2010-2011 UF Graduate Catalog (PDF Format) - Graduate School ...

University of Florida Graduate School
http://test.gradschool.ufl.edu/catalog/current-catalog/FOI/PH01.htm[9/15/2010 4:08:13 PM]
of recombinant DNA technology needed to interact and
communicate as a pharmaceutical scientist in biotechnology.
Recombinant peptide and protein drugs including protein
purification, stability, quality control, and dosage form design.
Offered fall term.
PHA 6115: Equilibria, Complexations, and Interactions of
Drugs (3) Models for drug interactions in solution. Physical
chemistry characteristics of drugs and their complexes in
pharmaceutical systems.
PHA 6116: In Vivo and In Vitro Stability of Drugs (3) Effects of
various disease states, age, genetic differences, stress, nutrition,
and drug interactions on drug metabolism. Offered fall term in
even-numbered years.
PHA 6118: Molecular Diversity (2) Combinatorial and high
throughput methods to generate leads for drug discovery and
accelerated drug development.
PHA 6125: Pharmacokinetics and Biopharmaceutics (3)
Compartmental analysis with computers. Offered spring term in
even-numbered years.
PHA 6170C: Pharmaceutical Product Formulation (3) Rationale
and design of pharmaceutical dosage forms. Offered fall term in
odd-numbered years.
PHA 6183: Pharmaceutical Gene Delivery (3) Designed for
graduate students researching gene delivery. Lectures on vector
design and construction including review of related molecular
biology and cell biology. Lectures on gene delivery systems (both
viral and nonviral vectors) and their applications. Recent progress of
gene therapy for human diseases including student presentations.
Offered in odd-numbered years.
PHA 6185: Pharmaceutical Drug Development (3) Prereq:
consent of instructor. Open to graduate students and advanced
Pharm.D. students. Drug development from discovery to postmarket
surveillance. Good manufacturing process (GMP), good
clinical practice (GCP), and good laboratory practice (GLP);
intellectual property, regulatory agencies, generic approvals, and
case studies.
PHA 6416: Pharmaceutical Analysis I (3) Theory and
applications of relevant analytical techniques for analysis of drugs in
biological samples. Offered spring term in odd-numbered years.
PHA 6427: Pharmacogenetics of Drug Metabolism(2)
Examination of factors that affect drug disposition and response
including genetics, as well as, additional factors such as
environment, diet, age, and concurrent drug therapy and health
status. Students will acquire an understanding of
pharmacogenetics/pharmacogenomics in the context of variability in
drug disposition and the application of pharmacogenetics to drug
development and drug treatment.
PHA 6440: Seminar in Drug Discovery (1; max: 8) Weekly
presentations of research topics related to drug design and
discovery. S/U option.
PHA 6449: Pharmacogenomics (2) Prereq: biochemistry, PHA