Dermatologic Differential Diagnosis.pdf. - Famona Site

116 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Elephantiasis nostras of the lips – presumed streptococcal
infection Oral Surg Oral Med Oral Pathol Endod 84:297–300,
1997
Hand, foot and mouth disease (Coxsackie virus) Rook
p.3133–3134, 1998, Sixth Edition
Herpes simplex – primary, recurrent, eczema herpeticum
Rook p.3133–3134, 1998, Sixth Edition
Herpes zoster Rook p.3133–3134, 1998, Sixth Edition
Impetigo – streptococcal or staphylococcal Rook p.3133–3134,
1998, Sixth Edition
Leishmania brasiliensis J Clin Inf Dis 22:1–13, 1996
Measles – red granular lips Tyring p.408, 2002
Orf Br Dent J 173:343–344, 1992
Parvovirus B19, including papular–purpuric ‘gloves and socks’
syndrome – swollen lips with painful erosive cheilitis JAAD
41:793–796, 1999
Scarlet fever
Scopulariopsis brevicaulis – ulcerous granulomatous cheilitis
JAAD 31:881, 1994
Staphylococcus aureus – angular cheilitis Rook p.1068, 1998,
Sixth Edition; fissuring of midline of lower lip Clin Exp Dermatol
11:289–291, 1986
Syphilis – primary chancre; secondary – split papules (angular
cheilitis) Rook p.1247, 1998, Sixth Edition; congenital syphilis –
split papules Rook p.1254, 1998, Sixth Edition
Trichophyton rubrum Oral Surg Oral Med Oral Pathol
30:201–206, 1970
Vaccinia Br Dent J 143:57–59, 1977
Varicella
Yaws
INFILTRATIVE
Plasma cell cheilitis – with lip ulcer JAAD 30:789–780, 1994
INFLAMMATORY DISEASES
Cheilitis granulomatosa (Miescher’s cheilitis) Oral Dis
3:188–192, 1997; AD 124:1706–1709, 1988; J Oral Maxillofac
Surg 44:474–478, 1986; Dermatologica 91:57–64, 1945
Crohn’s disease – granulomatous cheilitis, fissures of lips, and
angular cheilitis with ulceration; multiple aphthae, cobblestoning
of the buccal mucosa, linear ulcers of the sulci, pyostomatitis
vegetans, fissures of the lower lip, tiny nodules of the gingival
and alveolar mucosa J Pediatr Gastroenterol Nutr
32:339–341,2001; AD 135:439–442, 1999; JAAD 36:986–988,
1997; J R Soc Med 75:414–417, 1982; JAAD 5:689–695, 1981;
angular cheilitis Rook p.3120, 1998, Sixth Edition
Erythema multiforme – hemorrhagic cheilitis of
Stevens–Johnson syndrome Rook p.3133, 1998, Sixth Edition
Orofacial granulomatosis Br Dent J 163:154–157, 1987
Periadenitis mucosae necrotica recurrens (Sutton’s disease)
AD 133:1161–1166, 1997
Pyostomatitis vegetans Rook p.3142, 1998, Sixth Edition
Sarcoid – granulomatous cheilitis JAAD 29:822–824, 1993
Toxic epidermal necrolysis Rook p.2086, 1998, Sixth Edition;
BJD 68:355–361, 1956
METABOLIC
Acrodermatitis enteropathica (zinc deficiency) – angular cheilitis
Ped Derm 19:426–431, 2002; Rook p.2670, 1998, Sixth Edition;
acquired zinc deficiency with erythema and scaling of entire
vermilion
Ariboflavinosis – angular stomatitis
Celiac disease – angular cheilitis Rook p.3120, 1998,
Sixth Edition
Folic acid – angular cheilitis Lancet Aug 28;2 (7722):453–454,
1971
Hartnup’s disease – cheilitis and angular stomatitis
Iron deficiency – angular cheilitis J Am Dent Assoc 99:640–641,
1979
Kwashiorkor (protein and caloric deprivation) – angular cheilitis
and cheilitis Cutis 67:321–327, 2001; JAAD 21:1–30, 1989
Liver disease, chronic (cirrhosis) – cheilitis; zinc deficiency;
generalized dermatitis of erythema craquele (crackled and
reticulated dermatitis) with perianal and perigenital erosions
and crusts, hair loss Rook p.2726, 1998, Sixth Edition;
Ann DV 114:39–53, 1987
Malabsorption – angular cheilitis Rook p.3120, 1998,
Sixth Edition
Methylmalonic acidemia, cobalamin C type – red lips Dermatol
Pediatr Lat 1:46–48, 2003; AD 133:1563–1566, 1997
Pellagra (niacin deficiency) – crusted lips; Casal’s necklace; red
pigmented sharply marginated photodistributed rash, including
drug-induced pellagra-like dermatitis – 6-mercaptopurine,
5-fluorouracil, INH (all of the above – also seb derm-like);
resembles Hartnup disease Cutis 68:31–34, 2001; Ped Derm
16:95–102, 1999; BJD 125:71–72, 1991
Pernicious anemia – angular cheilitis Rook p.3120, 1998,
Sixth Edition
Porphyria cutanea tarda – cheilitis of lower lip Oral Surg Oral
Med Oral Pathol Oral Radiol Endod 90:705–708, 2000; angular
cheilitis
Pseudoglucagonoma syndrome due to malnutrition – angular
cheilitis AD 141:914–916, 2005
Vitamin B2 (riboflavin) deficiency – angular cheilitis; sore red
lips, tongue, and mouth Clinics in Derm 17:457–461, 1999;
AD 112:70–72, 1976
NEOPLASTIC DISEASES
Actinic cheilitis Oral Surg Oral Med Oral Pathol Oral Radiol
Endod 88:181–186, 1999; Rook p.1676, 1998, Sixth Edition;
Derm Surg 23:15–21, 1997
Basal cell carcinoma
Benign lymphoplasia – pruritic cheilitis; itching of the vermilion
border Oral Surg Oral Med Oral Pathol 55:759–767, 1983;
Oral Surg Oral Med Oral Pathol 55:359–362, 1983
Hyperkeratotic cheilitis in association with proliferative
verrucous leukoplakia JAAD 41:481–483, 1999
Leukoplakia
Leukemic macrocheilitis JAAD 14:353–358, 1986
Squamous cell carcinoma
PARANEOPLASTIC DISEASES
Glucagonoma syndrome (necrolytic migratory erythema) –
angular cheilitis; scaling papules and plaques JAAD
24:473–477, 1991
Paraneoplastic pemphigus – erosive cheilitis; associated with
Castleman’s disease, non-Hodgkin’s lymphoma, thymoma, or
follicular dendritic cell sarcoma BJD 153:558–564, 2005;
Hautarzt 52:159–172, 2001; NEJM 323:1729–1735, 1990