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Chemical Agents of Opportunity for Terrorism: TICs & TIMs

Chemical Agents of Opportunity for Terrorism: TICs & TIMs

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<strong>Chemical</strong> <strong>Agents</strong> <strong>of</strong> <strong>Opportunity</strong> <strong>for</strong> <strong>Terrorism</strong><br />

Training Support Package<br />

Participant Guide<br />

Slide 31<br />

There are several algorithms that can be used to guide management and treatment<br />

decisions based on likely radiation dose received. One example is shown here where<br />

time to onset <strong>of</strong> vomiting is correlated with radiation dose. However, note that not all<br />

people will vomit, particularly at lower doses. In these situations it is helpful to have<br />

additional measurements, such as the lymphocyte depletion rate shown on the next<br />

slide.<br />

The need <strong>for</strong> early specialized care is to optimize chances <strong>for</strong> survival, which will entail<br />

strict attention to fluid and electrolyte balance, early operative care if indicated,<br />

preparation <strong>for</strong> neutropenia and use <strong>of</strong> reverse isolation procedures and specialized<br />

medications to increase bone marrow response (cytokines). The National Library <strong>of</strong><br />

Medicine site has an interactive algorithm that is very useful.<br />

December 2008 Version 2.0 Page 394

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