Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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Chemical Agents of Opportunity for Terrorism Training Support Package Participant Guide 6. Anticholinergics also cause severe constipation and an inability to urinate. Hence these patients may appear very “full” and have a large distended bladder and their colon may be full of stool. December 2008 Version 2.0 Page 110
Chemical Agents of Opportunity for Terrorism Training Support Package Participant Guide Slide 40 Chemical Agents of Opportunity for Terrorism: TICs & TIMs Modern History • 1676: a group of men led by Captain John Smith were sent to Jamestown, Virginia to quell the Bacon rebellion. • Gathered the plant now known as “Jamestown weed” (or Jimsonweed), Datura stramonium , for a salad. Module Two - The Clinical Neurotoxicology of Chemical Terrorism 40 An example of a mass poisoning with an anticholinergic compound occurred in Jamestown Virginia in 1676 during a colonial uprising known as Bacon’s rebellion. Of great toxicological interest, the British soldiers who were sent by the Colonial government to put down the rebellion ate a salad which mistakenly included Jimsonweed as one of its ingredients. The jimsonweed plant’s leaves (depicted an this slide) look like a more typical salad leaf (arugula), with scalloped edges and dark green color, and this is probably how the error occurred. Jimson weed contains the anticholinergic chemicals atropine and scopolamine. The picture on the slide also displays the characteristic tubular flower (not present in arugula). December 2008 Version 2.0 Page 111
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Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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