Dermatologic Differential Diagnosis.pdf. - Famona Site

Superficial mucocoele – oral bulla Rook p.3085, 1998,
Sixth Edition
Tape stripping bullae
VASCULAR
Chylous reflux BJD 120:695–700, 1989
Churg–Strauss disease – vesicles and bullae JAAD
47:209–216, 2002; Medicine 78:26–37, 1999
Edema – acute edema bullae of legs BJD 144:580–582, 2001
Erythema elevatum diutinum – PCT-like bullae BJD 124:89–91,
1991; perilesional vesicles and bullae Ann DV 104:75–76, 1977;
BJD 80:178–183, 1968
Erythromelalgia – edema and bullae of legs BJD 151:708–710,
2004
Henoch–Schönlein purpura Ped Derm 15:357–359, 1998; Ped
Derm 12:314–317, 1995
Lymphangioma circumscriptum BJD 83:519–527, 1970
Lymphangioma, diffuse – may or may not have widely
distributed vesicles Rook p.2283, 1998, Sixth Edition; BJD
134:1135–1137, 1996; AD 129:194–197, 1993
Lymphangiosarcoma (Stewart–Treves tumor) – bullae and
nodules in lymphedematous extremity Arch Surg 94:223–230,
1967; Cancer 1:64–81, 1948
Lymphedema, including congenital lymphedema (Milroy’s
disease); engorged dermal lymphatics mimicking appearance of
vesicles Rook p.2285, 1998, Sixth Edition
Polyarteritis nodosa – in children; fever, peripheral gangrene,
black necrosis, livedo reticularis, ulcers, nodules, vesiculobullous
lesions, arthralgia, nodules of face and extremities,
conjunctivitis JAAD 53:724–728, 2005; Ann Rheum
Dis 54:134–136, 1995
Reactive angioendotheliomatosis – red purple-purpuric patches
and plaques; includes acroangiomatosis, diffuse dermal
angiomatosis, intravascular hitiocytosis, glomeruloid
angioendotheliomatosis, angioperictomatosis (angiomatosis
with cryoproteins); associated with subacute bacterial
endocarditis, hepatitis, cholesterol emboli, arteriovenous shunt,
anti-phospholipid antibody syndrome, chronic lymphocytic
leukemia, monoclonal gammopathy, chronic renal failure,
rheumatoid arthritis JAAD 49:887–896, 2003
Stasis bullae
Temporal arteritis – bullae of scalp BJD 76:299–308, 1964
Urticarial vasculitis, including urticarial vasculitis associated with
mixed cryoglobulins, hepatitis B or C infection, IgA multiple
myeloma, infectious mononucleosis, monoclonal IgM
gammopathy (Schnitzler’s syndrome), fluoxetine ingestion,
metastatic testicular teratoma, serum sickness, Sjögren’s
syndrome, systemic lupus erythematous JAAD 38:899–905,
1998; Medicine 74:24–41, 1995; JAAD 26:441–448, 1992
Vasculitis – idiopathic, drug-induced Cutis 67:303–307, 2001;
acantholytic vesicular dermatitis with leukocytoclastic vasculitis
JAAD 15:1083–1089, 1986
Congenital Volkmann ischemic contracture (neonatal
compartment syndrome) – upper extremity circumferential
contracture from wrist to elbow; necrosis, cyanosis, edema,
eschar, bullae, purpura; irregular border with central white
ischemic tissue with formation of bullae, edema, or spotted
bluish color with necrosis, a reticulated eschar or whorled
pattern with contracture of arm; differentiate from necrotizing
fasciitis, congenital varicella, neonatal gangrene, aplasia cutis
congenital, amniotic band syndrome, subcutaneous fat
necrosis, epidermolysis bullosa BJD 150:357–363, 2004
Wegener’s granulomatosis JAAD 31:605–612, 1994
PAPULOVESICULAR DERMATITIS IN INFANTS
Absent dermatoglyphics and transient facial milia (vesicles)
JAAD 32:315–318, 1995
Behcet’s disease, neonatal
Congenital candidiasis
Congenital self-healing Langerhans cell histiocytosis JAAD
31:910–6, 1994
Eosinophilic pustular folliculitis
Erythema toxicum neonatorum
Herpes simplex infection
Infantile acropustulosis
Incontinentia pigmenti
Listeria monocytogenes infection, perinatal
Miliaria
Transient neonatal pustular melanosis
BULLAE, HEMORRHAGIC
AUTOIMMUNE DISEASES, AND DISEASES
OF IMMUNE DYSFUNCTION
Allergic contact dermatitis to poison ivy
Bullous pemphigoid Clin Exp Dermatol 13:242–243, 1988
Cicatricial pemphigoid – including hemorrhagic bullae of buccal
mucosae; adult or childhood form of cicatricial pemphigoid
Dermatitis herpetiformis JAAD 16:1274–1276, 1987
Epidermolysis bullosa acquisita, including buccal mucosa JAAD
11:820–832, 1984
Graft vs. host disease
Linear IgA disease (chronic bullous disease of childhood) –
perioral, eyelids, ears, scalp, perineum, vulva; annular polycyclic
bullae; hemorrhagic bullae Ped Derm 15:108–111, 1998;
neonatal linear IgA disease Ped Derm 10:171–176, 1993
Lupus erythematosus – systemic lupus – bullous sunburn
reaction Rook p.2472–2473, 1998, Sixth Edition; BJD
82:125–128, 1970; AD 83:910–914, 1961
Mixed connective tissue disease – with vasculitis
Morphea Cutis 44:118–119, 1989
Pemphigus vulgaris
Rheumatoid vasculitis JAAD 53:191–209, 2005; BJD
147:905–913, 2002; AD 125:1101–1104, 1989
CONGENITAL LESIONS
Aplasia cutis congenital Ped Derm 21:150–153, 2004
DRUG-INDUCED
BULLAE, HEMORRHAGIC 99
Bullous pemphigoid – penicillin, sulfasalazine, topical
5-fluorouracil, PUVA, electron beam radiotherapy Clinics
in Derm 11:515–520, 1993
Chemotherapy extravasation
Coumarin necrosis – associated with protein C deficiency
(autosomal dominant); begins 3–5 days after commencing
coumarin therapy
Fixed drug reaction
Gemcytabine extravasation
Heparin necrosis