You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
The Pill in Puerto Rico and <strong>the</strong> Mainland United States 177<br />
dropped out because of side-effects (1957), while Satterthwaite (1957,<br />
1958) believed that <strong>the</strong>re were signifi cant, potentially precancerous<br />
changes in <strong>the</strong> cervices of patients using <strong>the</strong> Pill—<strong>the</strong>y had had Third<br />
World overpopulation in mind. When <strong>the</strong> FDA presented reports of<br />
thromboembolis in British and North American women using <strong>the</strong> Pill<br />
to <strong>the</strong>m, <strong>the</strong> Pill’s defenders continued to cite “overpopulation” as <strong>the</strong><br />
major reason to continue to support it.<br />
In my research, I followed this debate through several organizations,<br />
but found one particularly revealing and candid source: <strong>the</strong> editor’s fi les<br />
for Rockefeller University’s Medical Letter. The Medical Letter was sent to<br />
physicians and described new drugs, questions about side effects, and<br />
controversies over older ones. In <strong>the</strong> fi rst years of <strong>the</strong> 1960s, following<br />
FDA approval of <strong>the</strong> Pill as a contraceptive, <strong>the</strong> Medical Letter’s editor,<br />
Harold Aaron, sent a series of drafts of articles out about <strong>the</strong> Pill to all<br />
<strong>the</strong> major players in <strong>the</strong> fi eld—policy makers, researchers, corporations,<br />
and physicians. The reviewers of <strong>the</strong>se articles were and, unfortunately,<br />
must remain anonymous because of restrictions attached to <strong>the</strong> papers<br />
by <strong>the</strong>ir donor and enforced by <strong>the</strong> archive. These reviewers were<br />
not, however, obscure; <strong>the</strong>y encompassed some of <strong>the</strong> most signifi cant<br />
researchers and advocates in <strong>the</strong> fi eld. Toge<strong>the</strong>r, <strong>the</strong>y produce a fascinating<br />
ensemble of voices and suggest a great deal about what questions<br />
and arguments seemed possible to those involved in making decisions<br />
about <strong>the</strong> Pill.<br />
In 1960, <strong>the</strong> Medical Letter ran an article that was warmly positive<br />
about <strong>the</strong> Pill. Its tone was one of certainty; it assured readers that a<br />
considerable amount was known about <strong>the</strong> effect of estrogen-progestin<br />
oral contraceptives. The only hint of concern about <strong>the</strong> effects of <strong>the</strong>se<br />
drugs was that one reviewer insisted that a line that described <strong>the</strong> Pill<br />
as being “as safe as <strong>the</strong> condom and <strong>the</strong> diaphragm” be changed to “as<br />
effective as,” arguing that unknown side effects were still possible.<br />
By 1962 and 1963, however, <strong>the</strong> Medical Letter was grappling with how<br />
to report 28 cases of thromboembolic disease, including one death,<br />
which had been reported to <strong>the</strong> FDA and linked with <strong>the</strong> use of <strong>the</strong><br />
Pill. Articles in <strong>the</strong> newsletter tried to strike a balance between warning<br />
of potentially serious effects on <strong>the</strong> one hand, but on <strong>the</strong> o<strong>the</strong>r not<br />
overreacting to anecdotal reports when <strong>the</strong>re was little agreement over<br />
what <strong>the</strong> rate of clotting disorders should be in <strong>the</strong> general population,<br />
and whe<strong>the</strong>r 28 out of approximately 1 million users was too high (or<br />
whe<strong>the</strong>r <strong>the</strong>re were o<strong>the</strong>rs who had not been recorded as having to do<br />
with <strong>the</strong> Pill). However, guarded language met with little approval by<br />
ei<strong>the</strong>r side. One article reproduced a pharmaceutical company’s advice<br />
to physicians that <strong>the</strong>y “should be alert to <strong>the</strong> possible occurrence