Dermatologic Differential Diagnosis.pdf. - Famona Site

Rat bite fever
Rhizopus azygosporus BJD 153:428–430, 2005
Scorpion stings Rook p.2265, 1998, Sixth Edition
Septic emboli
Serratia marcescens JAAD 49:S193–194, 2003
Shewanella alga Clin Inf Dis 22:1036–1039, 1996
Snake bites Rook p.2265, 1998, Sixth Edition
Spider bites
Sporotrichosis BJD 148:388–401, 2003; Ghatan p.74, 2002,
Second Edition
Streptococcal ulcers of the legs – serpiginous margins with
granular base AD 104:271–280, 1971
Syphilis – secondary (malignant lues), tertiary (gumma) Rook
p.1251, 1998, Sixth Edition; tabes dorsalis – trophic ulcer Rook
p.2265, 1998, Sixth Edition; tertiary syphilis with chronic leg
ulcers Clin Dermatol 8 (3/4):157–165, 1990
Tinea corporis, pedis, Majocchi’s granuloma Rook p.2265,
1998, Sixth Edition
Tropical phagedenic ulcers – mixed infection; mixed infection
with Fusobacterium ulcerans, anaerobic cocci, Bacteroides
species, Borrelia vincenti and other organisms; papule or
bulla which breaks down to form ulcer with undermined border
BJD 148:388–401, 2003; Rook p.2266, 1998, Sixth Edition;
Int J Dermatol 27:49–53, 1988; Trans R Soc Trop Med Hyg
82:185–189, 1988; BJD 116:31–37, 1987; tropical
ulcers – anaerobic (35%) and coliform (60%) organisms
Trypanosoma brucei rhodiense J Clin Inf Dis 23:847–848, 1996
Tularemia Clin Inf Dis 20:174–175, 1995; Cutis 54:279–286,
1994
Vibrio extorquens
Vibrio vulnificus JAAD 46:S144–145, 2002
Yaws – gumma Clin Dermatol 8:157–165, 1990
Zygomycosis JAAD 30:904–908, 1994
INFILTRATIVE DISEASES
Langerhans cell histiocytosis BJD 148:388–401, 2003
INFLAMMATORY DISEASES
Crohn’s disease, metastatic – granulomatous ulcer JAAD
41:476–479, 1999; JAAD 28:115–117, 1993
Erythema multiforme BJD 148:388–401, 2003
Fibrosis from longstanding edema – ischemic ulcers Rook
p.2264, 1998, Sixth Edition
Hidradenitis suppurativa
Pancreatic panniculitis (fat necrosis)
Panniculitis, including Weber–Christian disease, lupus
profundus, α 1 -antitrypsin deficiency AD 123:1655–1661, 1987
Pyoderma gangrenosum Dermatology 195:50–51, 1997; J
Derm Surg Oncol 20:833–836, 1994; JAAD 18:559–568, 1988;
pyoderma gangrenosum with C7 deficiency JAAD 27:356–359,
1992; AD 22:655–680, 1930; bullous pyoderma gangrenosum
Sarcoid – ulcerative sarcoid – tender, ‘punched out’, and often
bilateral JAAD 53:917, 2005; AD 133:215–219, 1997; AD
123:1531–1534, 1987; AD 118:9331–933, 1982
METABOLIC
Acrodermatitis enteropathica – foot ulcers
Antiphospholipid deficiency BJD 148:388–401, 2003
ULCERS, LEG 663
Antithrombin III deficiency BJD 148:388–401, 2003
C3 deficiency BJD 148:388–401, 2003
Calcinosis – calcinosis cutis; calcinosis of muscles or
subcutaneous tissue – overlying ulceration Rook p.2267, 1998,
Sixth Edition
Calciphylaxis (vascular calcification cutaneous necrosis
syndrome) AD 140:1045–1048, 2004; BJD 143:1087–1090,
2000; JAAD 40:979–987, 1999; JAAD 33:53–58, 1995;
JAAD 33:954–962, 1995
Cold agglutinins BJD 148:388–401, 2003
Cryofibrinogenemia Am J Med 116:332–337, 2004
Cryoglobulinemia – type I NEJM 347:1412–1418, 2002; mixed –
bilateral in 87% of patients AD 139:391–393, 2003; hemorrhagic
crusted leg ulcer Cutis 70:319–323, 2002
Defective organization of the extracellular matrix of fibronectin
BJD 142:166–170, 2000
Defective fibrinolysis BJD 148:388–401, 2003
Diabetes mellitus Diabet Med 16:889–909, 1999; Diabetes
40:1305–1313, 1991; necrobiosis lipoidica diabeticorum,
ulcerative Rook p.2267, 1998, Sixth Edition; neuropathic and
large vessel and microvascular foot ulcers (mal perforans)
Factor V Leiden deficiency BJD 148:388–401, 2003; factor V
Leiden mutation and cryofibrinogenemia JAAD 51:S122–124,
2004; heterozygous factor V Leiden deficiency
BJD 143:1302–1305, 2000
Factor XIII deficiency BJD 148:388–401, 2003
Gamma heavy chain disease
Gaucher’s disease
Gout – subcutaneous tophus AD 134:499–504, 1998
Am J Pathol 32:871–895, 1956
Hematologic disease
Dysproteinemias – cryoglobulinemia, cold agglutinins,
macroglobulinemia, cryofibrinogenemia, myeloma, polyclonal
dysproteinemia BJD 148:388–401, 2003
Red blood cell disorders – sickle cell disease, hereditary
spherocytosis Ped Derm 20:427–428, 2003; Clin Exp
Dermatol 16:28–30, 1991; in atypical locations (backs of feet)
Dermatologica 181:56–59, 1990; thalassemia, polycythemia
vera, G-6PD deficiency, hereditary elliptocytosis, hereditary
non-spherocytichemolytic anemia BJD 148:388–401, 2003
White blood cell disease – leukemia, granulocytopenia BJD
148:388–401, 2003
Platelet disorders – essential thrombocythemia
Hautarzt 35:259–262, 1984; Br J Surg 60 (5):377–380,
1973; thrombotic thrombocytopenic purpura BJD
148:388–401, 2003
Felty’s syndrome BJD 148:388–401, 2003; Ghatan p.74,
2002, Second Edition
Thrombotic angiopathy
Edema due to cardiac or renal failure
Extramedullary hematopoiesis JAAD 4:592–596, 1981
Gamma heavy chain disease
Gout BJD 148:388–401, 2003
Homocysteinemia Ned Tijdschr Geneeskd 142:2706–2707,
1998 (Dutch)
Hyperoxaluria – livedo reticularis, ulcers, and peripheral
gangrene JAAD 49:725–728, 2003; AD 136:1272–1274, 2000
Hyperparathyroidism BJD 83:263–268, 1970
Hyperviscosity – paraproteinemia, leukemia BJD 148:388–401,
2003
Malnutrition
Myxedema BJD 148:388–401, 2003
Necrobiosis lipoidica diabeticorum JAAD 17:351–354, 1987