Dermatologic Differential Diagnosis.pdf. - Famona Site

274 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Rubinstein–Taybi syndrome (broad thumb hallux syndrome) –
chromosome 16p; mutation in gene encoding cyclic adenosine
monophosphate response element-binding protein Nature
376:348–351, 1995; mental deficiency, small head, broad thumbs
and great toes, beaked nose, malformed low-set ears, capillary
nevus of forehead, hypertrichosis of back, shoulders, and
eyebrows, synophrys, keloids, cardiac defects JAAD 48:161–179,
2003; JAAD 46:161–183, 2002; JAAD 37:295–297, 1997; Cutis
57:346–348, 1996; Am J Dis Child 105:588–608, 1963; hirsutism
of shoulders and back Am J Med Genet Suppl 6:17–29, 1990
Rudimentary meningocoele and membranous aplasia cutis
AD 131:1427–31, 1995
Sequestrated meningocoele – either tuft of hair or annular array
of hair Ped Derm 14:315–318, 1994
Schinzel–Gideon syndrome – localized hypertrichosis of face
and digits JAAD 48:161–179, 2003
Scrotal hair Textbook of Neonatal Dermatology, p.498, 2001
Setleis syndrome (focal facial dermal dysplasia) – autosomal
recessive; aged leonine appearance, bi-temporal scar-like
defects, absent or multiple rows of upper eyelashes, eyebrows
slanted up and out, scar-like median furrow of chin Ped Derm
21:82–83, 2004; BJD 130:645–649, 1994; Pediatrics
32:540–548, 1963
Stiff skin syndrome – hypertrichosis of eyebrows
JAAD 48:161–179, 2003; Dermatology 190:148–151, 1995
Striated muscle hamartoma AD 136:1263–1268, 2000;
Ped Derm 3:153–157, 1986
Supernumerary nipple (polythelia pilosa) – supernumerary
nipple without the nipple Cutis 71:344–346, 2003
Tented eyebrows JAAD 37:295–297, 1997
Thoracic hypertrichosis
Treacher Collins syndrome (mandibulofacial dysostosis) –
partial or total alopecia of lower eyelashes, scarring alopecia,
characteristic facies, malformed pinnae, extension of scalp
hair onto cheeks; blind fistulae between ear and angle of mouth
Am J Dis Child 113:405–410, 1967
Tricho-rhino-phalangeal syndrome (Langer–Giedion syndrome) –
broad eyebrows
Waardenburg’s syndrome – synophrys; widow’s peak
JAAD 37–295–297, 1997
Widow’s peak, ptosis, and skeletal abnormalities Am J Med
Genet 33:357–363, 1989
Winchester syndrome – hypertrichosis of shoulders and arms,
joint contractures, corneal opacities, systemic hyalinosis
JAAD 48:161–179, 2003
DEGENERATIVE DISEASES
Peripheral neuropathy; anterior cervical hypertrichosis
associated with motor and sensory neuropathy JAAD
25:767–770, 1991
DRUGS
Drug-induced – face, trunk, hands Clinics in Dermatol
11:99–106, 1993
Accutane – 13-cis-retinoic acid
Acetazolamide – hirsutism Am J Ophthalmol 78:327–328, 1974
ACTH Ghatan p.68, 2002, Second Edition
Anabolic steroids – hirsutism Ghatan p.68, 2002,
Second Edition; Cutis 44:30–35, 1989
Benoxaprofen – face and extremities Br Med J
248:1228–1229, 1982
Corticosteroids, topical Ped Derm 18:57–59, 2001
Cyclosporine Dermatologica 172:24–31, 1986
Danazol – facial hirsutism Cutis 74:301–303, 2004
Diazoxide – hirsutism Ann NY Acad Sci 150:373, 1982
Dilantin JAAD 18:721–741, 1988
Interferon NEJM 311:1259, 1984; eyelashes J Interferon
Cytokine Res 20:633–634, 2000
Iodine JAAD 48:161–179, 2003
Latanoprost – topical – eyelash hypertrichosis Cutis
67:109–110, 2001
Methoxsalen
Minoxidil BJD 101:593–595, 1979
Penicillin
Penicillamine
Progesterone
Prostaglandin F 2α analog (latanoprost) eyedrops –
trichomegaly (eyelash hypertrichosis) JAAD 44:721–723,
2001; Cutis 67:109–110, 2001
PUVA Ped Derm 18:57–59, 2001
Spironolactone
Streptomycin Ann Paediatr 174:389–392, 1950
Tacrolimus, topical Ped Derm 22:86–87, 2005
Testosterone, topical or systemic – hirsutism Ghatan p.68,
2002, Second Edition
EXOGENOUS AGENTS
Cast application Ped Derm 18:57–59, 2001
Chloracne Dermatol Clin 12:569–576, 1994
Skin graft
INFECTIONS OR INFESTATIONS
AIDS – trichomegaly of eyelashes J Eur Acad Dermatol
Venereol 11:89–91, 1998; Arch Ophthalmol 115:557–558,
1997; JAAD 25:801–804, 1991; hairy pinnae JAAD
28:513, 1993
Leishmaniasis – kala-azar – Pitaluga’s sign – trichomegaly
Post-encephalitis Ghatan p.69, 2002, Second Edition
Vaccination sites JAAD 48:161–179, 2003
Varicella – transient circumscribed hypertrichosis Pediatrics
50:487–488, 1972
INFILTRATIVE LESIONS
Lichen amyloidosis
INFLAMMATORY DISORDERS
Inflammation – hypertrichosis overlying any site of chronic
inflammation or friction (napsack, chewing Arch Dermatol
Syphilol 65:458–460, 1952; vaccination – hairy scar following
smallpox vaccination Indian J Pediatr 35:283–284, 1968; after
measles vaccine Ped Derm 18:457–458, 2001; BCG,
diphtheria; overlying wound, surgical excision, chronic venous
insufficiency Postgrad Med 43:545–546, 1967; around burn
Br J Plast Surg 32:93–95, 1979; excoriated insect bites
AD 117:129–131, 1981; gonococcal arthritis, overlying
osteomyelitis, with dermatitis, following varicella Paediatrics
50:487–488, 1972; linear overlying thrombophlebitis
AD 124:30–31, 1988; Rook p.2894, 1998, Sixth Edition;
insect bites Ped Derm 18:57–59, 2001; following radical
lymphadenectomy Ped Derm 18:57–59, 2001; overlying arthritis
Stevens–Johnson syndrome – acquired distichiasis Rook
p.2994, 1998, Sixth Edition; Am J Med Genet 65:109–112, 1996