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Dermatologic Differential Diagnosis.pdf. - Famona Site

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668 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1<br />

Linear IgA disease<br />

Morphea<br />

Pemphigoid vegetans AD 115:446–448, 1979<br />

Pemphigus foliaceus Cutis 63:271–274, 1999; <strong>Dermatologic</strong>a<br />

180:102–105, 1990<br />

Pemphigus vulgaris<br />

CONGENITAL LESIONS<br />

AD 90:160, 1964<br />

Associated anomalies of GU/GI tract<br />

Associated fistulas<br />

Choristia, periumbilical – intestinal mucosal cells; crusted,<br />

red perimbilical plaques Ann DV 105:601–606, 1978<br />

Congenital band<br />

Embryologic rests AD 123:105–110, 1987<br />

Umbilical hernia – omphalocele Postgrad Med 57:635–639,<br />

1981; herniation of umbilical cord Rook p.3164, 1998,<br />

Sixth Edition<br />

Granulation tissue<br />

Omphalomesenteric duct remnants – cutaneous remnants of<br />

the omphalomesenteric duct – completely patent duct – red<br />

nodule with a fistula with fecal discharge or intestinal prolapse<br />

Am J Surg 88:829–834, 1954; patent peripheral portion – red,<br />

polypoid nodule (ectopic gastrointestinal mucosa) (umbilical<br />

polyp); discharges mucus; resemble prolapsed urachal mucosa<br />

and talc granuloma; fistulae, cysts Ped Derm 4:341–343, 1987;<br />

AD 90:463–470, 1964<br />

Patent urachal duct AD 90:160–165, 1964<br />

Persistent vascular anomalies<br />

Persistent vitelline duct and polyp – fecal or mucoid discharge<br />

<strong>Dermatologic</strong>a 150:111–115, 1975<br />

Prolapsed urachal mucosa<br />

Umbilical granuloma – most common umbilical mass Textbook<br />

of Neonatal Dermatology, p.95,132, 2001<br />

Urachal and vascular abnormalities (ectopic transitional<br />

epithelium of bladder) – urachal remnants with cyst, sinus, or<br />

fistula Textbook of Neonatal Dermatology, p.132, 2001; Cutis<br />

62:83–84, 1998; complete patency of the urachus – urine<br />

emanating from umbilicus; nodule Ped Clin N Am 6:1085–1116,<br />

1959; urachal cyst (partial patency of the urachus) – tender<br />

midline swellings between the umbilicus and symphysis pubis<br />

Br J Urol 28:253–256, 1956; urachal sinus<br />

Yolk sac remnant – umbilico-ileal fistula<br />

EXOGENOUS AGENTS<br />

Foreign body granuloma AD 139:1497–1502, 2003; secondary<br />

infection Rook p.3164, 1998, Sixth Edition<br />

Irritant dermatitis<br />

Talc granuloma – older individuals BJD 83:151–156, 1970<br />

Umbilical ring<br />

INFECTIONS<br />

Candidiasis – candidal intertrigo Rook p.3164, 1998,<br />

Sixth Edition; candidal sepsis<br />

Cellulitis<br />

Chigger mite bites Ghatan p.101, 2002, Second Edition<br />

Clostridial cellulitis AD 113:683–684, 1977<br />

Cysticercosis J Trop Med Hyg 88:25–29, 1985<br />

Diphtheria – superficial round ulcer with overhanging edge; gray<br />

adherent membrane; later edge thickens and becomes raised<br />

and rolled; umbilicus, post-auricular, groin, finger or toe web;<br />

heals with scarring; crusts around nose and mouth with faucial<br />

diphtheria Schweiz Rundsch Med Prax 87:1188–1190, 1998;<br />

Postgrad Med J 72:619–620, 1996; Am J Epidemiol<br />

102:179–184, 1975<br />

Erythrasma<br />

Herpes simplex<br />

Herpes zoster<br />

Impetigo<br />

Lyme disease<br />

Molluscum contagiosum<br />

Mycobacterium tuberculosis – granuloma Ghatan p.101, 2002,<br />

Second Edition<br />

Omphalitis – neonatal omphalitis and cellulitis;<br />

coagulase-negative staphylococcus Textbook of Neonatal<br />

Dermatology, p.184, 190, 2001; Arch Derm 113:683, 1977<br />

Pediculosis pubis<br />

Pseudomonas Rook p.3164, 1998, Sixth Edition<br />

Rubella, congenital – hyperpigmentation of forehead, cheeks,<br />

umbilical area J Pediatr 71:311–331, 1967<br />

Scabies – periumbilical papules Rook p.1460–1461, 1998,<br />

Sixth Edition<br />

Schistosomiasis – ectopic cutaneous granuloma – periumbilical<br />

papules skin-colored papule, 2–3-mm; group to form mamillated<br />

plaques; nodules develop with overlying dark pigmentation,<br />

scale, and ulceration; periumbilical Dermatol<br />

Clin 7:291–300, 1989; BJD 114:597–602, 1986; Ann DV<br />

107:759–767, 1980; Br J Vener Dis 55:446–449, 1979<br />

Staphylococcus aureus Rook p.3164, 1998, Sixth Edition<br />

Staphylococcal scalded skin syndrome<br />

Strongyloidiasis – periumbilical thumb-print purpura<br />

JAAD 256:1170–1171, 1986<br />

Tinea corporis<br />

Urachal abscess J Clin Ultrasound 19:203–208, 1991<br />

Verruca vulgaris Genitourin Med 70:49–50, 1994<br />

INFLAMMATORY DISEASES<br />

Crohn’s disease – metastatic Clin Exp Dermatol 21:318–319,<br />

1996<br />

Cullen’s sign – periumbilical purpura; acute pancreatitis,<br />

ruptured ectopic pregnancy, perforated duodenal ulcer<br />

Rook p.3165, 1998, Sixth Edition; Br Med J i:154, 1971<br />

Deep umbilicus – purulent umbilical drainage<br />

JAAD 44:687–688, 2001<br />

Endometriomas (32% of all umbilical tumors, most common);<br />

cutaneous endometrioma J Derm Surg 20:693–695, 1994;<br />

South Med J 70:147–152, 1977; AD 112:1435–1436, 1976;<br />

JAMA 191:167, 1965 Erythema multiforme<br />

Funisitis – inflammation of the umbilical cord or stump;<br />

increased secretions and/or foul odor Textbook of Neonatal<br />

Dermatology, p.184, 2001<br />

Pilonidal sinus of umbilicus (hair sinus) – pain, tenderness, and<br />

discharge in hirsute men Cutis 62:83–84, 1998; J Fam Pract<br />

29:205–209, 1989<br />

Hidradenitis suppurativa<br />

Necrotizing fasciitis, retroperitoneal – periumbilical<br />

erythema JAAD 53:527–528, 2005; Crit Care<br />

Med 29:1071–1073, 2001

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