3 - Anadolu Üniversitesi

iv‹çindekiler3. ÜN‹TELaboratuvar Eti¤i .................................................................... 46G‹R‹fi .............................................................................................................. 47LABORATUVAR NED‹R? .............................................................................. 47LABORATUVAR B‹NA VE DONANIMI ....................................................... 48LABORATUVAR TÜRLER‹, ‹fiLEV VE DONANIMLARI ............................... 48Araflt›rma Laboratuvarlar› ............................................................................. 48Ölçüm Laboratuvarlar› .................................................................................. 48Ölçüm Laboratuvarlar›n›n Çal›flmas› ..................................................... 49Üniversite Araflt›rma Laboratuvarlar› ............................................................ 49‹Y‹ LABORATUVAR UYGULAMALARI ....................................................... 49Laboratuvar Kadrosu .................................................................................... 49Bafluzman›n Görev ve Sorumluluklar› ........................................................ 50Çal›flma Elemanlar›n›n Görev ve Sorumluluklar› ....................................... 50LABORATUVARLARIN KAL‹TE GÜVENCE UYGULAMASI ....................... 51LABORATUVARLARIN AKRED‹TASYONU ................................................. 51YÖNTEMLER‹N GEÇERL‹L‹⁄‹N‹N (VALIDATION) ‹NCELENMES‹ ........... 52Kesinlik (Precision) ...................................................................................... 52Do¤ruluk (Accuracy) ................................................................................... 53Seçicilik (Selectivity, Specificity) ................................................................. 53Tayin Alt S›n›r› (Limit Of Detection, LOD) ................................................ 54Saptama S›n›r› (Limit Of Quantitation, LOQ) ............................................. 54Do¤rusall›k (Linearity) ................................................................................. 54Do¤rusal Aral›k (Range) .............................................................................. 54Sa¤laml›k (Robustness) ................................................................................ 55Tutarl›l›k (Ruggedness) ................................................................................ 55Kararl›l›k (Stability) ...................................................................................... 55TEST B‹R‹MLER‹N‹N DÜZENLENMES‹ ....................................................... 55LABORATUVARLARDA ÇALIfiANLARIN SA⁄LI⁄I ..................................... 56LABORATUVAR ET‹⁄‹ ................................................................................. 56SONUÇ........................................................................................................... 57Özet ............................................................................................................... 58Kendimizi S›nayal›m ..................................................................................... 59Kendimizi S›nayal›m Yan›t Anahtar› ............................................................ 60S›ra Sizde Yan›t Anahtar› .............................................................................. 61Yararlan›lan ve Baflvurulabilecek Kaynaklar ............................................... 624. ÜN‹TEHayvan Deneyleri Eti¤i ........................................................... 64DENEY HAYVANI KAVRAMI VE DENEYLERDE KULLANILANHAYVANLAR ................................................................................................. 65DENEY HAYVANLARININ SA⁄LIK B‹L‹MLER‹NDE KULLANILMAALANLARI ...................................................................................................... 65HAYVAN DENEYLER‹ ET‹⁄‹N‹N TAR‹HSEL GEL‹fi‹M‹ ............................. 66GÜNÜMÜZDE DENEY HAYVANLARI HAKLARI: 3R KURALI ................... 67Reduction....................................................................................................... 67Refinement..................................................................................................... 68Replacement ................................................................................................. 73Doku ve Organ Kültürleri ...................................................................... 73