</strong> the biological world are the product <strong>of</strong> a silly God.<br />

The Creator posited by ID also created parasites and<br />

allowed extinctions. Behe includes suffering and death as<br />

an aspect <strong>of</strong> the design <strong>of</strong> life, but he is no more successful<br />

than anyone else at explaining why a good God would<br />

have done this (see essay, “Can an <strong>Evolution</strong>ary Scientist<br />

Be Religious?”).<br />

Origins <strong>of</strong> Visual Crystallin Proteins<br />

in Different Animals (from True and Carroll)<br />

Crystallin Found in Derived from<br />

intelligent design<br />

α vertebrates small heat shock proteins<br />

β vertebrates similar to bacterial stress<br />

proteins<br />

γ vertebrates other similar to bacterial stress<br />

than birds proteins<br />

ρ frogs NADPH-dependent<br />

reductase<br />

δ turtles, lizards, arginosuccinate lyase<br />

crocodiles<br />

τ turtles, lizards α enolase<br />

π lizards glyceraldehyde phosphate<br />

dehydrogenase<br />

ε crocodiles, birds lactate dehydrogenase<br />

μ kangaroos similar to bacterial<br />

deornithine aminase<br />

η humans aldehyde dehydrogenase<br />

ζ guinea pigs, camels alcohol dehydrogenase<br />

λ rabbits hydroxyacyl-CoA<br />

deyhydrogenase<br />

L squids aldehyde dehydrogenase<br />

S octopuses glutathione S-transferase<br />

Ω octopuses aldehyde dehydrogenase<br />

O octopuses similar to yeast TSFI<br />

droso-crystallin fruit flies insect cuticle protein<br />

J1 jellyfishes similar to chaperonin heat<br />

shock protein<br />

<strong>Evolution</strong>ary scientists have been very vocal in attacking<br />

ID theory in general and Behe’s book in particular. Among<br />

the reasons are:<br />

• Behe implies that the evidence usually cited in favor <strong>of</strong> evolution<br />

does not matter (see above). It may very well be that<br />

paleontological and comparative evidence does not alter his<br />

particular argument. But by ignoring the evidence that evolution<br />

has, in fact, occurred, Behe perpetuates the misconception,<br />

prevalent in the general public, that such evidence<br />

does not exist.<br />

• Behe does use one other creationist argument that has<br />

been repeatedly discredited. He suggests that, when evolutionary<br />

scientists disagree, they must all be wrong. He<br />

cites the controversy over symbiogenesis (see Margulis,<br />

Lynn), and the controversy over punctuated equilibria<br />

(see Eldredge, Niles) to prove that all sides <strong>of</strong> these<br />

arguments must be wrong. He suggests, incorrectly, that<br />

Margulis and Eldredge have rejected natural selection. He<br />

compared the arguments <strong>of</strong> Margulis and the evolutionary<br />

biologist Thomas Cavalier-Smith, and said, “Each has<br />

pointed out the difficulties in each other’s model, and each<br />

is correct.” His conclusion is that “the natives are restless,”<br />

that is, evolutionary scientists are becoming dissatisfied

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