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QF0159 Marketing Release Record

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Primary Antibodies<br />

Novocastra Helicobacter pylori<br />

Clone ULC3R<br />

1 mL, 0.1 mL liquid NCL-L-Hpylori ASR<br />

Polyclonal<br />

1 mL lyophilized NCL-HPp ASR<br />

Analyte Specific Reagent. Analytical and performance characteristics are<br />

not established<br />

Novocastra Hepatitis C virus (NS3)<br />

Clone MMM33<br />

1 mL, 0.1 mL lyophilized NCL-HCV-NS3 F P (HIER)<br />

Antigen Background<br />

Hepatitis C virus (HCV) is the leading cause of blood-borne and community<br />

acquired non-A, non-B hepatitis. HCV infection has been estimated to affect<br />

about 3 percent of the population worldwide. Higher prevalence occurs in<br />

high-risk groups, which include individuals with a history of intravenous drug<br />

abuse and those multiply transfused before the introduction of mass<br />

screening of donated blood for viral antibodies. The virus persists in<br />

approximately 80 percent of those infected. Twenty percent of individuals<br />

with chronic infection progress to cirrhosis after an average of 20 years.<br />

Hepatocellular carcinoma is a significant risk in these, occurring in around 3<br />

percent annually. Virus antigen has been reported in the cytoplasm of<br />

hepatocytes of infected individuals by immunohistochemistry although the<br />

sensitivity of detection of antigen has varied from study to study.<br />

Product Specific Information<br />

NCL-HCV-NS3 is a monoclonal antibody raised against a recombinant NS3<br />

protein.<br />

Acutely infected human liver: immunohistochemical staining for Hepatitis C virus (HCV) nonstructural<br />

protein 3 using NCL-HCV-NS3. Note cytoplasmic staining of HCV-infected<br />

hepatocytes. Paraffin section.<br />

Novocastra Hepatocyte Growth Factor<br />

Receptor (c-MET)<br />

Clone 8F11<br />

1 mL lyophilized NCL-cMET F P (HIER)<br />

See also c-MET (Hepatocyte Growth Factor Receptor) on page 49.<br />

/70<br />

For detailed information on all products please visit our website:<br />

www.leica-microsystems.com<br />

IVD<br />

RUO*<br />

Novocastra Hepatocyte Specific<br />

Antigen<br />

Clone OCH1E5<br />

1 mL lyophilized NCL-HSA ASR<br />

Analyte Specific Reagent. Analytical and performance characteristics are<br />

not established.<br />

Novocastra Herpes simplex virus<br />

Antibodies<br />

Clone 20.7.1<br />

1 mL lyophilized Herpes simplex virus (type 1)<br />

NCL-HSV-1 ASR<br />

12.3.4, Clone 1.1.1<br />

1 mL lyophilized Herpes simplex virus (type 2)<br />

NCL-HSV-2 ASR<br />

Analyte Specific Reagent. Analytical and performance characteristics are<br />

not established.<br />

Novocastra HFSH (Beta2) (Human<br />

Follicle Stimulating Hormone)<br />

Clone INN-HFSH-60<br />

1 mL lyophilized NCL-HFSH F P (Enzyme)<br />

7 mL BOND ready-to-use PA0693 P IVD<br />

Novocastra HGH (Human Growth<br />

Hormone)<br />

Polyclonal<br />

0.25 mL lyophilized NCL-HGH FP<br />

7 mL BOND ready-to-use PA0704 P<br />

See also Human Growth Hormone (HGH) on page 72.<br />

Novocastra HGM-45M1 (Human Gastric<br />

Mucin)<br />

Clone 45M1<br />

1 mL lyophilized NCL-HGM-45M1 F P (HIER)<br />

See also Human Gastric Mucin (HGM-45M1) on page 72.<br />

IVD<br />

IVD<br />

Products in this catalog are subject to regulatory approval.<br />

Please consult your Leica Microsystems representative for availability in your region.<br />

* For Research Use Only. Not for use in diagnostic procedures.<br />

RUO*<br />

RUO*

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