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Dermatologic Differential Diagnosis.pdf. - Famona Site

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702 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1<br />

Ghatan p.79, 2002, Second Edition; Terry’s nails (proximal<br />

80% of nail plate is white, distal 20% is pink) Ghatan p.85,<br />

2002, Second Edition<br />

Hypopituitarism – diffuse loss of pigment Rook p.1807, 1998,<br />

Sixth Edition<br />

Iron deficiency – hypopigmented hair Ghatan p.69, 2002,<br />

Second Edition<br />

Kwashiorkor – hypochromotrichia and hypopigmentation of skin<br />

Cutis 67:321–327, 2001; Cutis 51:445–446, 1993<br />

Liver disease – leukonychia Ghatan p.79, 2002, Second Edition;<br />

white lunulae Ghatan p.80, 2002, Second Edition; Terry’s nails<br />

Ghatan p.85, 2002, Second Edition<br />

Malabsorption – AIDS, inflammatory bowel disease, vitamin<br />

B12 deficiency; hypopigmented hair Ghatan p.69, 2002, Second<br />

Edition; white lunulae Ghatan p.80, 2002, Second Edition<br />

Necrobiosis lipoidica diabeticorum – of scalp with central<br />

depigmentation Trans St John’s Hosp Dermatol Soc<br />

57:202–220, 1971<br />

Oast-house disease – white hair, recurrent edema; increased<br />

serum methionine Rook p.2965, 1998, Sixth Edition<br />

Panhypopituitarism – pale, yellow tinged skin Ghatan p.165,<br />

2002, Second Edition<br />

Pellagra – leukonychia Ghatan p.79, 2002, Second Edition<br />

Pernicious anemia – vitiligo, canities Rook p.1783, 1998,<br />

Sixth Edition<br />

Phenylketonuria – phenylalanine hydroxylase deficiency; fair<br />

skin and hair Rook p.2645,2965, 1998, Sixth Edition; lichen<br />

sclerosus-like changes JAAD 49:S190–192, 2003<br />

Prolidase deficiency – autosomal recessive; atrophie blanche<br />

lesions; skin spongy and fragile with annular pitting and<br />

scarring; leg ulcers; photosensitivity, telangiectasia, purpura,<br />

premature graying, lymphedema Ped Derm 13:58–60, 1996;<br />

JAAD 29:819–821, 1993; AD 127:124–125, 1991; AD<br />

123:493–497, 1987<br />

Renal disease – hypopigmented hair Ghatan p.70, 2002,<br />

Second Edition; transverse white nail bands Ghatan p.81,<br />

2002, Second Edition; half and half nails (Lindsay’s nails)<br />

Textbook of Neonatal Dermatology, p.512, 2001; generalized<br />

pallor<br />

Thyroid disease Rook p.1807, 1998, Sixth Edition; white lunulae<br />

Ghatan p.80, 2002, Second Edition; hyper- or hypothyroidism –<br />

vitiligo Ghatan p.166, 2002, Second Edition<br />

Vitamin B12 deficiency – white hair AD 122:896–904, 1986<br />

Zinc deficiency – leukonychia Ghatan p.79, 2002, Second<br />

Edition; Muehrcke’s paired lines Textbook of Neonatal<br />

Dermatology, p.512, 2001<br />

NEOPLASTIC DISEASES<br />

Basal cell carcinoma – with depigmented halo Ghatan p.251,<br />

2002, Second Edition<br />

Blue nevus – with depigmented halo Ghatan p.251, 2002,<br />

Second Edition<br />

Clear cell papulosis – white macules on the lower abdomen<br />

in infancy with later development of these lesions in the milk<br />

line BJD 138:678–683, 1998; Am J Surg Pathol 11:827–834,<br />

1987<br />

Dermatofibroma – with depigmented halo Ghatan p.251, 2002,<br />

Second Edition<br />

Extramammary Paget’s disease – white patches of vulva<br />

BJD 151:1049–1053, 2004<br />

Histiocytosis, malignant – multiple erythematous plaques with<br />

depigmentation Am J Dermatopathol 19:299–302, 1997<br />

Lymphoma – hypopigmented cutaneous T-cell lymphoma<br />

J Dermatol 27:543–546, 2000; AD 128:1265–1270, 1992;<br />

depigmented macules of erythrodermic CTCL JAAD<br />

46:325–357, 2002; in childhood Ped Derm 14:449–452, 1997;<br />

AD 130:476–480, 1994; JAAD 17:563–570, 1987<br />

Macroglobulinemia<br />

Melanocytic nevus, congenital or acquired – halo nevus Ghatan<br />

p.251, 2002, Second Edition; atypical nevi, non-pigmented<br />

AD 113:992–994, 1997<br />

Halo nevus (Sutton’s nevus; leukoderma acquisitum<br />

centrifugum) – depigmented skin and hair AD 92:14–35, 1965<br />

Halo nevus without nevus<br />

Melanoma – leukoderma; hypopigmented hair; regressed<br />

melanoma – white scar JAAD 53:101–107, 2005<br />

Neurofibroma – with halo Ghatan p.251, 2002, Second Edition<br />

Nevus depigmentosus Textbook of Neonatal Dermatology,<br />

p.361–362, 2001<br />

Seborrheic keratosis – with halo Ghatan p.251, 2002,<br />

Second Edition<br />

Tumor of the follicular infundibulum<br />

White sponge nevus<br />

PARANEOPLASTIC DISORDERS<br />

Carcinoid syndrome – white macules surrounded by erythema<br />

and telangiectasia BJD 90:547–551, 1974<br />

Tripe palms<br />

PHOTODERMATOSES<br />

Chronic actinic dermatitis with vitiligo-like depigmentation Clin<br />

Exp Dermatol 17:38–43, 1992<br />

PRIMARY CUTANEOUS DISEASES<br />

Albinism – tyrosinase negative (type IA), yellow mutant (type<br />

IB), platinum, tyrosinase positive (type II), minimal pigment,<br />

brown, rufous, Hermansky–Pudlak syndrome – hypopigmented<br />

skin and hair JAAD 19:217–255, 1988<br />

Albinoidism JAAD 19:217–255, 1988<br />

Alopecia areata – white (hair) overnight AD 102:162–167, 1970;<br />

white lunulae Ghatan p.80, 2002, Second Edition<br />

Atopic dermatitis – white dermatographism Rook p.2128, 1998,<br />

Sixth Edition; pallor around mouth, nose, and ears Ghatan<br />

p.125, 2002, Second Edition; post-inflammatory depigmentation<br />

in dark skinned patients secondary to rubbing and<br />

lichenification<br />

Atrophoderma of Pasini and Pierini<br />

Balanitis xerotica obliterans<br />

Bier’s spots<br />

Canities – white hair<br />

DIFFUSE HYPOMELANOSIS OF SCALP HAIR<br />

Book syndrome<br />

Chediak–Higashi syndrome<br />

Chronic protein loss or deficiency (kwashiorkor, renal disease,<br />

inflammatory bowel disease, malabsorption)<br />

Down’s syndrome<br />

Elejalde’s syndrome<br />

Fanconi syndrome

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