Dermatologic Differential Diagnosis.pdf. - Famona Site

Robert’s syndrome (hypomelia–hypotrichosis–facial
hemangioma syndrome) – autosomal recessive; mid-facial port
wine stain extending from forehead to nose and philtrum, cleft
lip with or without cleft palate, sparse silver-blond hair, limb
reduction malformation, characteristic facies, malformed ears
with hypoplastic lobules, marked growth retardation Clin Genet
31:170–177, 1987; Clin Genet 5:1–16, 1974
Rombo syndrome – perioral cyanotic erythema
Rothmund–Thompson syndrome JAAD 27:750–762, 1992
Rubinstein–Taybi syndrome – port wine stain of forehead Rook
p.581, 1998, Sixth Edition
Sturge–Weber syndrome (encephalofacial angiomatosis) –
facial port wine stain with homolateral leptomeningeal
angiomatosis Pediatrics 76:48–51, 1985
Sweet’s syndrome
Trisomy 13 – ACC of scalp with holoprosencephaly, eye
anomalies, cleft lip and/or palate, polydactyly, port wine stain
of forehead Rook p.581, 1998, Sixth Edition; J Med Genet
5:227–252, 1968; Am J Dis Child 112:502–517, 1966
Thrombocytopenia–absent radii (TAR) syndrome – congenital
thrombocytopenia, bilateral absent or hypoplastic radii, port
wine stain of head and neck AD 126:1520–1521, 1990;
Am J Pediatr Hematol Oncol 10:51–64, 1988
Wyburn–Mason (Bonnet–Duchaume–Blanc) syndrome –
unilateral salmon patch with punctate telangiectasias or port
wine stain; unilateral retinal arteriovenous malformation,
ipsilateral aneurysmal arteriovenous malformation of the brain
Am J Ophthalmol 75:224–291, 1973
Xeroderma pigmentosum
TOXINS
Acrodynia (pink disease) – mercury poisoning; red cheeks and
nose Ped Derm 21:254–259, 2004; AD 124:107–109, 1988
Dioxin exposure – JAAD 19:812–819, 1988
Mustard gas exposure – sunburn-like erythema JAAD
19:529–536, 1988
Scombroid fish poisoning
Self-defense sprays Ann DV 114:1211–1216, 1987
TRAUMA
Airbag dermatitis – bizarre shapes of erythema, resembling
factitial dermatitis JAAD 33:824–825, 1995
Burns – thermal, ultraviolet, X-ray, laser
Changes in temperature
Cold panniculitis in children Burns Incl Therm Inj 14:51–52,
1988
Dermabrasion
Erythema ab igne
Frostbite
Neonatal cold injury – facial erythema or cyanosis; firm pitting
edema of extremities spreads centrally; skin is cold; mortality
of 25% Rook p.482, 1998, Sixth Edition; Br Med J 1:303–309,
1960
Physical trauma
Popsicle panniculitis
Sunburn
VASCULAR DISEASES
Angiosarcoma of the face – resembles rosacea JAAD
38:837–840, 1998
Cutis marmorata telangiectatica congenita – hyperemic face
BJD 137:119–122, 1997; JAAD 20:1098–1104, 1989;
AD 118:895–899, 1982; Am J Dis Child 112:72–75, 1966
Port wine stain
Salmon patch (nevus simplex) (‘stork bite’) – pink macules with
fine telangiectasias of the nape of the neck, glabella, forehead
upper eyelids, tip of nose, upper lip, midline lumbosacral area
Ped Derm 6:185–187, 1989; Ped Derm 73:31–33, 1983
Superior vena cava syndrome
RED FEET
AUTOIMMUNE DISEASES, AND DISEASES
OF IMMUNE DYSFUNCTION
Allergic contact dermatitis Caputo p.8, 2000
Bullous pemphigoid
Dermatomyositis
Goodpasture’s syndrome (annular erythematous macules)
AD 121:1442–1444, 1985
Graft vs. host reaction
Lupus erythematosus – systemic; reticulated telangiectatic
erythema of thenar and hypothenar eminences, finger pulps,
toes, lateral feet, and heels; bluish red with small white scars
Rook p.2473, 1998, Sixth Edition; discoid lupus erythematosus
JAAD 45:142–144, 2001
Pemphigus erythematosus
Rheumatoid arthritis
Rheumatoid neutrophilic dermatitis
Serum sickness Tyring p.369, 2002
Vasculitis
CONGENITAL ANOMALIES
Acrocyanosis Eichenfeld p.99, 2001
Syringomyelia
DEGENERATIVE DISEASES
Neurotrophic erythema
Thermally induced cutaneous vasodilatation in aging J Gerontol
48:M53–57, 1993
DRUG-INDUCED
RED FEET 569
Capecytabine (Xeloda) – acral dysesthesia syndrome
Cyclophosphamide and vincristine – acral erythema of
proximal nail fold and onychodermal band Cutis 52:43–44,
1993
Bromocriptine ingestion mimicking erythromelalgia Neurology
31:1368–1370, 1981
Chemotherapy-induced acral dysesthesia syndrome
(palmoplantar erythrodysesthesia syndrome) AD 131:202–206,
1995; JAAD 24:457–461, 1991; AD 122:1023–1027, 1986