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Chapter – 2 Microwave assisted simple and fast…..
6. After C3-N4 and N4-C5 bond cleavages, C7-N4 bond cleavage gave
characteristic peak at 189 m/e. [6]
7. After C7-N4 bond cleavage, C7-C8 bond cleavage gave characteristic
peak at 176 m/e. [7]
8. After C7-C8 bond cleavage, C9-N10 and subsequently C11-C19 and C12-
C20 bond cleavages gave characteristic peak at 121 m/e. [8]
9. N4-C7 bond cleavage in the title compound gave characteristic peak at
189 m/e, which could be the alternative possibility for this fragment. [9]
10. C7-C8 bond cleavage in the title compound gave two characteristic
peaks at 176 m/e and 101 m/e, which could be the alternative
possibility. [10]
2.6.1.3 FRAGMENTATION PATTERN FOR DNJ-502
O
20
O
20
O
20
O
20
17
18
13
12
17
18
13
12
17
18
13
12
17
18
13
12
16
15
14
11
N
10
O
19 [1] 16
15
14
11
N
10
O
19 [2] 16
15
14
11
N
10
O
19
[3] 16
15
14
11
N
10
274 m/e
9
262 m/e
9
246 m/e 9
234 m/e 9
8
8
8
8
6
O 1
[9]
5
2
189 m/e
O
92 m/e
N
4
3
NH
7
N
CH 3
+.
O
O
[10]
H3C 6
+. +.
176 m/e
O
C
H 3
N
101 m/e
N
O
CH 3
+.
5
H3C 2
O
N
4
3
7
17
16
189 m/e
17
16
18
15
+.
[7]
18
15
176 m/e
13
14
13
14
8
H3C 8
O 20
12
11
N
10
9
CH 3
7
O 20
12
11
N
10
9
+.
205 m/e
121 m/e
Department of Chemistry, Saurashtra University, Rajkot – 360 005 92
O 19
O 19
H3C 6
[6]
[8]
5
N 4
7
CH 3
3
17
16
18
15
+.
13
14
H2N 4
8
12
11
N
10
7
N
H
O 20
9
O 19
[5]
H3C 5
17
16
N 4
[4]
7
CH 3
3
+. +. +.
+.
18
15
13
14
218 m/e
H3C 5
+.
8
NH
4
O 19
12
11
N
10
7
O 20
9
O 19