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Dermatologic Differential Diagnosis.pdf. - Famona Site

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Corticosteroids – injected; topical fluorinated Rook p.3249,<br />

1998, Sixth Edition<br />

Etretinate – lightening of hair JAAD 34:860, 1996<br />

Hydroxychloroquine Ghatan p.248, 2002, Second Edition<br />

Mephenesin – lightening of hair Br Med J i:997–998, 1963<br />

Pityriasis rosea-like drug eruption<br />

Retinoids Ghatan p.248, 2002, Second Edition<br />

Toxic epidermal necrolysis – depigmentation after toxic<br />

epidermal necrolysis JAAD 10:106–109, 1984<br />

EXOGENOUS AGENTS<br />

Betel leaves – mottled hyperpigmentation evolving into<br />

confetti-like hypopigmentation JAAD 40:583–589, 1999<br />

Chemical leukoderma Rook p.1807, 1998, Sixth Edition<br />

Hydroquinone Rook p.3249, 1998, Sixth Edition<br />

Monobenzyl ether of hydroquinone<br />

Monoethyl ether of hydroquinone<br />

Monomethyl ether of hydroquinone<br />

p-isopropylcatechol<br />

p-methylcatechol<br />

p-tert-butylcatechol<br />

p-tert-butylphenol<br />

p-tert-amylphenol<br />

Mercaptoamines<br />

N,N′N′′-triethylenethiophosphoramide (thiotepa)<br />

Condoms – chemical hypopigmentation Rook p.2295, 1998,<br />

Sixth Edition<br />

Facial dressings of betel pepper (piper beetle)<br />

JAAD 40:583–589, 1999<br />

Irritant contact dermatitis to toothpaste<br />

Mercaptoethylamines Ghatan p.248, 2002, Second Edition<br />

INFECTIONS AND INFESTATIONS<br />

AIDS – premature canities Tyring p.367, 2002<br />

Herpes zoster Rook p.3249, 1998, Sixth Edition<br />

Leishmaniasis – post-kala-azar dermal leishmaniasis<br />

BJD 143:136–143, 2000; JAAD 34:257, 1996<br />

Leprosy – indeterminate – hypopigmented macules of face,<br />

arms, buttocks, or trunk Clin Inf Dis 32:930–937, 2001;<br />

Rook p.1222, 1998, Sixth Edition; tuberculoid or borderline<br />

tuberculoid – hypopigmented macule with dry, hairless<br />

anesthetic surface with fine wrinkling Int J Lepr Other Mycobact<br />

Dis 67:388–391, 1999; lepromatous leprosy Rook p.1224, 1998,<br />

Sixth Edition; borderline lepromatous Rook p.1227, 1998,<br />

Sixth Edition; dermatomal hypopigmented macular lesions<br />

Experientia 39:723–725, 1983<br />

Millipede secretions – red eyes and mahogany pigmentation<br />

with bullae; heal with hypopigmentation Rook p.1474, 1998,<br />

Sixth Edition<br />

Onchocerciasis – hypopigmented atrophic patches<br />

JAAD 45:435–437, 2001; Cutis 65:293–297, 2000;<br />

depigmentation and atrophy AD 140:1161–1166, 2004;<br />

Rook p.3249, 1998, Sixth Edition; AD 120:505–507, 1984<br />

Pediculosis – Vagabond’s leukoderma Ghatan p.248, 2002,<br />

Second Edition<br />

Pinta – generalized cutaneous phase – hypochromic papules<br />

and patches Rook p.1274, 1998, Sixth Edition; late secondary<br />

phase hypopigmented, depigmented hyperpigmented atrophic<br />

skin Rook p.1274, 1998, Sixth Edition; tertiary Cutis<br />

51:425–430, 1993<br />

Schistosomiasis – ectopic cutaneous granuloma – skin-colored<br />

papule, 2–3 mm; group to form mamillated plaques; facial<br />

hypopigmented plaque Dermatol Clin 7:291–300, 1989;<br />

BJD 114:597–602, 1986<br />

Streptocerciasis – Mansonella streptocerca – hypopigmented<br />

macules Derm Clinics 17:151–185, 1999<br />

Syphilis – secondary; as macular syphilid fades get<br />

depigmented macules with hyperpigmented background<br />

(leukoderma syphiliticum) on back and sides of neck (necklace<br />

of Venus) Rook p.1248–1249, 1998, Sixth Edition<br />

Tinea corporis<br />

Tinea imbricata- Trichophyton concentricum – hypopigmented<br />

plaques Clin Exp Dermatol 13:232–233, 1988; Trans R Soc Trop<br />

Med Hyg 78:246–251, 1984<br />

Tinea versicolor Textbook of Neonatal Dermatology, p.227,<br />

2001; Semin Dermatol 4:173–184, 1985<br />

Verrucae plana (flat warts) Tyring p.261, 2002<br />

Yaws – secondary – lenticular hypopigmented macules<br />

Rook p.1270, 1998, Sixth Edition<br />

INFILTRATIVE DISEASES<br />

Amyloidosis<br />

Langerhans cell histiocytosis<br />

INFLAMMATORY DISEASES<br />

Erythema multiforme<br />

Post-inflammatory hypopigmentation – in blacks, especially after<br />

dermatitis, sarcoidosis, leprosy, herpes zoster, tinea versicolor,<br />

cryotherapy, topical or injected corticosteroids Textbook of<br />

Neonatal Dermatology, p.364, 2001; Int J Dermatol 29:166–174,<br />

1990; vulvar Genital Skin Disorders, Fischer and Margesson,<br />

CV Mosby p.189,193, 1998<br />

Pseudolymphoma – CD8 + pseudolymphoma in HIV disease;<br />

widespread hypopigmentation JAAD 49:139–141, 2003<br />

Sarcoid AD 138:259–264, 2002; AD 123:1557–1562, 1987;<br />

Am J Med 35:67–89, 1963<br />

Sympathetic ophthalmia<br />

METABOLIC<br />

HYPOPIGMENTED PATCHES OR PLAQUES 281<br />

Acrodermatitis enteropathica with anorexia nervosa –<br />

hypopigmented hair JAMA 288:2655–2656, 2002<br />

Addison’s disease – vitiligo-like patches Rook p.1807, 1998,<br />

Sixth Edition<br />

Homocystinuria – skin and hair hypopigmentation JAAD<br />

40:279–281, 1999<br />

Hypopituitarism – diffuse loss of pigment Rook p.1807,2704,<br />

1998, Sixth Edition<br />

Hypothyroidism – pale, cold, scaly, wrinkled skin Rook p.1807,<br />

1998, Sixth Edition; JAAD 26:885–902, 1992<br />

Kwashiorkor – hypochromotrichia and hypopigmentation of skin<br />

Cutis 67:321–327, 2001; Cutis 51:445–446, 1993<br />

Liver disease, chronic – spotty hypopigmentation on back,<br />

buttocks, and thighs; may be in relation to spider telangiectasias<br />

Rook p.2725, 1998, Sixth Edition<br />

Malabsorption Ghatan p.248, 2002, Second Edition<br />

Pernicious anemia – vitiligo, canities Rook p.1783, 1998,<br />

Sixth Edition<br />

Phenylketonuria – phenylalanine hydroxylase deficiency; fair<br />

skin and hair Rook p.2645, 1998, Sixth Edition

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