QF0159 Marketing Release Record

Primary Antibodies
Human seminoma: immunohistochemical staining for proliferating cell nuclear antigen using
NCL-PCNA. Note nuclear staining of proliferating tumor cells. Paraffin section.
Novocastra Prostate Specific Antigen
Clone 35H9 Reference Range
1 mL, 0.1 mL lyophilized NCL-PSA-431 P
7 mL BOND ready-to-use PA0431 P (HIER)
Clone PSA 28/A4
1 mL liquid NCL-L-PSA-28A4 ASR
Analyte Specific Reagent. Analytical and performance characteristics are
not established.
Novocastra Prostate Specific
Membrane Antigen
Clone 1D6
1 mL liquid NCL-L-PSMA ASR
Analyte Specific Reagent. Analytical and performance characteristics are
not established.
Novocastra Prostatic Acid Phosphatase
Clone PASE/4LJ
7 mL BOND ready-to-use PA0006 P (HIER)
Prostatic acid phosphatase (PAP) is an isoenzyme of acid phosphatase
found in large amounts in the prostate and seminal fluid. The precise
function of PAP is unknown, but it may act as a hydrolase to split phosphoryl
choline in semen and also function as a transferase. Elevated serum levels
of the enzyme are reported in metastatic prostatic carcinoma.
Prostate adenocarcinoma: immunohistochemical staining with Prostatic Acid Phosphatase
(PASE/4LJ) using BOND Polymer Refine Detection.
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Novocastra Prostatic Inhibin Peptide
Clone 4A6A6
1 mL lyophilized NCL-PIP P
Prostatic inhibin peptide (PIP), a 10.7 kD follicle stimulating hormone
suppressing molecule, is synthesized and secreted by the prostate gland.
PIP has been reported to be expressed in primary prostatic tumors and their
metastases. PIP has also been reported to be expressed in the serum and
urine of patients with prostatic cancer. PIP expression is unaffected by
reduced or absent androgens unlike both PSA and PAP whose expression is
dependent on androgens.
Human prostate gland: immunohistochemical staining for prostatic inhibin peptide using
NCL-PIP. Note cytoplasmic staining of glandular epithelium. Paraffin section.
Novocastra Protein Gene Product 9.5
Clone 10A1
1 mL, 0.1 mL lyophilized NCL-PGP9.5 F P (HIER) W
1 mL liquid NCL-L-PGP9.5 F P (HIER) W IVD
7 mL ready-to-use RTU-PGP9.5 F P (HIER) IVD
7 mL BOND ready-to-use PA0286 P (HIER) IVD
Antigen Background
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Protein gene product (PGP) 9.5 is a neuron specific protein, structurally and
immunologically distinct from neuron specific enolase. The protein which has
a molecular weight of 27 kD was first identified by high resolution two
dimensional PAGE. PGP9.5 expression has been reported in neurons and
nerve fibers at all levels of the central and peripheral nervous system, in many
neuroendocrine cells, in segments of the renal tubules, in spermatogonia and
Leydig cells of the testis, in ova and in some cells of both the pregnant and
non-pregnant corpus luteum. PGP9.5 is known to be a member of the ubiquitin
C-terminal hydroxylase family and is also concentrated within inclusion
bodies suggesting that such structures may be metabolically active regions
of the cells.
Novocastra pS2 Protein
Polyclonal
0.5 mL lyophilized NCL-pS2 ASR
Analyte Specific Reagent. Analytical and performance characteristics are
not established.
Products in this catalog are subject to regulatory approval.
Please consult your Leica Microsystems representative for availability in your region.
* For Research Use Only. Not for use in diagnostic procedures.
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