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Dermatologic Differential Diagnosis.pdf. - Famona Site

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Epidermolysis bullosa acquisita<br />

IgA pemphigus – resembles subcorneal pustular dermatosis<br />

AD 138:744–746, 2002; JAAD 43:546–549, 2000<br />

Lichenoid reactions with antibodies to desmoplakins I and II –<br />

vulvar erythema and perianal erythema JAAD 48:433–438,<br />

2003<br />

Linear IgA disease (chronic bullous disease of childhood) –<br />

intertriginous and perigenital JAAD 51:95–98, 2004<br />

Lupus erythematosus – discoid LE, neonatal LE,<br />

telangiectasias in neonatal LE<br />

Pemphigoid vegetans – vegetating plaque JAAD 30:649–650,<br />

1994; JAAD 29:293–299, 1993; AD 115:446–448, 1979<br />

Pemphigus foliaceus<br />

Pemphigus vegetans Rook p.1857–1858, 1998, Sixth Edition;<br />

AD 114:627–628, 1978<br />

Pemphigus vulgaris Cutis 61:21–24, 1998; Rook p.3168, 1998,<br />

Sixth Edition<br />

Scleroderma – axillary verrucous pigmentation resembling<br />

acanthosis nigricans Br Med J ii:1642–1645, 1966<br />

DRUGS<br />

Doxorubicin – polyethylene glycol-coated liposomal doxorubicin<br />

AD 136:1475–1480, 2000<br />

Etretinate ulcers of intertrigenous areas Cutis 45:111–3, 1990<br />

Fixed drug eruption Dtsch Med Wochenschr 125:1260–1262,<br />

2000<br />

Interleukin-1 alpha followed by ifosfamide, carboplatin, and<br />

etoposide – erosive intertrigo JAAD 35:705–709, 1996<br />

Lithium carbonate – axillary subcorneal pustular dermatosis<br />

Cutis 41:165–166, 1988<br />

Periorificial dermatitis around vulva due to topical steroids<br />

Syringosquamous metaplasia – red, blanching, crusted<br />

papules; due to cancer chemotherapy BJD 134:984–986, 1996;<br />

AD 126:73–77, 1990; Am J Dermatopathol 12:1–6, 1990<br />

EXOGENOUS AGENTS<br />

Irritant contact dermatitis – axillary dermatitis from deodorant<br />

sticks; irritant diaper (napkin) dermatitis, peristomal and perianal<br />

dermatitis Textbook of Neonatal Dermatology, p.251, 2001;<br />

Rook p.729, 1998, Sixth Edition<br />

INFECTIONS AND/OR INFESTATIONS<br />

Amebiasis – phagedenic necrosis, fistulae,<br />

pseudoelephantiasis; granulomas, condylomatous masses<br />

Dermatol Trop 2:129–136, 1963<br />

Botryomycosis JAAD 9:428–434, 1983<br />

Candidiasis – flexural candidiasis Rook p.1342,3212, 1998,<br />

Sixth Edition; Clin Obstet Gynecol 24:407–438, 1981; diaper<br />

dermatitis Textbook of Neonatal Dermatology, p.252, 2001;<br />

erosio interdigitalis blastomycetica and chronic mucocutaneous<br />

candidiasis; multiple entities can show changes of chronic<br />

mucocutaneous candidiasis including Nezelof syndrome,<br />

Swiss-type agammaglobulinemia, DiGeorge’s syndrome,<br />

hyper-IgE syndrome, mucoepithelial dysplasia<br />

Chancroid resembling granuloma inguinale<br />

Condyloma acuminata<br />

Cytomegalovirus diaper dermatitis – a cause of perineal<br />

ulcers and diaper dermatitis AD 127:396–398, 1991;<br />

JAAD 24:857–863, 1991<br />

INTERTRIGO, INCLUDING DIAPER DERMATITIS 293<br />

Dermatophilus congolensis – due to contact with infected<br />

animals BJD 145:170–171, 2001<br />

Dermatophytosis – tinea corporis, tinea cruris – Trichophyton<br />

rubrum, Epidermophyton floccosum Semin Dermatol<br />

4:185–200, 1985; tinea pedis – bullous Rook<br />

p.1300–1301,1309, 1998, Sixth Edition; Trichophyton rubrum<br />

and Epidermophyton diaper dermatitis Clin Ped 26:149–151,<br />

1987; Trichophyton verrucosum (zoophilic fungus of cattle)<br />

diaper dermatitis Ped Derm 10:368–369, 1993<br />

Diphtheria – superficial round ulcer with overhanging edge; gray<br />

adherent membrane; later edge thickens and becomes raised<br />

and rolled; umbilicus, post-auricular, groin, finger or toe web;<br />

heals with scarring; crusts around nose and mouth with faucial<br />

diphtheria Schweiz Rundsch Med Prax 87:1188–1190, 1998;<br />

Postgrad Med J 72:619–620, 1996; Am J Epidemiol<br />

102:179–184, 1975<br />

Enterobiasis (Enterobius vermicularis) – perineal intertrigo<br />

Rook p.1390, 1998, Sixth Edition<br />

Erythrasma – intertriginous and perigenital; Corynebacterium<br />

minutissimum; red to brown irregularly shaped and sharply<br />

marginated scaly and slightly creased patches of groin, axillae,<br />

intergluteal, submammary flexures, toe webs; coral-red<br />

fluorescence with Wood’s light examination due to<br />

coproporphyrin; toe clefts are most frequent location; acanthosis<br />

nigricans and normal follicular openings of face and trunk may<br />

show coral pink fluorescence Rev Infect Dis 4:1220–1235, 1982<br />

Gram-negative web space infections Caputo p.140–141, 2000<br />

Granuloma inguinale Rook p.3168, 1998, Sixth Edition<br />

Hand, foot and mouth disease – diaper rash of hand foot and<br />

mouth disease Dialogues in Dermatol, Nov. 2001<br />

Herpes simplex infection Rook p.3168, 1998, Sixth Edition;<br />

linear intertrigo<br />

HTLV-1 infection – infective dermatitis of scalp, eyelid margins,<br />

perinasal skin, retro-auricular areas, axillae, groin; generalized<br />

papular dermatitis Lancet 336:1345–1347, 1990; BJD<br />

79:229–236, 1967; BJD 78:93–100, 1966<br />

Impetigo contagiosa<br />

Mycobacterium haemophilum – inguinal ulcer AD 138:229–230,<br />

2002<br />

Mycobacterium tuberculosis – tuberculosis verrucosa cutis<br />

Rook p.3168, 1998, Sixth Edition; periorificial tuberculosis<br />

JAAD 51:492–493, 2003<br />

North American blastomycosis Rook p.3168, 1998, Sixth Edition<br />

Parvovirus B19 infection – accentuation in folds<br />

Pediculosis<br />

Pseudomonas – toe web space maceration and ulceration<br />

AD 107:71–74, 1973<br />

Recurrent toxin-mediated perineal erythema – associated<br />

with pharyngitis due to Staphylococcus aureus or Streptococcus<br />

pyogenes AD 132:57060, 1996<br />

Scabies<br />

Scarlet fever – perigenital dermatitis<br />

Schistosomiasis – phagedenic necrosis, fistulae,<br />

pseudoelephantiasis; granulomas, condylomatous masses<br />

Rook p.3166, 1998, Sixth Edition<br />

Seabather’s eruption – on Long Island, causative organism<br />

is the planula larvae of the sea anemone Edwardsiella lineata;<br />

in Florida, planula larvae of the jellyfish Linuche unguiculata<br />

JAAD 30:269–270, 1994; NEJM 329:542–544, 1993<br />

Staphylococcus aureus pustulosis (folliculitis)<br />

Streptococcal intertrigo – neck in chubby babies Pediatrics<br />

112:1427–1429, 2003; post-auricular area, groin, perianal<br />

cellulitis BJD 74:323–325, 1962

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