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16 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1<br />

polyethylene glycol-coated liposomal doxorubicin AD<br />

136:1475–1480, 2000; docetaxel BJD 142:808–811, 2000;<br />

cisplatin BJD 139:750–751, 1998; etoposide Cancer Chemother<br />

Pharmacol 34:181, 1994; cytarabine JAAD 24:1023–1025,<br />

1991; tegafur Acta DV 77:80–81, 1997; AD 131:364–365, 1995;<br />

5-fluorouracil; capecytabine (Xeloda)<br />

Calcitonin<br />

Docataxel extravasation AD 141:1326–1327, 2005<br />

Doxycycline phototoxicity; photo-onycholysis<br />

Drug-induced erythema of proximal nail fold and onychodermal<br />

band due to cyclophosphamide and vincristine Cutis 52:43–44,<br />

1993<br />

Drug rash<br />

Eccrine squamous syringometaplasia – secondary to<br />

chemotherapy AD 133:873–878, 1997; JAAD 26:284, 1992<br />

Erythromelalgia – calcium channel blockers (felodipine,<br />

nifedipine, amlodipine, diltiazem) JAAD 45:323–324, 2001; BJD<br />

136:974–975, 1997<br />

Fixed drug eruption<br />

Hydroxyurea AD 135:818–820, 1999; AD 111:183–187, 1975;<br />

dermatomyositis-like rash JAAD 49:339–341, 2003<br />

Methotrexate photorecall<br />

Nifedipine – erythromelalgia-like erythema Br Med J<br />

298:1252–1253, 1989<br />

Piroxicam photodermatitis<br />

Prostacycline – continuous infusion<br />

Quinolones Therapie 51:601–602, 1996<br />

Tetracycline-induced porphyria cutanea tarda-like syndrome<br />

EXOGENOUS AGENTS<br />

Contact dermatitis – capsicum (red peppers); red hands and red<br />

lips Cutis 72:21–23, 2003<br />

INFECTIONS AND INFESTATIONS<br />

Cellulitis/erysipelas<br />

Erysipeloid<br />

Erythrasma<br />

Felon<br />

Fusarium solani – digital cellulitis Rook p.1375, 1998, Sixth Edition<br />

Hepatitis C – periungual erythema JAAD 46:S159–160, 2002<br />

Acute HIV infection Cutis 40:171–175, 1987<br />

Human herpesvirus 8 – relapsing inflammatory syndrome; fever,<br />

lymphadenopathy, splenomegaly, edema, arthrosynovitis,<br />

exanthem of hands, wrists, and elbows NEJM 353:156–163,<br />

2005<br />

Infectious eczematoid dermatitis<br />

Janeway lesion – faint red macular lesions of thenar and<br />

hypothenar eminences NEJM 295:1500–1505, 1976<br />

Lepromatous leprosy<br />

Lymphogranuloma venereum – red nails, red lunulae Ghatan<br />

p.79,80, 2002, Second Edition<br />

Majocchi’s granuloma<br />

Measles, atypical Tyring p.410, 2002<br />

Parvovirus B19 (erythema infectiosum) Hum Pathol<br />

31:488–497, 2000; including papular pruritic petechial gloves<br />

and socks syndrome – hands, wrists, feet, and ankles; acral<br />

edema and erythema as initial signs BJD 151:201–206, 2004;<br />

Tyring p.300–301, 2002; Cutis 54:335–340, 1994; oral ulceration<br />

AD 120:891–896, 1984<br />

Scarlet fever<br />

Seal finger – painful, swollen red finger; synovitis J Rheumatol<br />

13:647–648, 1986<br />

Syphilis – primary or secondary<br />

Tinea manuum<br />

Tinea versicolor<br />

Toxic shock syndrome, either staphylococcal or streptococcal –<br />

erythema and edema of the palms and soles JAAD<br />

39:383–398, 1998<br />

Viral exanthem<br />

INFILTRATIVE DISEASES<br />

Mastocytosis<br />

INFLAMMATORY DISEASES<br />

Erythema multiforme; Stevens–Johnson syndrome<br />

Panniculitis<br />

Toxic epidermal necrolysis<br />

METABOLIC DISORDERS<br />

Acrodermatitis enteropathica; acquired zinc deficiency<br />

Chronic obstructive pulmonary disease (COPD) – red lunulae<br />

Ghatan p.80, 2002, Second Edition<br />

Congestive heart failure – red nails, lunulae Ghatan p.79, 2002,<br />

Second Edition<br />

Hyperthyroidism<br />

Myxedema<br />

Liver disease, chronic – palmar erythema<br />

Neuropathic – alcoholic, diabetic, lepromatous.<br />

Pellagra<br />

Polycythemia vera – red lunulae Ghatan p.79, 2002, Second<br />

Edition<br />

Porphyria – congenital erythropoietic porphyria Semin Liver<br />

Dis 2:154–63, 1982<br />

Thrombocythemia – livedo reticularis, acrocyanosis,<br />

erythromelalgia, gangrene, pyoderma gangrenosum Leuk<br />

Lymphoma 22 (Suppl 1):47–56, 1996; Br J Haematol<br />

36:553–564, 1977; AD 87:302–305, 1963<br />

Vitamin B6 (pyridoxine) deficiency – acrodynia Rook p.2658,<br />

1998, Sixth Edition; J Lab Clin Med 42:335–337, 1953<br />

NEOPLASTIC DISORDERS<br />

Atrial myxoma<br />

Enchondromas – red nails Ghatan p.79, 2002, Second Edition<br />

Hodgkin’s disease – periungual erythema JAAD 46:S159–160,<br />

2002<br />

Kaposi’s sarcoma – classical or HIV-associated<br />

Metastatic gastric carcinoma JAAD 27:117–118, 1992; also<br />

breast, lung, kidney, colon (mimic felon, whitlow, paronychia)<br />

PARANEOPLASTIC DISEASES<br />

Bazex syndrome<br />

PHOTODERMATOSES<br />

Creosote phototoxicity<br />

Drug-induced phototoxicity

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