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Antibiotikaprofylax vid kirurgiska ingrepp - SBU

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Table 4.11.1 continued<br />

Author<br />

Year<br />

Reference<br />

Country<br />

Study<br />

design<br />

Population<br />

characteristics<br />

Intervention<br />

Method<br />

Number indi<strong>vid</strong>uals<br />

Control<br />

Number<br />

indi<strong>vid</strong>uals<br />

Results<br />

Withdrawal<br />

Drop outs<br />

Study quality<br />

and relevance<br />

Comments<br />

Nichols<br />

1994<br />

[4]<br />

USA<br />

RCT<br />

Pts with isolated blunt<br />

or traumatic thoracic<br />

trauma requiring closed<br />

tube thoracostomy.<br />

Female/male: 13/106<br />

Mean age<br />

I: 29.1 years<br />

C: 29.6 years<br />

Follow-up during hospital<br />

stay, up to 30 days<br />

I: Cefonicid 1 g iv once<br />

every 24 h until the<br />

tube was removed<br />

(n=84)<br />

C: Placebo 5%<br />

dextrose in water<br />

iv once every 24 h<br />

until the tube was<br />

removed (n=75)<br />

Total infections<br />

I: 1 pt<br />

C: 6 pts<br />

p

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