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262. Puigserver, P., G. Adelmant, Z. Wu, M. Fan, J. Xu, B. O'Malley, and B. M. Spiegelman.
Activation of PPARgamma Coactivator-1 through transcription factor docking. Science 286: 1368­
1371,1999.
263. Puigserver, P., Z. Wu, C. W. Park, R. Graves, M. Wright, and B. M. Spiegelman. A coldinducible
coactivator of nuclear rceptors Iinked to adaptive thermogenesis. Ce1192: 829-839, 1998.
264. Reddy, B. S., and Y. Maeura. Tumor promotion by dietary fat in azomethane-induce colon
carcinogenesis in female F344 rats: influence of amount and source of dietary fat. J Nat! Cancer Inst
72: 745-750,1984.
265. Reddy, B. S., and S. Sugie. Effect of different levels of ro-3and ro-6 fatty acids on
azoxymethane-induced colon carcinogenesis in F344 rats. Cancer Res 48: 6642-6647,1988.
266. Reddy, J. K. Carcinogenicity of peroxisome proliferators: evaluation and mechanisms.
Biochem. Soc. Trans. ?: 92-94, 1990.
267. Reed, B. C., and M. D. Lane. Insu lin receptor synthesis and turnover in differentiating 3T3-L1
preadipocytes. Proc Nat! Acad Sci USA 77: 285-289, 1980.
268. Reginato, M. J., S. L. Krakow, S. T. Bailey, and M. A Lazar. Prostaglandins promote and
block adipogenesis through opposing effets on peroxisome proliferator-activated receptor gamma. J
Biol Chem 273: 1855-1858, 1998.
269. Reynolds, E. The use of lead citrate at high pH as an electron-opaque stain in electron
microscopy. J Cell Biol 17: 208-213, 1963.
270. Ricote, M., J. Huang, L. Fajas, A Li, J. Welch, J. Najib, J. L. Witzum, J. Auwerx, W. Palinski,
and C. K. Glass. Expression of PPARy in human atherosclerosis and regulation in macrophages by
colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci USA 95: 7614­
7619,1998.
271. Ricote, M., A C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass. The peroxisome proliferator
activated receptor-y is a negative regulator of macrophage activation. Nature 391: 79-82, 1998.
272. Rijsewijk, F., M. Schuermann, E. Wagenaar, P. Parren, D. Weigel, and R. Nusse. The
Drosophilia homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene
wingless. Cel/50: 649-657, 1987.
273. Rivier, M., 1. Safonova, P. Lebrun, C. E. Griffiths, G. Ailhaud, and E. Michel. Differentiai
expression of peroxisome proliferator-activated receptors subtypes during differentiation of human
keratinocytes. J Invest Oermato/111: 1116-1121, 1998.
274. Roberts, R. A, N. H. James, N. J. Woodyatt, N. Maddonald, and J. D. Tugwood. Evidence for
the suppression of apoptosis by the peroxisome proliferator activated receptor alpha. Carcinogenesis
19: 43-48, 1998.
275. Robine, S., C. Huet, R. MolI, C. Sahuquillo-Merino, E. Coudrier, A Zweibaum, and D. Louvard.
Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells. Proc Nat!
Acad Sci USA 82: 8488-8492, 1985.
276. Rodriguez, J. C., G. Gil-Gomez, F. G. Hegardt, and D. Haro. Peroxisome proliferator-activated
receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-coA synthase gene by
fatty acids. J. Biol. Chem. 269: 18767-18772, 1994.
277. Roelink, H., E. Wagenaar, S. L. d. Silva, and R. Nusse. Wnt-3, a gene activated by proviral
insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in
mouse embryos and adult brain. Proc Nat! Acad Sci USA 87: 4519-4523, 1990.
278. Roels, F., M. Espeel, M. Pauwels, D. deCraemer, H. J. A. Egberts, and N. V. d. Spek. Different
types of peroxisomes in human duodenal epithelium. Gut 32: 858-865, 1991.
279. Rokos, C. L., and B. J. Ledwith. Peroxisomes proliferators activate extracellular signalregulated
kinases in immortalized mouse liver cells. J Biol Chem 272: 13452-43457, 1997.
280. Ross, S., N. Hemati, K. Longo, C. Bennett, P. Lucas, R. Erickson, and O. MacDouglas.
Inhibition of adipogenesis by Wnt siganling. Science 289: 950-953, 2000.
281. Rousset, M., M. Laburthe, M. Pinto, G. Chevalier, C. Rouyer-Fessard, E. Dussaulx, N. Boige,
J. L. Brun, and A. Zweibaum. Enterocytic differentiation and glucose utilization in the human tumor cell
line Caco-2 : modulation by forskolin. J. Cel/. Physiol. 123: 1269-1273, 1985.
282. Rubin, D., E. Swietlicki, K. Roth, and J. Gordon. Use of fetal intestinal isografts from normal
and transgenic mice to study the programming of positionnai information along the duodenal-to-colonic
axis. J Biol Chem 267: 15122, 1992.
283. Rubinfeld, B., 1. Albert, E. Porfiri, C. Fiol, S. Munemitsu, and P. Polakis. Binding of GSK3~ to
the APC-~-catenin complex and regulation of complex assembly. Science 272: 1023-1026, 1996.
284. Saez, E., P. Tontonoz, M. C. Nelson, J. G. Alvarez, U. T. Ming, S. M. Baird, V. A. Thomazy,
and R. M. Evans. Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nat
Med 4: 1058-1061, 1998.
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