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Encyclopedia of Evolution.pdf - Online Reading Center

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iodiversity<br />

How Much Do Genes Control Human<br />

Behavior? (continued)<br />

suggests that the birth <strong>of</strong> older siblings influences the hormonal<br />

environment that a fetus experiences. Identical twins, separated at<br />

birth, shared the same prenatal environment.<br />

As an example <strong>of</strong> the interaction <strong>of</strong> genes and environment,<br />

Hamer cites a Swedish study <strong>of</strong> adoptions and petty crimes. The<br />

researchers assumed “bad genes” when both biological parents<br />

were criminals, and “bad home” when both adoptive parents were<br />

criminals. Here were the effects <strong>of</strong> genes and homes on the incidence<br />

<strong>of</strong> petty crimes in the youth from these homes:<br />

Good genes, good home: 3 percent petty crime rate<br />

Good genes, bad home: 7 percent petty crime rate<br />

Bad genes, good home: 12 percent petty crime rate<br />

Bad genes, bad home: 40 percent petty crime rate<br />

Good genes, good home (3 percent crime rate) was similar to<br />

population at large. The influence <strong>of</strong> genes seems to exceed that <strong>of</strong><br />

environment, but the difference between 7 percent and 12 percent<br />

may not be biologically significant. Hamer says that home environment<br />

has most <strong>of</strong> its influence on the behavior <strong>of</strong> kids, but genes<br />

have more <strong>of</strong> an effect on behavior in adulthood. Hamer therefore<br />

suggests that bad environments put kids in juvenile hall but bad<br />

genes put adults in jail.<br />

Consider these other examples <strong>of</strong> genetic influence (not<br />

genetic determination) on human behavior:<br />

Appetite. Another example that Hamer cites is obesity. Body<br />

weight is mostly an inherited trait. It takes hard work to change one’s<br />

body weight. For some people it is easy to be thin—their bodies burn<br />

the calories—while for others it is difficult to be thin, because their<br />

bodies store calories. Is there a genetic basis for appetite?<br />

Brain structure. In studies with mice, it has been found that<br />

the hunger center <strong>of</strong> the brain is in the hypothalamus. If<br />

the hunger center <strong>of</strong> the hypothalamus is removed, the<br />

mice starve even in the presence <strong>of</strong> food; and if the hunger<br />

center is stimulated, the mice overeat.<br />

Brain chemistry. A mutation that causes obesity in mice was<br />

found to influence the production <strong>of</strong> the protein leptin<br />

(“thin” in Greek). Other mutations had the same effect—it<br />

did not matter which mutation it was, so long as it influ-<br />

tropical rain forests. Two acres (a hectare) <strong>of</strong> tropical rain<br />

forest can contain as many tree or bird species as the entire<br />

United States. The rain forests, though covering less than 5<br />

percent <strong>of</strong> the Earth’s surface, may contain half <strong>of</strong> its species.<br />

The equable climatic conditions <strong>of</strong> the tropics allow them to<br />

be a museum <strong>of</strong> old species. It has so many species interactions<br />

that it is also a prime nursery <strong>of</strong> new species.<br />

Biodiversity has been repeatedly reduced by global catastrophes,<br />

most notably the five mass extinctions in Earth<br />

history. Biodiversity has increased after each mass extinction<br />

event. Sometimes it takes a long time for biodiversity to<br />

enced leptin production. Humans also have the leptin gene,<br />

and when the human version <strong>of</strong> the gene is inserted into<br />

mice, it works the same way as the mouse gene. The mutation<br />

appears to increase appetite and lower metabolism.<br />

Although humans have a leptin gene, the mutant leptin gene<br />

was found in only a few grossly obese humans. Therefore<br />

the genetic basis <strong>of</strong> human obesity must be mostly in other<br />

genes. Mutations in many different metabolic genes—in<br />

any genes that normally cause fat to burn faster—could<br />

influence appetite and cause obesity. A mutation affecting<br />

the production <strong>of</strong> a certain brain neuropeptide makes rats<br />

eat even materials that taste bad or while receiving a shock.<br />

The human counterpart might be that the brain chemical<br />

serotonin is known to be associated with anxiety, depression,<br />

and a craving for carbohydrates. Hormones influence<br />

appetites in a complex fashion: Separate hormonal mechanisms<br />

are involved in hunger for carbohydrates, for fats,<br />

and for proteins, in a manner not understood.<br />

Population variation. In twin studies, body weight had a 70<br />

percent correlation. There is also a genetic effect on<br />

type and location <strong>of</strong> body fat. A correlation was found<br />

between people with potbellies and a gene that causes<br />

blood vessels to constrict. This study was conducted in a<br />

homogeneous population <strong>of</strong> Hutterites, in order to restrict<br />

other sources <strong>of</strong> variability. Of course, environment is also<br />

important. Many people <strong>of</strong> the Pima tribe in Arizona are<br />

obese, but this is not the case with the Pima in Mexico.<br />

The two populations separated just 1,000 years ago.<br />

<strong>Evolution</strong>ary advantage. How does natural selection fit in to<br />

these considerations? In the prehistoric past, individuals<br />

who burned calories rather than saving them were less<br />

likely to survive famines, unless they compensated for it<br />

by violence. The ability to store calories, which evolutionary<br />

geneticists call the “thrifty genotype,” was beneficial<br />

in the human evolutionary past. Today, it can lead to obesity<br />

(see evolutionary medicine).<br />

Stimulation-seeking behavior. Another example <strong>of</strong> a genetic<br />

influence on behavior is the desire for stimulation. This is an important<br />

behavioral factor. People with an inclination to seek stimulation<br />

are more likely to divorce; and one <strong>of</strong> the best predictors for<br />

divorce is when one partner is inclined to seek stimulation and the<br />

other is not.<br />

recover. After the Permian extinction, more than a hundred<br />

million years was required to restore the pre-disaster<br />

diversity levels (see figure on page 48).<br />

Many scientists estimate that a sixth mass extinction,<br />

caused by human activity, is now under way. A combination<br />

<strong>of</strong> human activities is causing these extinctions. The most<br />

important is habitat destruction: Humans convert natural<br />

habitats into farmlands and cities that are unsuitable for wild<br />

species. Recovery will occur from this extinction event also.<br />

New species will eventually evolve suitable to the new, disturbed<br />

conditions created by humans. Science fiction writers

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