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QF0159 Marketing Release Record

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Terminal Deoxynucleotidyl Transferase<br />

Clone SEN28<br />

50 Tests ORG-8865<br />

Antigen Background<br />

IVD<br />

Human TdT, a nuclear DNA polymerase with a molecular weight of 58 kD, is<br />

reported to be expressed in primitive B and T cells of the normal thymus and<br />

bone marrow, acute lymphoblastic lymphomas and leukemias.<br />

Product Specific Information<br />

The determination of TdT expression is reported to be most valuable when it<br />

is difficult to differentiate histologically between lymphoblastic lymphoma<br />

and Burkitts’ lymphoma, as such, Origin TdT (Clone SEN28) is recommended<br />

for use in the diagnosis and differentiation of acute lymphoblastic leukemia/<br />

lymphoma from other lymphomas.<br />

Refer to page 104 for further information about Clone SEN28.<br />

Origin TdT (Clone SEN28) on lymphoid leukemia. Paraffin section.<br />

F Frozen I Immunofluorescence E Electron microscopy<br />

P Paraffin C Flow cytometry O Other applications<br />

W Western blotting<br />

/ 141<br />

Origin

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