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laura briggs<br />
though <strong>the</strong>ir grades were apparently based on <strong>the</strong>ir participation in <strong>the</strong><br />
study. No meaningful data were collected. Although <strong>the</strong> mental patient<br />
group could be more successfully monitored daily, female contraceptive<br />
effect was diffi cult to gauge in a population that was presumed not to<br />
be heterosexually active. These studies, <strong>the</strong>n, offered little except <strong>the</strong><br />
general information that <strong>the</strong>se steroidal compounds posed no immediately<br />
appreciable systemic danger to users. However, <strong>the</strong>y once again<br />
raised <strong>the</strong> issue of side effects; as with Rock’s infertile patients, several<br />
complained of dizziness, nausea, headache, and menstrual irregularities<br />
(McLaughlin, 1982; Marks, 1998; Oudshoorn, 1994; Ramírez de<br />
Arellano & Seipp,1983; Vaughan, 1970; Pincus, 1958).<br />
Researchers also followed ano<strong>the</strong>r lead in this series of cases: steroids<br />
had previously been documented to cause male infertility, too. Among<br />
<strong>the</strong> psychotic men in Massachusetts, urine samples and biopsied testicular<br />
tissue showed—albeit inconclusively—that <strong>the</strong> steroidal compound <strong>the</strong>y<br />
tested stopped sperm production (Pincus, 1957). The implications of<br />
this were never pursued; no effort was made to develop or fur<strong>the</strong>r test<br />
<strong>the</strong> Pill as a contraceptive for men. Something about giving steroidal<br />
compounds to men was less appealing than controlling women’s fertility.<br />
This choice was probably overdetermined; several explanations come to<br />
mind: McCormick and Sanger, as funders, were interested specifi cally<br />
in a female-controlled method and <strong>the</strong> discourse of overpopulation<br />
targeted women. However, ano<strong>the</strong>r issue was noted that probably also<br />
contributed: one of <strong>the</strong> male mental patients was described by a nurse<br />
as acting “effeminate” during treatment. Although no physiologic effects<br />
such as breast development were reported, <strong>the</strong> suggestion that <strong>the</strong>se<br />
steroids could make men act like women, or like homosexuals, was<br />
apparently enough. What behavior a psychotic man who was unable<br />
to cooperate with researchers could have exhibited to make him seem<br />
“feminine” to <strong>the</strong> nursing staff is diffi cult to imagine. But such possible<br />
side effects dovetailed with <strong>the</strong> perception of hormones as powerfully<br />
<strong>the</strong> “essence” of maleness or femaleness and seem to have been suffi cient<br />
to deter fur<strong>the</strong>r such research.<br />
The next round of testing in 1956 involved a much larger series of<br />
cases, and <strong>the</strong>se, too, were organized in Puerto Rico. Two groups of<br />
women, one residents of a housing project in Río Piedras, and ano<strong>the</strong>r,<br />
patients of Ryder Hospital (usually, women turned down for sterilization<br />
because <strong>the</strong>y had fewer than <strong>the</strong> three children required (Satterthwaite<br />
& Gamble, 1962) were enrolled in an effort to understand whe<strong>the</strong>r <strong>the</strong><br />
Pill prevented pregnancy, and whe<strong>the</strong>r it was acceptable and could be<br />
used effectively by those who “most needed” contraception, specifi cally<br />
working-class women living in “overpopulated” and “underdeveloped”