Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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Chemical Agents of Opportunity for Terrorism Training Support Package Participant Guide Slide 6 Chemical Agents of Opportunity for Terrorism: TICs & TIMs Thallium-Tainted Marzipan • Four young adults in NYC share premium marzipan candies recieved by mail from an “unknown admirer ” • The next day they developed diarrhea, vomiting, abdominal cramps and constipation J Toxicol Clin Toxicol. 1994;32:723 -30. Module One - Terrorism by Fear and Uncertainty: Delayed Toxic Syndromes 6 This is one example of the thallium poisoning. Four young adults received a box of candy from an unidentified “admirer”. They shared 3 candies (as can be seen in the photo of the uneaten portion above). The following day, they developed significant gastrointestinal distress, although somewhat varied in nature and severity. They came to an Emergency Department for evaluation. December 2008 Version 2.0 Page 314
Chemical Agents of Opportunity for Terrorism Training Support Package Participant Guide Slide 7 Chemical Agents of Opportunity for Terrorism: TICs & TIMs Thallium-Tainted Marzipan (cont.) • After 2 days the two who ate most (a whole candy each) developed pain in the palms and soles worse with touch – Hypertension in and EKG changes in two – Three of 4 developed alopecia (hair loss) Module One - Terrorism by Fear and Uncertainty: Delayed Toxic Syndromes 7 Gastrointestinal symptoms resolved, but a very painful paresthesia (abnormal sensation) developed – so intense as to be painful with any pressure (even bed linen) against the distal extremity skin. After about one week, symptoms progressed to involve diffuse hair loss, with additional cardiovascular signs in the two who had consumed the most. December 2008 Version 2.0 Page 315
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Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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