Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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Chemical Agents of Opportunity for Terrorism Training Support Package Participant Guide Slide 2 Chemical Agents of Opportunity for Terrorism: TICs & TIMs Learning Objectives • Review history of industrial gas exposures and regulatory response • Identify major compounds of interest • Understand the varying clinical picture created by the gases, based on their physical properties and toxicity • Address methods to decrease likelihood of exposure and illness Module One – Toxic Industrial Gases as Terrorist Threats 2 Beyond just identification of some of the major compounds in this group, this presentation will provide the participant with an understanding of the characteristic toxidromes associated with these gases, and familiarity with the national legislative and regulatory framework and local implementation that encourages threat reduction. The learning objectives for this module are as follows: Review history of industrial gas exposures and regulatory response Identify major compounds of interest Understand the varying clinical picture created by the gases, based on their physical properties and toxicity. We will discuss the physical properties in detail with each gas. Of note, the type of clinical injury seen is dependant not only on dose and inherent toxicity, but also water solubility. Address methods to decrease likelihood of exposure and illness December 2008 Version 2.0 Page 126
Chemical Agents of Opportunity for Terrorism Training Support Package Participant Guide Slide 3 Chemical Agents of Opportunity for Terrorism: TICs & TIMs Key Learning Points • Legislation to regulate TICs/TIMs was generated by concerns regarding toxic gases • Releases of large volumes of compressed gas is the most likely TIC/TIM scenario • Toxicity of a gas is determined by – Dose – Inherent toxicity – Volatility – Water solubility – Warning properties – pH Module One – Toxic Industrial Gases as Terrorist Threats 3 Recognize that much of the chemical legislation in this country and elsewhere grew out of concern following large-scale exposures. We will present several major chemical releases in this module. By far, releases of these agents form the most likely TIC/TIM scenario. These are the physical characteristics of an irritant gas that predict its specific toxicity – in particular, water solubility. Toxicity of a gas is determined: Dose Inherent toxicity Volatility Water solubility Warning properties pH December 2008 Version 2.0 Page 127
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Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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