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Epidemiology of Inhalant Abuse - Archives - National Institute on ...

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Therefore, to prevent misuse, a small modificati<strong>on</strong> to the valve could<br />

limit access to the propellant (D. Roberts, British Aerosol Manufacturers’<br />

Associati<strong>on</strong>, pers<strong>on</strong>al communicati<strong>on</strong>, 1990). Gas canisters that have a<br />

screw-<strong>on</strong> valve require the possessi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> an appliance to gain access to<br />

the c<strong>on</strong>tents.<br />

Disposable cigarette lighter refills are attractive to misusers because the<br />

butane gas is accessible without use <str<strong>on</strong>g>of</str<strong>on</strong>g> an appliance. Anecdotal reports<br />

suggest that cigarette lighter refills most <str<strong>on</strong>g>of</str<strong>on</strong>g>ten are used by clenching the<br />

plastic nozzle between the teeth and pressing to release the gas. If the<br />

cylinder inadvertently is tipped up, very cold fluid (below -40°C) rather<br />

than gas is expelled. This can cause pulm<strong>on</strong>ary edema or even death<br />

from vagal inhibiti<strong>on</strong> (Shepherd 1989). Modificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the valve <strong>on</strong><br />

cigarette lighter refills should be c<strong>on</strong>sidered to reduce this practice.<br />

<str<strong>on</strong>g>Abuse</str<strong>on</strong>g> <str<strong>on</strong>g>of</str<strong>on</strong>g> disposable cigarette lighters themselves, although <str<strong>on</strong>g>of</str<strong>on</strong>g>ten referred<br />

to, is unlikely because they c<strong>on</strong>tain very little gas (typically 4 ml <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

liquid) and the flow rate is restricted. The flammability <str<strong>on</strong>g>of</str<strong>on</strong>g> butane gives<br />

rise to the risk <str<strong>on</strong>g>of</str<strong>on</strong>g> bums resulting from misuse, usually when an<br />

intoxicated youngster decides to smoke and sniff butane at the same time<br />

(Scerri et al. 1992). Elliott (1991) reports cold bums (i.e., frostbite) <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

the mouth <str<strong>on</strong>g>of</str<strong>on</strong>g> a soldier who had inhaled a propellant c<strong>on</strong>taining propane<br />

and dichlorodifluoromethane (FC 12).<br />

The internati<strong>on</strong>al c<strong>on</strong>trol <str<strong>on</strong>g>of</str<strong>on</strong>g> the manufacture <str<strong>on</strong>g>of</str<strong>on</strong>g> halogenated compounds<br />

suspected <str<strong>on</strong>g>of</str<strong>on</strong>g> depleting stratospheric oz<strong>on</strong>e (table 1) will necessitate<br />

changes in the formulati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> some products abused by inhalati<strong>on</strong>.<br />

Typewriter correcti<strong>on</strong> fluids, as well as cleaning and degreasing agents,<br />

will no l<strong>on</strong>ger c<strong>on</strong>tain 1, 1, 1-trichloroethane, which is relatively safe<br />

during chr<strong>on</strong>ic occupati<strong>on</strong>al exposure. It can be expected that the more<br />

toxic trichloroethylene and, perhaps, dichloromethane will be substituted<br />

in some applicati<strong>on</strong>s. On the positive side, bromochlorodifluoromethane<br />

(BCF, FC 12B1) probably will be replaced by carb<strong>on</strong> dioxide in fire<br />

extinguishers.<br />

Based <strong>on</strong> mortality data and anecdotal reports, gasoline is not comm<strong>on</strong>ly<br />

misused in the United Kingdom, in c<strong>on</strong>trast to the United States, where<br />

gasoline vied with glue as the top “ever used” product in the 1991<br />

<str<strong>on</strong>g>Nati<strong>on</strong>al</str<strong>on</strong>g> Household Survey <strong>on</strong> Drug <str<strong>on</strong>g>Abuse</str<strong>on</strong>g> (Sharp 1992). It perhaps is<br />

more understandable that populati<strong>on</strong>s such as native Australians (Brady<br />

1991) and the aboriginal populati<strong>on</strong>s <str<strong>on</strong>g>of</str<strong>on</strong>g> some other countries (Smart<br />

1988), who do not have access to c<strong>on</strong>sumer products, should use this, the<br />

<strong>on</strong>ly readily available volatile compound. The hazard from lead additives<br />

207

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