Ce document numérisé est le fruit d'un long travail approuvé par le ...

285. Sakanaka, C., P. Leong, L. Xu, S. Harrison, and L. Williams. Casein kinase-1 epsilon in the
wnt pathway: regulation of ~-catenin function. Proc Nat! Acad Sci USA 96: 12548-12552, 1999.
286. Salenius, P. On the ontogenesis of the human gastric epithelial cells. Acta Anat 46: 1-75,
1962.
287. Sambrook, J., E. F. Fritsch, and T. Maniatis. Molecular cloning, a laboratory manual. 3 vol,
1989.
288. Sanger, F., S. Nicklen, and A R. Coulson. DNA sequencing with chain-terminating inhibitors.
Proc. Nat!. Acad. Sci., USA 74: 5463-5467, 1977.
289. Sano, H., Y. Kawahito, R. Wilder, A Hashiramoto, S. Mukai, K. Asai, S. Kimura, H. Kato, and
T. Hia. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res 55: 3785­
3789, 1995.
290. Sarraf, P., E. Mueller, D. Jones, F. J. King, D. J. DeAngelo, J. B. Partridge, S. A Holden, L. B.
Chen, S. Singer, C. Fletcher, B.M., and Spiegelman. Differentiation and reversai of malignant changes
in colon cancer through PPARgamma. Nat Med 4: 1046-1052, 1998.
291. Sarraf, P., E. Mueller, W. M. Smith, H. M. Wright, J. B. Kum, L. A. Aaltonen, A delaChapelle,
B. M. Spiegelman, and C. Eng. Loss-o-function mutations in PPAR gamma associated with human
colon cancer. Mol Ce1/3: 799-804, 1999.
292. Sasaki, H., M. Tanahashi, H. Yukiue, S. Moiriyama, Y. Kobayashi, Y. Nakashima, M. Kaji, M.
Kiriyama, 1. Fukai, Y. Yamakawa, and Y. Fujii. Decreased peroxisome proliferator-activated receptor
gamma gene expression was correlated with poor prognosis in patients with lung cancer. Lung Cancer
36: 71-76, 2002.
293. Sasaki, M., K. Sugio, and T. Sasazuzki. K-ras activation in colorectal tumors from patients with
familial polyposis coli. Cancer 65: 2576-, 1990.
294. Sato, H., S. Ishihara, K. Kawashima, N. Moriyama, H. Suetsugu, H. Kazumori, T. Okuyama, M.
Rumi, R. Fukuda, N. Nagasue, and Y. Kinoshita. Expression of peroxisome proliferator-activated
receptor (PPAR)y in gastric cancer and inhibitory effects of PPARy agonists. Br J Cancer 83: 1394­
1400,2000.
295. Satoh, S., Y. Daigo, Y. Furukawa, T. Kato, N. Miwa, T. Nishiwaki, T. Kawasoe, H. Ishiguro, M.
Fujita, T. Tokino, and e. al. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in
cancer cells by virus-mediated transfer ofAXIN1. Nat Genet 24: 245-250, 2000.
296. Schaiff, W. T., M. G. Carlson, S. D. Smith, R. Levy, D. M. Nelson, and Y. Sadovsky.
Peroxisome proliferator-activated receptor-y modulates differentiation of human trophoblast in a ligandspecific
manner. J. Clin. Endocrinol Metab 85,2000.
297. Schmidt, A, N. Endo, S. J. Rutledge, R. Vogel, D. Shinar, and G. A Rodan. Identification of a
new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator
and fatty acid. Mol. Endo. 6: 1634-1641, 1992.
298. Schoonjans, K., G. Martin, B. Staels, and J. Auwerx. Peroxisome proliferator-activated
receptors, orphans with ligands and functions. Curr Opin Lipidol8: 159-166, 1997.
299. Schoonjans, K., B. Staels, and J. Auwerx. The peroxisome proliferator activated receptors
(PPARs) and their effects on Iipid metabolism and adipocyte differentiation. Bba-Lipid Lipid Metab
1302: 93-109,1996.
300. Schoonjans, K., M. Watanabe, H. Susuki, A Mahfoudi, G. Krey, W. Wahli, P. Grimaldi, B.
Staels, T. Yamamoto, and J. Auwerx. Induction of the acyl-coenzyme A synthetase gene by fibrates
and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J. Biol.
Chem. 270: 19269-19276, 1995.
301. Schultz, R., W. Yan, J. Toppari, A Volkl, J. A Gustafsson, and M. Pelto-Huikko. Expression of
peroxisome proliferator-activated receptor alpha messenger ribonucleic acid and protein in human and
rat testis. Endocrinology 140: 2968-2975, 1999.
302. Shalev, A, C. A. Siegristkaiser, P. M. Yen, W. Wahli, A G. Burger, W. W. Chin, and C. A.
Meier. The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin.
Endocrinology 137: 4499-4502, 1996.
303. Sher, T., H. F. Yi, O. W. McBride, and F. J. Gonzalez. cDNA cloning, chromosomal mapping,
and functionnal characterization of the human peroxisome proliferator-activated receptor. Biochemistry
32: 5598-5604, 1993.
304. Shibata, D., J. Schaeffer, Z. Li, and e. al. Genetic heterogeneity of the c-K-ras locus in
colorectal adenomas but not in adenocarcinomas. J Natl Cancer Inst 85: 1058-, 1993.
305. Shoonjans, K., M. Watanabe, H. Susuki, A Mahfoudi, G. Krey, W. Wahli, P. Grimaldi, B.
Staels, T. Yamamoto, and J. Auwerx. Induction of the acyl-coenzyme A synthetase gene by fibrates
and fatty acids is mediated by a peroxisome proliferato response element in the C promoter. J. Biol.
Chem. 270: 19269-19276, 1995.
124