Dermatologic Differential Diagnosis.pdf. - Famona Site

Tricho-odonto-onycho-ectodermal dysplasia (linear dermal
hypoplasia) – hypotrichosis, hypodontia, focal linear dermal
hypoplasia of the tip of the nose, irregular hyperpigmentation
of the back, bilateral amastia and athelia, nerve hearing loss
AD 122:1047–1053, 1986
Trichothiodystrophy syndromes – BIDS, IBIDS, PIBIDS – facial
hemiatrophy, lipoatrophy, sparse or absent eyelashes and
eyebrows, brittle hair, premature aging, sexual immaturity,
ichthyosis, dysmyelination, bird-like facies, dental caries;
trichothiodystrophy with ichthyosis, urologic malformations,
hypercalciuria and mental and physical retardation Ped Derm
14:441–445, 1997; JAAD 44:891–920, 2001
Trisomy D (13–15) – membranous aplasia cutis,
holoprosencephaly, seizures, ocular abnormalities,
deafness, neural tube defects Textbook of Neonatal
Dermatology, p.127, 2001
Trisomy 13/18 – scalp defects BJD 151:953–960, 2004; thin
or atrophic nails Ghatan p.109, 2002, Second Edition
Tuberous sclerosis – hypoplasia of the hand BJD 135:1–5, 1996
Turner’s syndrome – thinning and wrinkling of palmar skin; thin
or atrophic nails Ghatan p.109, 2002, Second Edition
Twenty nail syndrome – atrophic nails Ghatan p.114, 2002,
Second Edition
Unusual facies, lipodystrophy, joint contractures (Werner-like
disorder) Hum Genet 83:209–216, 1989
Van der Woude syndrome – congenital lower lip pits
Vertebral and eye anomalies, cutis aplasia, and short stature
(VECS) Am J Med Genet 77:225–227, 1998
Werner’s syndrome – loss of subcutaneous tissue; bird-like
facies, spindly legs Am J Med 108:143–152, 2000; AD
124:90–101, 1988
Wiedemann–Rautenstrauch (neonatal progeroid syndrome) –
generalized lipoatrophy, macrocephaly, premature aging,
wide open sutures, hypoplasia of facial bones, low-set ears,
beak shaped nose, neonatal teeth, slender limbs, large
hands and feet with long fingers, large penis J Med Genet
34:433–437, 1997
Williams syndrome – premature laxity of skin, congenital heart
disease (supravalvular aortic stenosis), baggy eyes, full cheeks,
prominent lips, dental malocclusion, delayed motor skills,
cocktail party personality J Pediatr 113:318–326, 1988
Wolf–Hirschhorn syndrome (del (4p) syndrome) – midline scalp
defect BJD 151:953–960, 2004; Am J Med Genet 21:351–358,
1985
Wrinkly skin syndrome – wrinkled skin on abdomen and dorsal
aspects of hands and feet, increase palmoplantar creases,
prominent venous pattern on chest, mental retardation,
microcephaly, hypotonia, musculoskeletal abnormalities Am J
Med Genet 101:213–220, 2001; Ped Derm 16:113–117, 1999
X-p22 microdeletion syndrome – bilateral reticulated and linear
defects of malar region of face, microphthalmia, sclerocornea
Textbook of Neonatal Dermatology, p.127, 2001
Xeroderma pigmentosum Ghatan p.5, 2002, Second Edition
TRAUMA
Acupuncture – atrophic round scars BJD 150:364, 2004
Amniocentesis dimples Am J Obstet Gynecol 126:247–252,
1976; JAAD 39:888–890, 1998; AD 120:1360–1362, 1984
Compression from tight fitting clothes – lipoatrophy JAAD
45:325–361, 2001
IVDA – skin popping BJD 150:1–10, 2004
Injury due to obstetric forceps or scalp electrodes
Physical trauma – atrophic nails Ghatan p.114, 2002,
Second Edition
Post-injection lipoatrophy JAAD 45:325–361, 2001
Radiation dermatitis, chronic
Scars
VASCULAR
BASAL CELL CARCINOMA – SYNDROMES 73
Acrocyanosis with atrophy AD 124:263–268, 1988
Atherosclerosis and other vascular disorders – atrophic nails
Ghatan p.114, 2002, Second Edition
Atrophie blanche (livedo with ulceration) – ivory white plaque
of sclerosis with stippled telangiectasias and surrounding
hyperpigmentation; venous insufficiency, thalassemia minor
Acta DV (Stockh) 50:125–128, 1970; cryoglobulinemia,
systemic lupus erythematosus, scleroderma Rook p.2216,2249,
1998, Sixth Edition; Arch Pathol Lab Med 110:517–519, 1986;
JAAD 8:792–798, 1983; AD 119:963–969, 1983
Cutis marmorata telangiectatica congenita – facial or limb
hypoplasia JAAD 48:950–954, 2003; Ped Derm 17:100–104,
2000; JAAD 20:1098–1104, 1989
Degos’ disease (malignant atrophic papulosis) – white atrophic
papules BJD 139:708–712, 1998; AD 128:255–260, 1992; lower
extremity hypoplasia Turk J Pediatr 43:159–161, 2001
Edema – acute leg edema; stria-like distension of skin AD
138:641–642, 2002
Glomerulovenous malformation – atrophic patch with redundant
skin Soc Ped Derm Annual Meeting, July 2005
Hemangiomas, resolved – atrophy, telangiectasia, redundant
skin Rook p.554, 1998, Sixth Edition
Rapidly involuting congenital hemangioma (RICH) – residual
patch of thing skin with prominent veins after involution JAAD
50:875–882, 2004
Raynaud’s phenomenon – atrophic nails Ghatan p.114, 2002,
Second Edition
Servelle–Martorell syndrome – association of capillary stains
and dysplastic veins with undergrowth of affected limb Curr
Prob Dermatol 13:249–300, 2002; Textbook of Neonatal
Dermatology, p.333, 2001
Takayasu’s arteritis – post-granulomatous anetoderma AD
123:796–800, 1987
Varicose veins – acquired localized elastolysis Clin Exp
Dermatol 20:492–495, 1995
BASAL CELL CARCINOMA –
SYNDROMES
Bazex–Dupré–Christol syndrome (X-linked dominant) – milia
and comedo-like papules, hypotrichosis, anhidrosis of face and
head, follicular (vermiculate) atrophoderma of the face, elbows
and hands; basal cell carcinomas resemble nevi; multiple
follicular hamartomas with sweat gland and sebaceous
differentiation Derm Surg 26:152–154, 2000; Ped Derm
16:108–110, 1999; JAAD 39:853–857, 1998; AD 130:337–342,
1994; Ann Dermatol Syphilgr (Paris) 93:241–254, 1966
Coarse sparse hair and milia syndrome JAAD 50:489–494, 2004
Multiple hereditary non-syndromic basal cell carcinomas JAAD
50:489–494, 2004
Nevoid basal cell carcinoma syndrome (Gorlin’s syndrome) –
autosomal dominant; papules of the face, neck, and trunk,
calcifications of the brain, palmoplantar pits, mandibular
keratocysts, skeletal anomalies, basal cell carcinomas; also