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Chemical Agents of Opportunity for Terrorism: TICs & TIMs

Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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<strong>Chemical</strong> <strong>Agents</strong> <strong>of</strong> <strong>Opportunity</strong> <strong>for</strong> <strong>Terrorism</strong><br />

Training Support Package<br />

Participant Guide<br />

Slide 55<br />

<strong>Chemical</strong> <strong>Agents</strong> <strong>of</strong> <strong>Opportunity</strong> <strong>for</strong> <strong>Terrorism</strong>:<br />

<strong>TICs</strong> & <strong>TIMs</strong><br />

Special Considerations<br />

• Consider adding sodium bicarbonate to nebulizer in<br />

chlorine gas exposures<br />

• Intravenous and inhaled calcium gluconate, and<br />

continuous cardiac monitoring are important <strong>for</strong><br />

hydrogen fluoride exposure<br />

• Observe patients <strong>for</strong> late pulmonary effects,<br />

particularly in those with severe early symptoms<br />

Module One – Toxic Industrial Gases as Terrorist Threats<br />

55<br />

There are some situations where specialized treatment may provide some incremental<br />

benefit. As an example, the use <strong>of</strong> sodium bicarbonate in nebulizer treatments may<br />

provide some treatment <strong>for</strong> the acid generation following chlorine inhalation.<br />

In other situations, specific treatment is definitely indicated. As examples, multiple<br />

administrations <strong>of</strong> calcium gluconate may be necessary depending on the dose and<br />

delivery route <strong>of</strong> a hydrogen fluoride exposure; and continued observation <strong>of</strong> relatively<br />

asymptomatic patients <strong>for</strong> delayed-onset pulmonary symptoms is indicated following<br />

phosgene exposure.<br />

The importance <strong>of</strong> accurate identification <strong>of</strong> the <strong>of</strong>fending agent and<br />

monitoring/treatment <strong>of</strong> “special agents” should be emphasized (and pointed out on the<br />

following summary slide). This would also be an opportunity to remind the participants <strong>of</strong><br />

the importance <strong>of</strong> correlating or comparing identification in<strong>for</strong>mation provided, with the<br />

clinical toxidromes observed. As an example, hydr<strong>of</strong>luoric acid exposure is <strong>of</strong>ten initially<br />

misidentified as hydrochloric acid exposure, but the relative predominance <strong>of</strong> systemic<br />

effects with the <strong>for</strong>mer vs. dermal effects should point out the error.<br />

December 2008 Version 2.0 Page 179

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