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the Female Body GOVERNING

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2<br />

Beyond Pill Scares?<br />

Online Discussion on Genetic Thrombophilia<br />

and Gendered Contradictions<br />

of Personalized Medicine<br />

PAULA SAUKKO<br />

Loughborough University<br />

In October 1995 all U.K. doctors received a letter from <strong>the</strong><br />

Committee on <strong>the</strong> Safety of Medicines regarding a study that had<br />

identified a correlation between <strong>the</strong> use of third-generation oral contraceptives<br />

and <strong>the</strong> occurrence of deep vein thrombosis (DVT), which<br />

was widely reported in <strong>the</strong> media. Afterward <strong>the</strong> medical community,<br />

blaming <strong>the</strong> committee and sensationalist media, reported a rise in <strong>the</strong><br />

number of abortions and births (Drife, 1996). This 1995 “Pill scare”<br />

was not <strong>the</strong> first of its kind. The association between drugs containing<br />

estrogen and DVT had been reported in 1961 (Jordan, 1961), nearly<br />

coinciding with <strong>the</strong> mass release of <strong>the</strong> Pill in 1960 and resulting<br />

in major controversy, which provoked, among o<strong>the</strong>rs, acidic feminist<br />

remarks, which Briggs discusses in this volume.<br />

In 1994 <strong>the</strong> University of Leiden identified a gene alteration that<br />

increased, even if not dramatically, an individual’s susceptibility to DVT<br />

(Bertina et al., 1994). Some doctors were soon suggesting that women<br />

going on oral contraceptives be tested for this “factor V Leiden” (FVL)<br />

alteration. The discovery of FVL promised to resolve <strong>the</strong> mystery of<br />

<strong>the</strong> Pill and blood clots, which had made women of reproductive age<br />

nervous by identifying <strong>the</strong> minority of women who were likely to have<br />

a DVT while on <strong>the</strong> Pill. It seemed one of <strong>the</strong> first success stories in<br />

preventive genomics, which had sought to identify “at-risk” individuals<br />

and to help <strong>the</strong>m to prevent common diseases from cardiovascular<br />

disease and diabetes to cancer (e.g., Collins, Green, Guttmacher, &<br />

Guyer, 2003; Department of Health, 2003; Weinshillboum, 2003).<br />

Thrombophilia was later also discovered to be associated with miscarriage<br />

and stillbirth. It was suggested that testing could help identify<br />

40

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